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Browsing Research Articles (Medical Microbiology) by UP Author "Mbelle, Nontombi Marylucy"
Now showing items 1-20 of 32
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Said, Mohamed; Dangor, Yusuf; Mbelle, Nontombi Marylucy; Madhi, S.A.; Kwatra, G.; Ismail, F. (Health and Medical Publishing Group, 2020-09)BACKGROUND. Streptococcus agalactiae or group B streptococcus (GBS) is a significant cause of neonatal sepsis. Intrapartum antibiotic prophylaxis is recommended for pregnant women identified to be rectovaginally colonised ...
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Bamford, Colleen; Bonorchis, Kim; Ryan, Anthea; Simpson, John; Elliott, Eugenne; Hoffmann, Rena; Naicker, Preneshni; Ismail, Nazir Ahmed; Mbelle, Nontombi Marylucy; Nchabeleng, Maphoshane; Nana, Trusha; Sriruttan, Charlotte; Seetharam, Sharona; Wadula, Jeannette (Federation of Infectious Diseases Societies of South Africa, 2011)We report on antimicrobial susceptibility surveillance data for six key bloodstream pathogens (Escherichia coli, Klebsiella pneumoniae, Enterobacter spp., Pseudomonas aeruginosa, Acinetobacter baumannii and Staphylococcus ...
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Osei Sekyere, John; Sephofane, Arnold Karabo; Mbelle, Nontombi Marylucy (Nature Publishing Group, 2020-04-10)Colistin has become a critical antibiotic for fatal Gram-negative infections owing to the proliferation of multidrug-resistant carbapenemase-producing bacteria. Thus, cheaper, faster, efficient and easier-touse colistin ...
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Osei Sekyere, John; Maphalala, Nontobeko; Malinga, Lesibana Anthony; Mbelle, Nontombi Marylucy; Maningi, Nontuthuko Excellent (Nature Publising Group, 2019-11)Studies evaluating the new GeneXpert Ultra with other rapid diagnostic assays are limited, particularly in diferent geographical settings. The performance of the GeneXpert Ultra, the GeneXpert G4, the Line probe assays ...
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Maningi, Nontuthuko Excellent; Malinga, Lesibana Anthony; Antiabong, John Francis; Lekalakala, Ruth M.; Mbelle, Nontombi Marylucy (BioMed Central, 2017-12-28)BACKGROUND : The incidence of multidrug-resistant tuberculosis (MDR-TB) is increasing and the emergence of extensively drug-resistant tuberculosis (XDR-TB) is a major challenge. Controlling resistance, reducing transmission and ...
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Said, Mohamed; Dangor, Yusuf; Mbelle, Nontombi Marylucy; Sihlabela, A.; Lekalakala, M.R.; Ismail, Farzana (Health and Medical Publishing Group, 2018-12)BACKGROUND. Group B streptococcus (GBS) is a leading cause of invasive disease, particularly in newborns. Seventy-five percent of neonates will be colonised by mothers carrying the organism. Confirmation of maternal ...
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Leshaba, Tumisho Mmatumelo Seipei; Mbelle, Nontombi Marylucy; Sekyere, John Osei (Wiley, 2022-01)The emergence of polymyxin resistance, due to transferable mcr genes, threatens public and animal health as there are limited therapeutic options. As polymyxin is one of the last-line antibiotics, there is a need to ...
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Tshisevhe, V.S.; Mbelle, Nontombi Marylucy; Peters, Remco P.H. (AOSIS Open Journals, 2019-03-12)INTRODUCTION : Extrapulmonary tuberculosis (TB) causes a significant burden of disease worldwide, especially among HIV-infected individuals and those with other immunosuppressive conditions. Cutaneous TB is an important ...
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Draft genome sequence of a clinical Enterococcus faecium sequence type 18 strain from South Africa Mbelle, Nontombi Marylucy; Maningi, Nontuthuko Excellent; Tshisevhe, Vhudzani; Modipane, Lesedi; Amoako, Daniel Gyamfi; Sekyere, John Osei (American Society for Microbiology, 2017-11-30)We report the first draft genome sequence of an Enterococcus faecium sequence type 18 (ST18) strain isolated from a tuberculosis patient in Africa. The genome is comprised of 3,202,539 bp, 501 contigs, 37.70% GC content, ...
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Osei Sekyere, John; Maningi, Nontuthuko Excellent; Modipane, Lesedi; Mbelle, Nontombi Marylucy (American Society for Microbiology, 2020-05)Extended-spectrum-β-lactamase (ESBL)-producing Enterobacteriaceae are critical-priority pathogens that cause substantial fatalities. With the emergence of mobile mcr genes mediating resistance to colistin in Enterobacteriaceae, ...
