Screening of the venoms of two Parabuthus scorpion species on isolated cardiomyocytes

Van Aarde, M.N.; Van Rooyen, J.M.; Van Aswegen, G.

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1996 Onderstepoort Journal of Veterinary Research, Volume 63, 1996
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dc.contributor.author	Van Aarde, M.N.
dc.contributor.author	Van Rooyen, J.M.
dc.contributor.author	Van Aswegen, G.
dc.contributor.editor	Verwoerd, Daniel Wynand
dc.date.accessioned	2013-08-27T07:25:32Z
dc.date.available	2013-08-27T07:25:32Z
dc.date.created	2013
dc.date.issued	1996
dc.description	The articles have been scanned in colour with a HP Scanjet 5590; 600dpi. Adobe Acrobat X Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format.	en
dc.description.abstract	Crude, diluted venoms of Parabuthus transvaalicus and P. granulatus were tested on isolated cardiomyocytes. Ventricular myocytes were subjected to hypercontractility tests and whole-cell voltage clamp. Both venoms had a profound influence on the hypercontractility of cardiomyocytes, which was markedly decreased when they were pre-absorbed with commercial antiserum. Whole-cell clamp results showed an increase in the sodium current, and a retardation of the time course of inactivation, implicating the presence of an a toxin in both venoms.	en
dc.description.librarian	mn2013
dc.identifier.citation	Van Aarde, MN, Van Rooyen, JM & Van Aswegen, G 1996, 'Screening of the venoms of two Parabuthus scorpion species on isolated cardiomyocytes’. Onderstepoort Journal of Veterinary Research, vol. 63, no. 2, pp. 127-130.	en
dc.identifier.issn	0330-2465
dc.identifier.uri	http://hdl.handle.net/2263/22070
dc.language.iso	en	en
dc.publisher	Published by the Agricultural Research Council, Onderstepoort Veterinary Institute	en
dc.rights	© ARC-Onderstepoort (original). © University of Pretoria. Dept of Library Services (digital).	en
dc.subject	Veterinary medicine	en
dc.subject	Cardiomyocytes	en
dc.subject	Parabuthus granulatus	en
dc.subject	Parabuthus transvaalicus	en
dc.subject	Scorpions	en
dc.subject	Venom	en
dc.subject.lcsh	Veterinary medicine -- South Africa
dc.title	Screening of the venoms of two Parabuthus scorpion species on isolated cardiomyocytes	en
dc.type	Article	en