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Browsing Immunology by Author "Feldman, Charles"
Now showing items 1-20 of 58
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Opolot, J.O.; Theron, Annette J.; Anderson, Ronald; Feldman, Charles (Springer, 2015-02)INTRODUCTION : Despite the high burden of disease, there have been surprisingly few studies of the acute phase and plasma catecholamine/cortisol stress hormone responses in patients with active pulmonary tuberculosis. ...
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Richards, Guy A.; Gray, Claudia L.; De Waal, Pieter; Friedman, Ray; Hockman, Maurice; Karabus, Sarah J.; Lodder, Cornelia M.; Mabelane, Tshegofatso; Mosito, Sylvia M.; Nanan, Ashen; Peter, Jonny G.; Quitter, Traugott H.C.; Van den Berg, Sylvia; Van Niekerk, Andre; Vardas, Eftyhia; Feldman, Charles (AOSIS, 2023-10-30)BACKGROUND : Allergic rhinitis (AR) has a significant impact on the community as a whole with regard to quality of life and its relationship to allergic multi-morbidities. Appropriate diagnosis, treatment and review of ...
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Feldman, Charles; Anderson, Ronald (Thieme Publishing, 2012-06)Community-acquired pneumonia remains an important cause of disease and death both in the developed and the developing worlds and therefore continues to have major medical impact. The mortality remains high despite the ...
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Feldman, Charles; Anderson, Ronald (Adis, 2011-01)Streptococcus pneumoniae is the major bacterial cause of pneumonia, meningitis and otitis media and continues to be associated with significant morbidity and mortality in individuals both in the developed and developing ...
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Feldman, Charles; Anderson, Ronald (Thieme Publishing, 2016-04)Opportunistic bacterial and fungal infections of the lower respiratory tract, most commonly those caused by Streptococcus pneumoniae (the pneumococcus), Mycobacterium tuberculosis, and Pneumocystis jirovecii, remain the ...
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Anderson, Ronald; Theron, Annette J.; Steel, Helen C.; Durandt, Chrisna; Tintinger, Gregory Ronald; Feldman, Charles (Hindawi Publishing Corporation, 2014-03)The clinical relevance of the anti-inflammatory properties of beta-2 agonists remains contentious possibly due to differences in their molecular structures and agonist activities. The current study has compared the effects ...
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Cockeran, Riana; Dix-Peek, Therese; Dickens, Caroline; Steel, Helen C.; Anderson, Ronald; Feldman, Charles (Elsevier, 2020-02)OBJECTIVES : Exposure to cigarette smoke impacts on the virulence of Streptococcus pneumoniae (pneumococcus) by mechanisms including induction of biofilm formation. Most studies, however, have focused on individual strains ...
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Feldman, Charles; Anderson, Ronald (South African Thoracic Society, 2020)COVID-19 pneumonia, much like that of bacterial and viral community-acquired pneumonia before it, is accompanied by a high rate of cardio- and cerebrovascular events that are associated with an increased risk of complications ...
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Cardiac troponin T as a predictor of short- and long-term mortality in community-acquired pneumonia Feldman, Charles; Anderson, Ronald (Wiley, 2017-07)The association between severe community-acquired pneumonia (CAP) and a significantly heightened risk for development of an acute cardiovascular event (ACE), most commonly acute myocardial infarction, new-onset arrhythmia ...
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Cockeran, Riana; Steel, Helen C.; Theron, Annette J.; Mitchell, Timothy J.; Feldman, Charles; Anderson, Ronald (Elsevier, 2011-11)The pneumolysin toxoid, Δ6 PLY, is a prototype pneumococcal protein vaccine candidate. However, its potentially detrimental residual pro-inflammatory interactions with human neutrophils are unknown. In the current study ...
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Matapa, Kgashane Given; Dix-Peek, Therese; Cockeran, Riana; Anderson, Ronald; Steel, Helen C.; Feldman, Charles (European Publishing, 2019-11)INTRODUCTION : Cigarette smoking is a well-recognized risk factor for development of severe, invasive pneumococcal disease. However, little is known about the direct effects of exposure to cigarette smoke on the virulence ...
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Anderson, Ronald; Steel, Helen C.; Cockeran, Riana; Smith, Anthony M.; Von Gottberg, Anne; De Gouveia, L.; Brink, Andries J.; Klugman, Keith P.; Mitchell, Timothy J.; Feldman, Charles (Oxford University Press, 2007-02)Please refer to abstract in article
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Anderson, Ronald; Theron, Annette J.; Nel, Jan Gert; Durandt, Chrisna; Cholo, Moloko C.; Feldman, Charles; Tintinger, Gregory Ronald (Frontiers Media, 2018-11-20)Although the inclusion of the cationic amphiphilic, anti-mycobacterial agent, clofazimine, in the chemotherapeutic regimens of patients with multidrug-resistant tuberculosis (TB) has contributed to improved outcomes, ...
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Feldman, Charles; Anderson, Ronald (Elsevier, 2015-08)Despite advances in antimicrobial chemotherapy and access to sophisticated intensive care facilities, bacterial community-acquired pneumonia (CAP) continues to carry an unacceptably high mortality rate of 10% to 15% in ...
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Feldman, Charles; Anderson, Ronald (Lippincott, Williams & Wilkins, 2016-10)PURPOSE OF REVIEW : Describe recent studies that may impact on the management of community-acquired pneumonia (CAP). RECENT FINDINGS : CAP continues to be associated with a considerable burden of disease. Diagnosis remains ...
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Richards, G.A.; Theron, Annette J.; Van den Bout, Jan Iman; Anderson, Ronald; Feldman, Charles; Van Zyl Smit, Richard; Chang, Ju-Wei; Tintinger, Gregory (European Respiratory Society, 2023-05)BACKGROUND : Electronic cigarettes (ECs) are electronic aerosol delivery systems composed of nicotine and various chemicals, which are widely used to facilitate smoking cessation. Although ECs are considered safer than ...
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Anderson, Ronald; Steel, Helen C.; Cockeran, Riana; Von Gottberg, Anne; De Gouveia, L.; Klugman, Keith P.; Mitchell, Timothy J.; Feldman, Charles (Oxford University Press, 2007-11)OBJECTIVES: To compare the effects of subinhibitory concentrations of amoxicillin, ceftriaxone, azithromycin, clarithromycin, erythromycin, telithromycin, clindamycin, ciprofloxacin, moxifloxacin, tobramycin and doxycycline ...
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Feldman, Charles; Anderson, Ronald (AME Publishing Company, 2016-03)Improving the outcome of patients with community-acquired pneumonia (CAP) is an ongoing challenge, even in the setting of significant advances in antimicrobial chemotherapy and critical care. Recognition of the underlying ...
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Theron, Annette J.; Steel, Helen C.; Tintinger, Gregory Ronald; Gravett, Cornelia M.; Anderson, Ronald; Feldman, Charles (Hindawi Publishing Corporation, 2014)Cysteinyl leukotrienes (cysLTs) are produced predominantly by cells of the innate immune system, especially basophils, eosinophils, mast cells, and monocytes/macrophages. Notwithstanding potent bronchoconstrictor activity, ...
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Steel, Helen C.; Venter, Willem Daniel Francois; Theron, Annette J.; Anderson, Ronald; Feldman, Charles; Arulappan, Natasha; Rossouw, Theresa M. (MDPI, 2021-01-29)Systemic biomarkers of inflammation, including cytokines and chemokines, are potentially useful in the management of both HIV infection and non-AIDS-defining disorders. However, relatively little is known about the utility ...
Now showing items 1-20 of 58