• Spatiotemporal epidemiology of rabies at an interface between domestic dogs and wildlife in South Africa 

  Grover, Michael; Bessell, Paul R.; Conan, Anne; Polak, Pim; Sabeta, Claude Taurai; Reininghaus, Bjorn; Knobel, Darryn Leslie (Nature Publishing Group, 2018-07-18)

  We characterized the spatiotemporal epidemiology of rabies from January 2009 through March 2014 across the interface between a wildlife reserve and communal livestock farming area in South Africa. Brain tissue from 344 ...
• Phylogenetic analysis of canine distemper virus in South African wildlife 

  Loots, Angelina K.; Mokgokong, Prudent S.; Mitchell, Emily; Venter, Estelle Hildegard; Kotze, Antoinette; Dalton, Desire Lee (Public Library of Science, 2018-07-18)

  Canine distemper virus (CDV) causes a severe contagious disease in a broad range of hosts. This is the first study to genetically characterise CDV strains from four different wildlife species in South Africa. The ...
• Large outbreaks of fungal and bacterial bloodstream infections in a neonatal unit, South Africa, 2012–2016 

  Van Schalkwyk, Erika; Iyaloo, Samantha; Naicker, Serisha D.; Maphanga, Tsidiso G.; Mpembe, Ruth S.; Zulu, Thokozile G.; Mhlanga, Mabatho; Mahlangu, Sibongile; Maloba, Motlatji B.; Ntlemo, Grace; Sanyane, Kgomotso; Mawela, Dini; Govender, Nelesh P. (Centers for Disease Control and Prevention, 2018-07)

  Candidemia is a major cause of healthcare-associated infections. We describe a large outbreak of Candida krusei bloodstream infections among infants in Gauteng Province, South Africa, during a 4-month period; a series of ...
• Identification and characterisation of conserved epitopes of E. ruminantium that activate Th1 CD4+ T cells : towards the development of a multi-epitope vaccine 

  Thema, Nontobeko; Tshilwane, Selaelo I.; Pretorius, Alri; Son, L.; Smith, R.M.; Steyn, Helena C.; Liebenberg, Junita; Van Kleef, Mirinda (Elsevier, 2019-03)

  Several studies have shown that cytotoxic T lymphocytes (CTL) require CD4 + Th1 epitopes to generate strong immune responses to intracellular pathogens. However, not much is known about Ehrlichia ruminantium epitopes, ...
• Integrative taxonomy of Afrotropical Ornithodoros (Ornithodoros) (Acari: Ixodida: Argasidae) 

  Bakkes, Deon K.; De Klerk, Daniel; Latif, Abdalla A.; Mans, Ben J. (Barend Johannes) (Elsevier, 2018-05)

  Afrotropical Ornithodoros (Ornithodoros) ticks are revised based on qualitative morphology of females and nymphs, as well as tarsus I shape outlines of females measured in a geometric morphometric framework. These lines ...
• Longitudinal monitoring of Culicoides in Belgium between 2007 and 2011 : local variation in population dynamics parameters warrant cautious use of monitoring data 

  Sohier, Charlotte; Deblauwe, Isra; De Deken, Reginald; Madder, Maxime; Fassotte, Christiane; Losson, Bertrand; De Regge, Nick (BioMed Central, 2018-09-17)

  BACKGROUND : Several European countries suffered important economic losses during the past decade due to the emergence of bluetongue and Schmallenberg viruses. Both are viruses of veterinary importance and are spread by ...
• Helminth composition and prevalence of indigenous and invasive synanthropic murid rodents in urban areas of Gauteng Province, South Africa 

  Julius, R.S. (Rolanda); Schwan, E.V. (Volker); Chimimba, Christian Timothy (Cambridge University Press, 2018-07)

  Although synanthropic rodents such as the indigenous species, Mastomys coucha, and the invasive species, Rattus norvegicus, R. rattus and R. tanezumi, are well-known to be hosts to various micro- and macroparasites, their ...
• Safety and immunogenicity of plant‑produced African horse sickness virus‑like particles in horses 

  Dennis, Susan J.; O’Kennedy, Martha M.; Rutkowska, Daria; Tsekoa, Tsepo; Lourens, Carina W.; Hitzeroth, Inga I.; Meyers, Ann E.; Rybicki, Edward P. (BioMed Central, 2018-10-11)

  African horse sickness (AHS) is caused by multiple serotypes of the dsRNA AHSV and is a major scourge of domestic equids in Africa. While there are well established commercial live attenuated vaccines produced in South ...
• Development and validation of a multiplex, real-time PCR assay for Babesia rossi and Babesia vogeli 

  Troskie, Milana; De Villiers, Lourens; Leisewitz, Andrew L.; Oosthuizen, Marinda C.; Quan, Melvyn (Elsevier, 2019-02)

