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Browsing Research Articles (Immunology) by UP Author "Dessels, Carla"
Now showing items 1-6 of 6
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Dessels, Carla; Durandt, Chrisna; Pepper, Michael Sean (Taylor and Francis, 2019)Pooled human platelet lysate (pHPL) has been used to expand adipose-derived stromal cells (ASCs) and can be formulated using fresh or expired buffy coats (BCs) which are then resuspended in either plasma or an additive ...
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Durandt, Chrisna; Dessels, Carla; Da Silva, C.; Murdoch, Candice; Pepper, Michael Sean (Nature Publishing Group, 2019-11-04)Multipotent adipose-derived stromal/stem cells (ASCs) are candidates for use in cellular therapies for the treatment of a variety of conditions/diseases. Ex vivo expansion of freshly isolated ASCs may be necessary prior ...
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Dessels, Carla; Ambele, Melvin Anyasi; Pepper, Michael Sean (BMC, 2019-08)BACKGROUND: For adipose-derived stromal cells (ASCs) to be safe for use in the clinical setting, they need to be prepared using good manufacturing practices (GMPs). Fetal bovine serum (FBS), used to expand ASCs in vitro ...
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Dessels, Carla; Alessandrini, Marco; Pepper, Michael Sean (Wiley Open Access, 2018-09)Hematopoietic stem cell transplantation (HSCT) is common practice today for life threatening malignant and non-malignant diseases of the blood and immune systems. Umbilical cord blood (UCB) is rich in hematopoietic stem ...
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Durandt, Chrisna; Van Vollenstee, Fiona A.; Dessels, Carla; Kallmeyer, Karlien; De Villiers, Danielle; Murdoch, Candice; Potgieter, Marnie; Pepper, Michael Sean (American Society for Biochemistry and Molecular Biology, 2016-04)The ability of mesenchymal stromal cells (MSCs) to differentiate into adipocytes provides a cellular model of human origin to study adipogenesis in vitro. One of the major challenges in studying adipogenesis is the lack of ...
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Dessels, Carla; Pepper, Michael Sean (Mary Ann Liebert, 2019-06)Adipose-derived stromal cells (ASCs) are becoming increasingly attractive as cellular therapy products. Their differentiation potential, the secretion of growth and differentiation factors, and the ability to cryopreserve ...
Now showing items 1-6 of 6