• Molecular detection of Rickettsia africae in Amblyomma ticks collected in cattle from Southern and Central Mozambique 

  Magaia, Vlademiro; Taviani, Elisa; Cangi, Nidia; Neves, L.C.B.G.D. (Luís) (Open Learning on Enteric Pathogens, 2020-06)

  INTRODUCTION : Rickettsia are Gram-negative and obligate intracellular bacteria, which cause typhus and spotted fever-like diseases in humans. In Africa, Rickettsia africae of the Spotted Fever Group Rickettsia (SFGR) is ...
• Co-infection best predicts respiratory viral infection in a wild host 

  Glidden, Caroline K.; Coon, C.A.C. (Courtney); Beechler, Brianna R.; McNulty, Chase; Ezenwa, Vanessa O.; Jolles, Anna E. (Wiley, 2021-03)

  1. The dynamics of directly transmitted pathogens in natural populations are likely to result from the combined effects of host traits, pathogen biology, and interactions among pathogens within a host. Discovering how ...
• A unique isolation of a lytic bacteriophage infected Bacillus anthracis isolate from Pafuri, South Africa 

  Hassim, Ayesha; Lekota, Kgaugelo Edward; Van Dyk, David Schalk; Dekker, Edgar Henry; Van Heerden, Henriette (MDPI, 2020-06-20)

  Bacillus anthracis is a soil-borne, Gram-positive endospore-forming bacterium and the causative agent of anthrax. It is enzootic in Pafuri, Kruger National Park in South Africa. The bacterium is amplified in a wild ...
• Investigating selective media for optimal isolation of Brucella spp. in South Africa 

  Ledwaba, Maphuti Betty; Ndumnego, Okechukwu C.; Matle, Itumeleng; Gelaw, Awoke K.; Van Heerden, Henriette (AOSIS OpenJournals, 2020-03-04)

  Bovine brucellosis in South Africa is caused mainly by Brucella abortus biovar (bv.) 1 and less frequently by B. abortus bv. 2. Bacterial isolation is regarded as the gold standard for diagnosis of Brucella species; ...
• In vitro propagation and genome sequencing of three ‘atypical’ Ehrlichia ruminantium isolates 

  Liebenberg, Junita; Steyn, Helena C.; Josemans, Antoinette I.; Faber, Erika; Zweygarth, Erich (AOSIS OpenJournals, 2020-06-24)

  Three isolates of Ehrlichia ruminantium (Kümm 2, Omatjenne and Riverside), the causative agent of heartwater in domestic ruminants, were isolated in Ixodes scapularis (IDE8) tick cell cultures using the leukocyte fraction ...
• Survey of the knowledge, attitude and perceptions on bovine tuberculosis in Mnisi community, Mpumalanga, South Africa 

  Marange, Rudo; Morar-Leather, Darshana; Fasina, Folorunso Oludayo (AOSIS OpenJournals, 2020-07-30)

  Tuberculosis (TB) is a global health concern of zoonotic importance, and Mycobacterium bovis and Mycobacterium tuberculosis are the most common causes of TB in animals and humans, respectively. Integral to TB control ...
• Hsp70 and nf-kb mediated control of innate inflammatory responses in a canine macrophage cell line 

  Lyu, Qingkang; Wawrzyniuk, Magdalena; Rutten, Victor P.M.G.; Sijts, Alice J.A.M.; Broere, Femke (MDPI, 2020-09)

  The pathogenesis of many inflammatory diseases is associated with the uncontrolled activation of nuclear factor kappa B (NF-κB) in macrophages. Previous studies have shown that in various cell types, heat shock protein ...
• Immunogenicity of non-living anthrax vaccine candidates in cattle and protective efficacy of immune sera in A/J mouse model compared to the sterne live spore vaccine 

  Jauro, Solomon; Ndumnego, Okechukwu C.; Ellis, Charlotte; Buys, Angela; Beyer, Wolfgang (MDPI, 2020-07-10)