  Canine babesiosis is caused by tick-transmitted intraerythrocytic protozoan parasites occurring worldwide. In southern Africa, babesiosis is caused by Babesia rossi and B. vogeli and is one of the most common and important ...
• Cross reactive immune responses in cattle arising from exposure to Mycobacterium bovis and non-tuberculous mycobacteria 

  Jenkins, Akinbowale Olajide; Gormley, Eamonn; Gcebe, Nomakorinte; Fosgate, Geoffrey T.; Conan, Anne; Aagaard, Claus Sindbjerg; Michel, Anita Luise; Rutten, Victor P.M.G. (Elsevier, 2018-04)

  Accurate diagnosis of tuberculosis in cattle may be compromised in areas where there are high rates of exposure to environmental/non-tuberculous mycobacteria (NTM). This cross reaction of immune responses to Mycobacterium ...
• Antigen-specific CD4+ and CD8+ T-cell responses in PBMC from pony mares immunized with either native or recombinant zona pellucida vaccines 

  Joone, C.J. (Carolynne); Schulman, M.L. (Martin); Fosgate, Geoffrey T.; Plagis, T.A.; Crafford, Jan Ernst; Gupta, Satish K.; Bertschinger, H.J. (Hendrik Jan) (Elsevier, 2019-03)

  Few studies have investigated the cell mediated immune response during zona pellucida-based immunocontraception, despite hypothesized cytotoxic T-cell involvement in ovarian dysfunction associated with these vaccines. This ...
• Ehrlichia ruminantium antigens and peptides induce cytotoxic T cell responses in vitro 

  Thema, Nontobeko; Tshilwane, Selaelo I.; Son, L.; Smith, R.M.; Faber, Frederika E.; Steyn, Helena C.; Van Kleef, Mirinda; Liebenberg, Junita; Pretorius, Alri (Elsevier, 2019-01)

  Since CD8+ T cells play an important role in resistance to infection with heartwater, effective vaccines against this disease will likely require identification of antigens that contain CD8+ T cell epitopes responsible for ...
• Development of a real-time RT-PCR assay specific for the Winterfield 2512 strain of infectious bursal disease virus 

  Kabajani, Juliet Ndubu (University of Pretoria, 2018)

  Cevac® Transmune® IBD was developed by CEVA Santé Animale for vaccination of poultry against infectious bursal disease (IBD, or Gumboro). The vaccine contains the Winterfield 2512 (W2512) strain of infectious bursal disease ...
• Molecular characterisation of potential vaccine candidates from Anaplasma marginale strains in South Africa 

  Hove, Paidashe (University of Pretoria, 2018)

  Bovine anaplasmosis, a tick-borne disease caused by the rickettsia Anaplasma marginale, has a significant economic impact for cattle farmers in South Africa. We have estimated the economic cost due to mortality arising ...
• Attitudes of veterinarians to the changes in provision of bovine tuberculosis testing in England 

  Gerber, Karen (University of Pretoria, 2018)

  The number of cattle herds in the UK newly infected with bovine tuberculosis (Mycobacterium bovis) has doubled every nine years since 1979. Controlling bovine tuberculosis (bTB) currently costs the British taxpayer an ...
• Occurrence of tick-borne haemoparasites in selected South African wild rodent species in the Mnisi Communal area 

  de Boni, Liesl (University of Pretoria, 2018)

  In 2013, a disease survey of people in the Mnisi community, Bushbuckridge, Mpumalanga, South Africa revealed a surprisingly high level of exposure to tick bite fever, Bartonella, Q fever and leptospirosis. This indicated ...
• Screening of captive lions (Panthera leo) for selected infectious diseases of significance in Zimbabwe 

  Vhoko, Kudzaishe (University of Pretoria, 2018)

  Fifteen lions from three captive/semi-captive establishments around Harare were captured for blood sampling. Routine health checks for viral diseases and other diseases of economic, public health or biodiversity conservation ...
• Species composition of ticks and tick-borne pathogens in domestic ruminants and dogs in Tchicala-Tcholoanga Huambo Province Angola 

  Sili, Gourgélia Do Nascimento Fortuna (University of Pretoria, 2018)

  This study was conducted to determine the composition of ticks and tick-borne pathogens, circulating in livestock in Tchicala-Tcholoanga Municipality, Huambo Province, Angola. Samples were collected from cattle, goats, ...
• Modelling the transmission dynamics and the effect of different control strategies for African swine fever virus in East Africa 

  Bitamale, Mike Barongo (University of Pretoria, 2018)

  African swine fever (ASF) is a highly contagious, lethal and economically devastating haemorrhagic disease of domestic pigs. Knowledge of the epidemiology of the disease is important for the design of improved control ...
• Spatio-temporal variation in the dipping frequency of communal cattle at the wildlife-livestock interface in the Mnisi study area Mpumalanga South Africa 

  Murapa, Rumbidzai Emily (University of Pretoria, 2018)

  Tick burden and tick-borne diseases (TBDs) in cattle have for centuries plagued most parts of southern Africa, hence the adoption of various tick control strategies. The most commonly used method of tick control has been ...

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