• Locally-curved geometry generates bending cracks in the African elephant skin 

  Martins, Antonio F.; Bennett, Nigel C., 1961-; Clavel, Sylvie; Groenewald, Hermanus B.; Hensman, Sean; Hoby, Stefan; Joris, Antoine; Manger, Paul R.; Milinkovitch, Michel C. (Nature Publising Group, 2018-10-02)

  An intricate network of crevices adorns the skin surface of the African bush elephant, Loxodonta africana. These micrometre-wide channels enhance the effectiveness of thermal regulation (by water retention) as well as ...
• Benzofuran–appended 4-aminoquinazoline hybrids as epidermal growth factor receptor tyrosine kinase inhibitors: synthesis, biological evaluation and molecular docking studies 

  Mphahlele, Malose J.; Maluleka, Marole M.; Aro, A.O. (Abimbola); McGaw, Lyndy Joy; Choong, Yee Siew (Informa Healthcare, 2018)

  A series of 2-arylbenzo[b]furan–appended 4-aminoquinazoline hybrids were prepared and evaluated for cytotoxicity in vitro against the human lung cancer (A549), colorectal adenocarcinoma (Caco-2), hepatocellular carcinoma ...
• Safety and immunogenicity of plant‑produced African horse sickness virus‑like particles in horses 

  Dennis, Susan J.; O’Kennedy, Martha M.; Rutkowska, Daria; Tsekoa, Tsepo; Lourens, Carina W.; Hitzeroth, Inga I.; Meyers, Ann E.; Rybicki, Edward P. (BioMed Central, 2018-10-11)

  African horse sickness (AHS) is caused by multiple serotypes of the dsRNA AHSV and is a major scourge of domestic equids in Africa. While there are well established commercial live attenuated vaccines produced in South ...
• Development and validation of a multiplex, real-time PCR assay for Babesia rossi and Babesia vogeli 

  Troskie, Milana; De Villiers, Lourens; Leisewitz, Andrew L.; Oosthuizen, Marinda C.; Quan, Melvyn (Elsevier, 2019-02)

  Canine babesiosis is caused by tick-transmitted intraerythrocytic protozoan parasites occurring worldwide. In southern Africa, babesiosis is caused by Babesia rossi and B. vogeli and is one of the most common and important ...
• Anti-inflammatory and antioxidant properties of leaf extracts of eleven South African medicinal plants used traditionally to treat inflammation 

  Ondua, Moise; Njoya, Emmanuel Mfotie; Abdalla, Muna Ali; McGaw, Lyndy Joy (Elsevier, 2019-04)

  ETHNOPHARMACOLOGICAL RELEVANCE : Inflammation is a complex mechanism employed by the body to promote healing and restoration to normal function in the event of injury. Eleven plant species were selected in this study based ...
• Tropical summer induces DNA fragmentation in boar spermatozoa : implications for evaluating seasonal infertility 

  Peña, Santiago T.; Stone, Felicity; Gummow, Bruce; Parker, Anthony J.; Paris, Damien B.B.P. (CSIRO Publishing, 2019)

  Summer infertility continues to undermine pig productivity, costing the pig industry millions in annual losses. The boar's inefficient capacity to sweat, non-pendulous scrotum and the extensive use of European breeds in ...
• Lesions and cellular tropism of natural Rift Valley fever virus infection in adult sheep 

  Odendaal, Lieza; Clift, Sarah J.; Fosgate, Geoffrey T.; Davis, A.S. (Sally) (Sage, 2019-10)

  Rift Valley fever (RVF) is a mosquito-borne disease that affects both ruminants and humans, with epidemics occurring more frequently in recent years in Africa and the Middle East, probably as a result of climate change and ...
• Cross reactive immune responses in cattle arising from exposure to Mycobacterium bovis and non-tuberculous mycobacteria 

  Jenkins, Akinbowale Olajide; Gormley, Eamonn; Gcebe, Nomakorinte; Fosgate, Geoffrey T.; Conan, Anne; Aagaard, Claus Sindbjerg; Michel, Anita Luise; Rutten, Victor P.M.G. (Elsevier, 2018-04)

  Accurate diagnosis of tuberculosis in cattle may be compromised in areas where there are high rates of exposure to environmental/non-tuberculous mycobacteria (NTM). This cross reaction of immune responses to Mycobacterium ...
• Short communication : Characterization of enterotoxin producing Staphylococcus aureus isolated from mastitic cows 

  Grispoldi, Luca; Massetti, Luca; Sechi, Paola; Iulietto, Maria F.; Ceccarelli, Margherita; Karama, Musafiri; Popescu, Paul A.; Pandolfi, Francesco; Cenci-Goga, Beniamino T. (American Dairy Science Association, 2019-02)

  Staphylococcus aureus is not only a common cause of bovine mastitis, but also an agent of food poisoning in humans. In an attempt to determine whether staphylococci causing bovine mastitis could also cause food poisoning, ...
• Temporal patterns of anthrax outbreaks among livestock in Lesotho, 2005-2016 