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Mmatli, Masego; Mbelle, Nontombi Marylucy; Maningi, Nontuthuko Excellent; Osei Sekyere, John (American Society for Microbiology, 2020-11)The spread of carbapenem- and polymyxin-resistant Enterobacteriaceae poses a significant threat to public health, challenging clinicians worldwide with limited therapeutic options. This review describes the current coding ...
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Kopotsa, Katlego; Mbelle, Nontombi Marylucy; Osei Sekyere, John (Microbiology Society, 2020-11-10)Carbapenem-resistant Klebsiella pneumoniae (CRKP) remains a major clinical pathogen and public health threat with few therapeutic options. The mobilome, resistome, methylome, virulome and phylogeography of CRKP in South ...
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Mbelle, Nontombi Marylucy; Maningi, Nontuthuko Excellent; Tshisevhe, V.S.; Modipane, Lesedi; Amoako, Daniel Gyamfi; Sekyere, John Osei (American Society for Microbiology, 2017-12-14)Enterococcus faecalis is a lactic acid-producing Gram-positive bacterium commonly found in the intestinal tract of humans and animals; it is implicated in multidrug-resistant nosocomial infections. The draft genome of ...
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Rule, Roxanne; Said, Mohamed; Mbelle, Nontombi Marylucy; Osei Sekyere, John (Elsevier, 2019-12)OBJECTIVES : The underlying resistance mechanism and phylogenetic relationship of a colistin-resistant Salmonella enterica serovar Enteritidis strain EC20120916 that resulted in fatal meningitis in an immunocompromised ...
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Mbelle, Nontombi Marylucy; Osei Sekyere, John; Amoako, Daniel Gyamfi; Maningi, Nontuthuko Excellent; Modipane, Lesedi; Essack, Sabiha Yusuf; Feldman, Charles (Wiley, 2020-02)Please read abstract in the article.
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Mbelle, Nontombi Marylucy; Osei Sekyere, John; Feldman, Charles; Maningi, Nontuthuko Excellent; Modipane, Lesedi; Essack, Sabiha Y. (Wiley, 2020-01)Morganella morganii is an opportunistic bacterial pathogen of the Enterobacteriaceae family that is occasionally isolated from clinical (animal and human) specimens with varying resistance profiles. Detailed genomic analyses ...
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Lowe, Michelle; Kock, Marleen M.; Coetzee, Jennifer; Hoosien, Ebrahim; Peirano, Gisele; Strydom, Kathy-Anne; Ehlers, Marthie Magdaleen; Mbelle, Nontombi Marylucy; Shashkina, Elena; Haslam, David B.; Dhawan, Puneet; Donnelly, Robert J.; Chen, Liang; Kreiswirth, Barry N.; Pitout, Johann D.D. (Centers for Disease Control and Prevention, 2019-04)Klebsiella pneumoniae sequence type (ST) 307 is an emerging global antimicrobial drug–resistant clone. We used whole-genome sequencing and PCR to characterize K. pneumoniae ST307 with oxacillinase (OXA) 181 carbapenemase ...
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Singh-Moodley, Ashika; Duse, Adriano; Naicker, Preneshni; Kularatne, Ranmini; Nana, Trusha; Lekalakala, Ruth; Mbelle, Nontombi Marylucy; Dawood, Halima; Swe Swe Han, Khine; Ramjathan, Praksha; Bhola, Prathna; Whitelaw, Andrew; Perovic, Olga (Journal of Infection in Developing Countries, 2018)INTRODUCTION : Antimicrobial resistant bacterial infections are widespread globally and increases in antimicrobial resistance presents a major threat to public health. Pseudomonas aeruginosa is an opportunistic ...
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Sibandze, Doctor B.; Magazi, Beki T.; Malinga, Lesibana Anthony; Maningi, Nontuthuko Excellent; Shey, Bong-Akee; Pasipanodya, Jotam G.; Mbelle, Nontombi Marylucy (BMC, 2020-07)BACKGROUND: There is a general dearth of information on extrapulmonary tuberculosis (EPTB). Here, we investigated Mycobacterium tuberculosis (Mtb) drug resistance and transmission patterns in EPTB patients treated in the ...
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Chipolombwe, John; Torok, Mili Estee; Mbelle, Nontombi Marylucy; Nyasulu, Peter S. (Dove Medical Press, 2016-02-12)PURPOSE : The objective of this study was to evaluate the optimal number of sampling sites for detection of methicillin-resistant Staphylococcus aureus (MRSA) colonization. METHODS : We performed a Medline search from ...
Now showing items 1-20 of 32