Browsing Research Articles (Immunology) by Author "Warnich, Louise"

Browsing Research Articles (Immunology) by Author "Warnich, Louise"

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  • Evaluation of predictive CYP2C19 genotyping assays relative to measured phenotype in a South African cohort 
    Dodgen, Tyren Mark; Drögemöller, Britt I.; Wright, Galen E.B.; Warnich, Louise; Steffens, Francois E.; Cromarty, Allan Duncan; Alessandrini, Marco; Pepper, Michael Sean (Future Medicine, 2015-08)
    AIM : To align predicted and measured CYP2C19 phenotype in a South African cohort. MATERIALS AND METHODS : Genotyping of CYP2C19*2, *3, *9, *15, *17, *27 and *28 was performed using PCR-RFLP, and an Activity Score (AS) ...
  • Introduction of the AmpliChip CYP450 test to a South African cohort : a platform comparative prospective cohort study 
    Dodgen, Tyren Mark; Hochfeld, Warren Ernst; Fickl, Heidi; Asfaha, Sahle M.; Durandt, Chrisna; Rheeder, Paul; Drögemoller, Britt I.; Wright, Galen E.B.; Warnich, Louise; Labuschagne, Christiaan D.J.; Van Schalkwyk, Antoinette; Gaedigk, Andrea; Pepper, Michael Sean (BioMed Central, 2013-01-29)
    BACKGROUND: Adverse drug reactions and lack of therapeutic efficacy associated with currently prescribed pharmacotherapeutics may be attributed, in part, to inter-individual variability in drug metabolism. Studies on ...
  • Whole-genome sequencing for an enhanced understanding of genetic variation among South Africans 
    Choudhury, Ananyo; Ramsay, Michele; Hazelhurst, Scott; Aron, Shaun; Bardien, Soraya; Botha, Gerrit; Chimusa, Emile R.; Christoffels, Alan; Gamieldien, Junaid; Sefid-Dashti, Mahjoubeh J.; Joubert, Fourie; Meintjes, Ayton; Mulder, Nicola; Ramesar, Raj; Rees, Jasper; Scholtz, Kathrine; Sengupta, Dhriti; Soodyall, Himla; Venter, Philip; Warnich, Louise; Pepper, Michael Sean (Nature Publishing Group, 2017-12-12)
    The Southern African Human Genome Programme is a national initiative that aspires to unlock the unique genetic character of southern African populations for a better understanding of human genetic diversity. In this pilot ...