Browsing Research Articles (Physiology) by Subject "Luteinizing hormone (LH)"

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Continuous kisspeptin restores luteinizing hormone pulsatility following cessation by a neurokinin B antagonist in female sheep

Clarke, Iain J.; Li, Qun; Henry, Belinda A.; Millar, Robert P. (Oxford University Press, 2018-02)

Pulsatile secretion of the gonadotropin-releasing hormone (GnRH) drives pulsatile secretion of the luteinizing hormone (LH), with evidence that this depends on kisspeptin (Kiss) input to GnRH neurons. Kiss administration ...
Hypothalamic-pituitary-ovarian axis reactivation by kisspeptin-10 in hyperprolactinemic women with chronic amenorrhea

Millar, Robert P.; Sonigo, Charlotte; Anderson, Richard A.; George, Jyothis; Maione, Luigi; Brailly-Tabard, Sylvie; Chanson, Philippe; Binart, Nadine; Young, Jacques (Endocrine Society, 2017-11)

CONTEXT : Hyperprolactinemia-induced hypogonadotropic amenorrhea (hPRL-HA) is a major cause of hypothalamic gonadotrophin-releasing hormone (GnRH) deficiency in women. In hyperprolactinemic mice, we previously demonstrated ...

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