  The Sterne live spore vaccine (SLSV, Bacillus anthracis strain 34F2) is the veterinary vaccine of choice against anthrax though contra-indicated for use with antimicrobials. However, the use of non-living anthrax vaccine ...
• Molecular detection of tick‑borne pathogens in caracals (Caracal caracal) living in human‑modified landscapes of South Africa 

  Viljoen, Storme; O’Riain, M. Justin; Penzhorn, Barend Louis; Drouilly, Marine; Serieys, Laurel E.K.; Cristescu, Bogdan; Teichman, Kristine J.; Bishop, Jacqueline M. (BioMed Central, 2020-04-30)

  BACKGROUND : Wild carnivores living alongside humans and domestic animals are vulnerable to changes in the infectious disease dynamics in their populations. The aims of this study were to determine the prevalence and ...
• Evaluation of the relative roles of the Tabanidae and Glossinidae in the transmission of trypanosomosis in drug resistance hotspots in Mozambique 

  Mulandane, Fernando C.; Snyman, Louwtjie P.; Brito, Denise R.A.; Bouyer, Jeremy; Fafetine, Jose; Van Den Abbeele, Jan; Oosthuizen, Marinda C.; Delespaux, Vincent; Neves, L.C.B.G.D. (Luís) (BioMed Central, 2020-04-29)

  BACKGROUND : Tsetse flies (Diptera: Glossinidae) and tabanids (Diptera: Tabanidae) are haematophagous insects of medical and veterinary importance due to their respective role in the biological and mechanical transmission ...
• Invasive cattle ticks in East Africa : morphological and molecular confirmation of the presence of Rhipicephalus microplus in south‑eastern Uganda 

  Muhanguzi, Dennis; Byaruhanga, Joseph; Amanyire, Wilson; Ndekezi, Christian; Ochwo, Sylvester; Nkamwesiga, Joseph; Mwiine, Frank Norbert; Tweyongyere, Robert; Josephus Fourie; Madder, Maxime; Schetters, Theo; Horak, Ivan Gerard; Juleff, Nick; Jongejan, Frans (BioMed Central, 2020-04-03)

  BACKGROUND : Rhipicephalus microplus, an invasive tick species of Asian origin and the main vector of Babesia species, is considered one of the most widespread ectoparasites of livestock. The tick has spread from its ...
• Analysis of p67 allelic sequences reveals a subtype of allele type 1 unique to buffalo-derived Theileria parva parasites from southern Africa 

  Mukolwe, Lubembe D.; Odongo, David O.; Byaruhanga, Charles; Snyman, Louwtjie P.; Sibeko-Matjila, K.P. (Kgomotso Penelope) (Public Library of Science, 2020-06-29)

  East Coast fever (ECF) and Corridor disease (CD) caused by cattle- and buffalo-derived T. parva respectively are the most economically important tick-borne diseases of cattle in the affected African countries. The p67 ...
• Economic and feasibility comparison of the dRIT and DFA for decentralized rabies diagnosis in resource-limited settings : the use of Nigerian dog meat markets as a case study 

  Ukamaka, Eze U.; Coetzer, Andre; Scott, Terence Peter; Anene, Boniface M.; Ezeokonkwo, Romanus C.; Nwosuh, Chika I.; Nel, Louis Hendrik; Sabeta, Claude Taurai (Public Library of Science, 2020-02-28)

  BACKGROUND : Rabies lyssavirus (RABV) is the aetiologic agent of rabies, a disease that is severely underreported in Nigeria as well as elsewhere in Africa and Asia. Despite the role that rabies diagnosis plays towards ...
• Reservoirs and transmission routes of leprosy : a systematic review 

  Ploemacher, Thomas; Faber, William R.; Menke, Henk; Rutten, Victor P.M.G.; Pieters, Toine (Public Library of Science, 2020-04-27)

  Leprosy is a chronic infectious disease caused by Mycobacterium leprae (M. leprae) and the more recently discovered Mycobacterium lepromatosis (M. lepromatosis). The two leprosy bacilli cause similar pathologic conditions. ...
• Risk practices for bovine tuberculosis transmission to cattle and livestock farming communities living at wildlife-livestock-human interface in northern KwaZulu Natal, South Africa 

