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dc.contributor.author | Knobel, Darryn Leslie![]() |
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dc.contributor.author | Maina, Alice N.![]() |
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dc.contributor.author | Cutler, Sally J.![]() |
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dc.contributor.author | Ogola, Eric![]() |
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dc.contributor.author | Feikin, Daniel R.![]() |
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dc.contributor.author | Junghae, Muthoni![]() |
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dc.contributor.author | Halliday, Jo E.B.![]() |
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dc.contributor.author | Richards, Allen L.![]() |
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dc.contributor.author | Breiman, Robert F.![]() |
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dc.contributor.author | Cleaveland, Sarah![]() |
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dc.contributor.author | Njenga, M. Kariuki![]() |
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dc.date.accessioned | 2013-04-17T07:03:40Z | |
dc.date.available | 2014-02-04T00:20:04Z | |
dc.date.issued | 2013-02-04 | |
dc.description.abstract | We conducted serological surveys for Coxiella burnetii in archived sera from patients that visited a rural clinic in western Kenya from 2007 to 2008 and in cattle, sheep, and goats from the same area in 2009. We also conducted serological and polymerase chain reaction-based surveillance for the pathogen in 2009–2010, in human patients with acute lower respiratory illness, in ruminants following parturition, and in ticks collected from ruminants and domestic dogs. Antibodies against C. burnetii were detected in 30.9% (N = 246) of archived patient sera and in 28.3% (N = 463) of cattle, 32.0% (N = 378) of goats, and 18.2% (N = 159) of sheep surveyed. Four of 135 (3%) patients with acute lower respiratory illness showed seroconversion to C. burnetii. The pathogen was detected by polymerase chain reaction in specimens collected from three of six small ruminants that gave birth within the preceding 24 hours, and in five of 10 pools (50%) of Haemaphysalis leachi ticks collected from domestic dogs. | en |
dc.description.librarian | am2013 | en |
dc.description.librarian | ab2013 | |
dc.description.sponsorship | This research was supported by the Wellcome Trust, UK (grant no. 081828/B/06/Z) and U.S. Centers of Disease Control and Prevention and Global Emerging Infections Surveillance and Response System Program (work unit no. 188M.0931.001.A0074). | en |
dc.description.uri | http://www.ajtmh.org/ | en |
dc.identifier.citation | Knobel, DL, Maina, AN, Cutler, SJ, Ogola, E, Feikin, DR, Junghae, M, Halliday, JoEB, Richards, AL, Breiman, RF, Cleaveland, S & Njenga, MK 2013, 'Coxiella burnetii in humans, domestic ruminants, and ticks in rural Western Kenya', American Journal of Tropical Medicine and Hygiene, vol. 88, no. 3, pp. 513-518. | en |
dc.identifier.issn | 0002-9637 (print) | |
dc.identifier.issn | 1476-1645 (online) | |
dc.identifier.other | 10.4269/ajtmh.12-0169 | |
dc.identifier.other | 6602518021 | |
dc.identifier.other | 0000-0002-0425-3799 | |
dc.identifier.other | O-7057-2014 | |
dc.identifier.uri | http://hdl.handle.net/2263/21293 | |
dc.language.iso | en | en |
dc.publisher | American Society of Tropical Medicine and Hygiene | en |
dc.relation.requires | Adobe Acrobat Reader | en |
dc.rights | © The American Society of Tropical Medicine and Hygiene. | en |
dc.subject | Domestic ruminants | en |
dc.subject | Rural Western Kenya | en |
dc.subject.lcsh | Coxiella burnetii | en |
dc.subject.lcsh | Ruminants | en |
dc.subject.lcsh | Ticks | en |
dc.subject.lcsh | Human beings | en |
dc.title | Coxiella burnetii in humans, domestic ruminants, and ticks in rural Western Kenya | en |
dc.type | Article | en |