Vitex doniana leaves are used in traditional medicine systems for the treatment of inflammatory-related disorders and breast cancer in West Africa. However, there is a dearth of scientific evidence on the effectiveness of ...
Repsold, Lisa; Pool, Roger; Karodia, Mohammed; Tintinger, Gregory Ronald; Becker, Piet J.; Joubert, Anna Margaretha(Wiley, 2021-06)
Chronic myeloid leukaemia (CML) is a malignancy of the haematopoietic stem cells. The first line of treatment for CML, especially in developing countries, remains the first-generation tyrosine kinase inhibitor, Imatinib. ...
Viljoen, Margaretha; Bipath, Priyesh; Tosh, Cheryl A.(Cambridge University Press, 2021-06)
OBJECTIVE : Pellagra is a nutritional deficiency disease associated with niacin (vitamin B3) deficiency. The history of pellagra is well documented for Europe and the USA, but less is known about the prevalence in sub-Saharan ...
Botha, Carolin-Mari; Rossouw, France; Meyer, P.W.A. (Pieter Willem Adriaan); Camacho, Tanya Chantelle de Sousa(Routledge, 2022)
Repetitive upper-quarter limb movements imposed by freestyle swimming may lead to muscle length and tension changes, predisposing adolescent swimmers to postural malalignment. The study aimed to quantify the static ...
Helena, Jolene Michelle; Joubert, Anna Margaretha; Mabeta, Peaceful Lucy; Coetzee, Magdalena; Lakier, Roy; Mercier, Anne Elisabeth(MDPI, 2021-08-17)
2-Ethyl-3-O-sulfamoyl-estra-1,3,5(10)16-tetraene (ESE-16) is an in silico-designed estradiol
analogue which has improved the parent compound’s efficacy in anti-cancer studies. In this proofof-
concept study, the potential ...
Lower resting energy expenditure (REE) may partially explain the disproportionate prevalence of overweight/obesity among black African women. As no previous studies have investigated
the REE of Southern African (South. ...
De Beer, Rene; Outhoff, Kim; Phulukdaree, Alisa; Soma, Prashilla(Taylor and Francis, 2021)
Statins, the standard treatment for hypercholesterolaemia, among the most widely prescribed, have been associated with side effects, including statin intolerance. The aim of this study was to determine the background ...
Hene, Nceba; Wood, Paola Silvia; Schwellnus, Martin Peter; Jordaan, Esme; Laubscher, Ria(Lippincott Williams and Wilkins, 2021-10)
OBJECTIVE : To determine if repeat annual health risk assessments (RAHRAs) with intervention reduce 10-year cardiovascular disease (CVD) risk in financial sector employees.
METHODS : Retrospective analysis from RAHRAs in ...
Hene, Nceba; Wood, Paola Silvia; Schwellnus, Martin Peter; Jordaan, Esme; Laubscher, Ria(Lippincott, Williams & Wilkins, 2021-02)
OBJECTIVE : To determine the prevalence of non-communicable disease (NCD) risk factors, total NCD risk category and 10-year risk for cardiovascular diseases (CVD) in financial sector employees.
METHODS : This descriptive ...
Van der Bijl, Ivo; Nawaz, Kalim; Kazlauskaite, Ugne; Van Stalborch, Anne-Marieke; Tol, Simon; Jimenez Orgaz, Ana; Van den Bout, Jan Iman; Reinhard, Nathalie R.; Sonnenberg, Arnoud; Margadant, Coert(Elsevier, 2020-11)
Collective cell behaviour during embryogenesis and tissue repair requires the coordination of intercellular junctions, cytoskeleton-dependent shape changes controlled by Rho GTPases, and integrin-dependent cell-matrix ...
Van der Westhuizen, Danielle; Slabber, Cathryn A.; Fernandes, Manuel A.; Joubert, Daniel Francois; Kleinhans, George; Van der Westhuizen, Carl Johan; Stander, Andre; Munro, Orde; Bezuidenhout, Daniela Ina(Wiley, 2021-06)
The syntheses of bis(triazolium)carbazole precursors
and their corresponding coinage metal (Au, Ag) complexes
are reported. For alkylated triazolium salts, di- or tetranuclear
complexes with bridging ligands were isolated, ...
Bayne, Helen; Albertus, Yumna; Breen, Sarah; Green, Andrew; De Andrade, Andre Gustavo; Kramer, Mark; Carpes, Felipe P.(American Physiological Society, 2021-03)
The “Biomechanics without Borders: Teaching Biomechanics in Brazil and South Africa” involved academics from different countries combining efforts to improve remote education. In addition to the live discussions, the event ...
Bayne, Helen; Albertus, Yumna; Breen, Sarah; Green, Andrew; De Andrade, Andre Gustavo; Kramer, Mark; Carpes, Felipe P.(American Physiological Society, 2021)
The “Biomechanics without Borders: Teaching Biomechanics in Brazil and South Africa” involved academics from different countries combining efforts to improve remote education. In addition to the live discussions, the event ...
Vitamin D has displayed anti-cancer actions in numerous in vitro studies. Here,
we investigated the anti-cancer actions of cholecalciferol, a vitamin D precursor, on a metastatic
cervical cancer cell line, namely, CaSki. ...
Patulin (PAT) is a common mycotoxin contaminant of apple products linked to impaired metabolic and
kidney function. Adenosine monophosphate activated protein kinase (AMPK), abundantly expressed
in the kidney, intercedes ...
Nolte, Kim; Janse van Rensburg, Dina Christina; Fletcher, Lizelle(OASIS, 2021-06)
BACKGROUND : Respiratory morbidity is common in children with neuromuscular diseases (NMD) owing to chronic hypoventilation and impaired cough. Optimal, cost-effective respiratory management requires implementation of ...
Balt, Karlien; Du Toit, Peet J.; Smith, Mark; Janse van Rensburg, Charl(International Society for Neurofeedback & Research, 2020-06)
Peripheral body monitoring of autonomic nervous system (ANS) response has been routinely applied during infraslow fluctuation (ISF) neurofeedback training. This study hypothesized that ISF training has a distinct physiological ...
The effect of neonatal oral supplementation of oleanolic acid (OA) on peroxisome proliferator-activated
receptor gamma
(PPARγ)-1 on glucose homeostasis in high fructose-fed
rats was investigated. Rat pups (7 days old) ...