Helena, Jolene Michelle; Joubert, Anna Margaretha; Grobbelaar, Simone; Nolte, Elsie Magdalena; Nel, Marcel; Pepper, Michael Sean; Coetzee, Magdalena; Mercier, Anne Elisabeth(MDPI Publishing, 2018-04-11)
Deoxyribonucleic acid (DNA) is the self-replicating hereditary material that provides a
blueprint which, in collaboration with environmental influences, produces a structural and functional
phenotype. As DNA coordinates ...
Helena, Jolene Michelle; Joubert, Anna Margaretha; Mabeta, Peaceful Lucy; Coetzee, Magdalena; Lakier, Roy; Mercier, Anne Elisabeth(MDPI, 2021-08-17)
2-Ethyl-3-O-sulfamoyl-estra-1,3,5(10)16-tetraene (ESE-16) is an in silico-designed estradiol
analogue which has improved the parent compound’s efficacy in anti-cancer studies. In this proofof-
concept study, the potential ...
