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Browsing Immunology by Author "Cockeran, Riana"
Now showing items 1-12 of 12
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Cockeran, Riana; Dix-Peek, Therese; Dickens, Caroline; Steel, Helen C.; Anderson, Ronald; Feldman, Charles (Elsevier, 2020-02)OBJECTIVES : Exposure to cigarette smoke impacts on the virulence of Streptococcus pneumoniae (pneumococcus) by mechanisms including induction of biofilm formation. Most studies, however, have focused on individual strains ...
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Cockeran, Riana; Steel, Helen C.; Theron, Annette J.; Mitchell, Timothy J.; Feldman, Charles; Anderson, Ronald (Elsevier, 2011-11)The pneumolysin toxoid, Δ6 PLY, is a prototype pneumococcal protein vaccine candidate. However, its potentially detrimental residual pro-inflammatory interactions with human neutrophils are unknown. In the current study ...
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Matapa, Kgashane Given; Dix-Peek, Therese; Cockeran, Riana; Anderson, Ronald; Steel, Helen C.; Feldman, Charles (European Publishing, 2019-11)INTRODUCTION : Cigarette smoking is a well-recognized risk factor for development of severe, invasive pneumococcal disease. However, little is known about the direct effects of exposure to cigarette smoke on the virulence ...
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Anderson, Ronald; Steel, Helen C.; Cockeran, Riana; Smith, Anthony M.; Von Gottberg, Anne; De Gouveia, L.; Brink, Andries J.; Klugman, Keith P.; Mitchell, Timothy J.; Feldman, Charles (Oxford University Press, 2007-02)Please refer to abstract in article
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Anderson, Ronald; Steel, Helen C.; Cockeran, Riana; Von Gottberg, Anne; De Gouveia, L.; Klugman, Keith P.; Mitchell, Timothy J.; Feldman, Charles (Oxford University Press, 2007-11)OBJECTIVES: To compare the effects of subinhibitory concentrations of amoxicillin, ceftriaxone, azithromycin, clarithromycin, erythromycin, telithromycin, clindamycin, ciprofloxacin, moxifloxacin, tobramycin and doxycycline ...
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Cockeran, Riana; Steel, Helen C.; Wolter, Nicole; De Gouveia, L.; Von Gottberg, Anne; Klugman, Keith P.; Leanord, A.T.; Inverarity, D.J.; Mitchell, Timothy J.; Feldman, Charles; Anderson, Ronald (Scientific Research Publishing Inc, 2012-02)AIM: To investigate the effects of exposure of a macrolide-resistant [erm(B)-expressing] strain of Streptococcus pneumo- niae (strain 2507) to clarithromycin (0.5 and 5 mg/L) added at the outset and 6 hours after initiation ...
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Potjo, Moliehi; Cockeran, Riana; Theron, Annette J.; Feldman, Charles; Anderson, Ronald (Molecular Diversity Preservation International, 2010)Moxifloxacin is useful in the treatment of respiratory infections, including community-acquired pneumonia, and also shows promise in the treatment of tuberculosis, a clinical setting which necessitates extended administration ...
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Cockeran, Riana (University of Pretoria, 2005-09-22)The Streptococcus pneumoniae-derived toxin, pneumolysin, has been reported to augment neutrophil-mediated inflammatory responses in murine models of experimental infection of the airways, and to favour invasive pneumococcal ...
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Cockeran, Riana; Herbert, Jenny A.; Mitchell, Timothy J.; Dix-Peek, Thérèse; Dickens, Caroline; Anderson, Ronald; Feldman, Charles (Hindawi Publishing Corporation, 2014-07)Alterations in whole genome expression profiles following exposure of the pneumococcus (strain 172, serotype 23F) to cigarette smoke condensate (160 μg/mL) for 15 and 60 min have been determined using the TIGR4 DNA microarray ...
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Richards, Guy A.; Brink, Adrian J.; McIntosh, Ross; Steel, Helen C.; Cockeran, Riana (Dove Medical Press, 2014-07)Catheter-related blood stream infections increase morbidity, mortality, and costs. This study investigated whether Certofix® protect antimicrobial catheters carry a surface charge and whether this inhibits biofilm formation. ...
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Steel, Helen C.; Cockeran, Riana; Anderson, Ronald; Feldman, Charles; Bermejo-Martin, Jesus F. (Hindawi Publishing Corporation, 2013)Community-acquired pneumonia (CAP) remains a leading cause of morbidity and mortality among the infectious diseases.Despite the implementation of national pneumococcal polyvalent vaccine-based immunisation strategies ...
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Steel, Helen C.; Theron, Annette J.; Cockeran, Riana; Anderson, Ronald; Feldman, Charles; Asano, Kazuhito (Hindawi Publishing Corporation, 2012)Macrolide antibiotics possess several, beneficial, secondary properties which complement their primary antimicrobial activity. In addition to high levels of tissue penetration, whichmay counteract seemingly macrolide-resistant ...
Now showing items 1-12 of 12