  Lepheana, Relebohile Juliet; Oguttu, James Wabwire; Qekwana, Daniel Nenene (Public Library of Science, 2018-10-24)

  BACKGROUND : Although anthrax is endemic in Lesotho, limited information is available on the patterns of the disease among livestock animals. This study investigated temporal patterns of anthrax outbreaks and cases ...
• Antigen-specific CD4+ and CD8+ T-cell responses in PBMC from pony mares immunized with either native or recombinant zona pellucida vaccines 

  Joone, C.J. (Carolynne); Schulman, M.L. (Martin); Fosgate, Geoffrey T.; Plagis, T.A.; Crafford, Jan Ernst; Gupta, Satish K.; Bertschinger, H.J. (Hendrik Jan) (Elsevier, 2019-03)

  Few studies have investigated the cell mediated immune response during zona pellucida-based immunocontraception, despite hypothesized cytotoxic T-cell involvement in ovarian dysfunction associated with these vaccines. This ...
• Chemotherapeutic efficacy of implantable antineoplastic-treatment protocols in an optimal mouse model for human ovarian carcinoma cell targeting 

  Pantshwa, Jonathan M.; Rhoda, Khadija; Clift, Sarah J.; Pradeep, Priyamvada; Choonara, Yahya E.; Kumar, Pradeep; Du Toit, Lisa C.; Penny, Clement; Pillay, Viness; Pillay, Viness (MDPI Publishing, 2018-10-04)

  The present study aimed to design and develop a nanocomposite drug delivery system employing an antineoplastic-loaded antibody functionalized nanomicelle encapsulated within a Chitosan–Poly(vinylpyrrolidone)–Poly(N-iso ...
• Skeletal muscle fibrosis : an overview 

  Mahdy, M.A.A. (Mohamed) (Springer, 2019-11)

  Extracellular matrix (ECM) is an essential component of skeletal muscle. It provides a framework structure that holds myofibers and blood capillaries and nerves supplying the muscle. In addition, it has a principal role ...
• Ehrlichia ruminantium antigens and peptides induce cytotoxic T cell responses in vitro 

  Thema, Nontobeko; Tshilwane, Selaelo I.; Son, L.; Smith, R.M.; Faber, Frederika E.; Steyn, Helena C.; Van Kleef, Mirinda; Liebenberg, Junita; Pretorius, Alri (Elsevier, 2019-01)

  Since CD8+ T cells play an important role in resistance to infection with heartwater, effective vaccines against this disease will likely require identification of antigens that contain CD8+ T cell epitopes responsible for ...
• Experimental infection of racing pigeons (Columba livia domestica) with highly pathogenic Clade 2.3.4.4 sub-group B H5N8 avian influenza virus 

  Abolnik, Celia; Stutchbury, Savannah; Hartman, Marthinus Jacobus (Elsevier, 2018-12)

  Please read abstract in the article.
• Could the environmental toxicity of diclofenac in vultures been predictable if preclinical testing methodology were applied? 

  Hassan, Ibrahim Zubairu; Duncan, N.M. (Neil); Adawaren, Emmanuel Oluwasegun; Naidoo, Vinny (Elsevier, 2018-12)

  Diclofenac, a non-steroidal anti-inflammatory pharmaceutical agent was responsible for the death of millions of Gyps vulture’s in the Indian sub-region with the safety of the other non-steroidal anti-inflammatory drugs ...
• Serum albumin concentration of donor cows as an indicator of developmental competence of oocytes 

  Smuts, M.P. (Mario); De Bruyn, Sonya; Thompson, P.N. (Peter N.); Holm, D.E. (Dietmar Erik) (Elsevier, 2019-02)

  Adequate nutrition is required for maintenance of normal reproduction in cattle. Albumin, the best marker and fundamental part of nutrition, most abundant plasma protein and major component of fetal bovine serum, is the ...
• Food safety control of products of animal origin : bovine 

  Amar, Shira; Van der Merwe, Uldri; Kruger, Shannon; University of Pretoria. Faculty of Veterinary Science (Pretoria : University of Pretoria, Faculty of Veterinary Science, 2018)

  The EFSA Scientific Opinion on the public health hazards to be covered by inspection of meat classifies Salmonella spp. (non-typhoidal) and E.coli O157:H7 as high priority biological hazards. Listeria monocytogenes, ...
• Food safety control of products of animal origin : porcine 

  Nkomo, Louisa; Kamburona, Kavekatora; University of Pretoria. Faculty of Veterinary Science (Pretoria : University of Pretoria, Faculty of Veterinary Science, 2018)

  The poster highlights the EFSA's opinion vs South Africa on pig public health, the chemical hazards and welfare conditions in the South African pig industry and meat inspection in South Africa. In South Africa measures are ...
• Food safety control of products of animal origin : poultry 

  Mthembu, Lethiwe; Cuthill, Hayden; University of Pretoria. Faculty of Veterinary Science (Pretoria : University of Pretoria, Faculty of Veterinary Science, 2018)

  As a third world country, South Africa relies on research output from Europe. Many of South Africa's veterinary regulation attempt to follow European standards. It is not always possible due to restraints both financially ...

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