  Sichewo, Petronillah Rudo; Vander Kelen, Catiane; Thys, Severine; Michel, Anita Luise (Public Library of Science, 2020-03-30)

  Bovine tuberculosis (bTB) is a disease of cattle that is transmitted through direct contact with an infected animal or ingestion of contaminated food or water. This study seeks to explore the local knowledge on bTB, ...
• Differential immunomodulation of porcine bone marrow derived dendritic cells by E. coli Nissle 1917 and β-glucans 

  Geervliet, Mirelle; Lute, Laura C.P.; Jansen, Christine A.; Rutten, Victor P.M.G.; Savelkoul, Huub F.J.; Tijhaar, Edwin (Public Library of Science, 2020-06-19)

  In early life and around weaning, pigs are at risk of developing infectious diseases which compromise animal welfare and have major economic consequences for the pig industry. A promising strategy to enhance resistance ...
• Reflections on IDEAL : what we have learnt from a unique calf cohort study 

  Callaby, R.; Jennings, A.; Mwangi, S.T.; Mbole-Kariuki, M.; Van Wyk, Ilana; Kiara, H.; Coetzer, Jacobus A.W.; Woolhouse, M.E.J.; Hanotte, O.; Toye, P.G.; DeC. Bronsvoort, B.M. (Elsevier, 2020-08)

  The year 2020 marks a decade since the final visit was made in the ‘Infectious Diseases of East African Livestock’ (IDEAL) project. However, data generation from samples obtained during this ambitious longitudinal study ...
• Early life inoculation with adult-derived microbiot maturation of intestinal microbiota and enhances NK cell activation in broiler chickens 

  Meijerink, Nathalie; Kers, Jannigje G.; Velker, Francisca C.; Velker, Francisca C.; Lamot, David M.; De Oliveira, Jean E.; Smidt, Hauke; Stegeman, J. Arjan; Rutten, Victor P.M.G.; Jansen, Christine A. (Frontiers Media, 2020-11)

  Studies in mammals, including chickens, have shown that the development of the immune system is affected by interactions with intestinal microbiota. Early life microbial colonization may affect the development of innate ...
• Knowledge, attitudes, and perceptions associated with antimicrobial stewardship among veterinary students : a multi-country survey from Nigeria, South Africa, and Sudan 

  Fasina, Folorunso Oludayo; LeRoux-Pullen, Lerica; Smith, Peter.; Debusho, Legesse K.; Shittu, Aminu; Jajere, Saleh M.; Adebowale, Oluwawemimo Oluseun; Odetokun, Ismail; Agbaje, Michael; Fasina, Modupe M.; Fasanmi, Olubunmi G.; Van Dyk, Deborah; Abubakar, Mohammed S.; Onakpa, Monday M.; Ali, Masaad G.; Yousuf, Hozaifa S.; Elmgboul, Waliedin E.; Sirdar, Mohamed Mahmoud (Frontiers Media, 2020-10)

  In African countries, antimicrobial resistance (AMR) issue remains pertinent. Despite this, little efforts have been made to assess the future veterinary prescribers on their knowledge, attitudes and practices (KAP) ...
• IDEAL, the Infectious Diseases of East African Livestock project open access database and biobank 

  Callaby, Rebecca; Pendarovski, Cezar; Jennings, Amy; Mwangi, Samuel Thumbi; Van Wyk, Ilana; Mbole-Kariuki, Mary; Kiara, Henry; Toye, Philip G.; Kemp, Steve; Hanotte, Olivier; Coetzer, Jacobus A.W.; Handel, Ian G.; Woolhouse, Mark E.J.; De Clare Bronsvoort, Barend Mark (Nature Publishing Group, 2020-07-09)

  The Infectious Diseases of East African Livestock (IDEAL) project was a longitudinal cohort study of calf health which was conducted in Western Kenya between 2007–2010. A total of 548 East African shorthorn zebu calves ...

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