Antimicrobial susceptibility patterns of selected bacteraemic isolates from South African public sector hospitals, 2010

Loading...
Thumbnail Image

Date

Authors

Bamford, Colleen
Bonorchis, Kim
Ryan, Anthea
Simpson, John
Elliott, Eugenne
Hoffmann, Rena
Naicker, Preneshni
Ismail, Nazir Ahmed
Mbelle, Nontombi Marylucy
Nchabeleng, Maphoshane

Journal Title

Journal ISSN

Volume Title

Publisher

Federation of Infectious Diseases Societies of South Africa

Abstract

We report on antimicrobial susceptibility surveillance data for six key bloodstream pathogens (Escherichia coli, Klebsiella pneumoniae, Enterobacter spp., Pseudomonas aeruginosa, Acinetobacter baumannii and Staphylococcus aureus) identified in public sector hospitals in South Africa during 2010. Major findings include the accelerated emergence of carbapenem resistance among K. pneumoniae and Enterobacter species, with overall susceptibility rates of 98% and 96% for ertapenem, and above 99% for meropenem and imipenem. Levels of resistance among P. aeruginosa and A. baumannii remain high in all centres, with few changes since 2009. Large decreases in piperacillin-tazobactam susceptibility rates were noted at three institutions, probably related to methodological issues. S. aureus remains a major pathogen countrywide, with between 30-60% of isolates resistant to cloxacillin [methicillin-resistant S. aureus (MRSA)]. Ongoing surveillance for antimicrobial resistance is vital, and the use of a centralised data extraction system may aid in this.

Description

Keywords

Surveillance, Antimicrobial resistance, Bacteraemia, Carbapenem resistance, South Africa, Public sector

Sustainable Development Goals

Citation

Bamford, C, Bonorchis, K, Ryan, A, Simpson, J, Elliott, E, Hoffmann, R, Naicker, P & Ismail, NA 2011, 'Antimicrobial susceptibility patterns of selected bacteraemic isolates from South African public sector hospitals, 2010', Southern African Journal of Epidemiology & Infection, vol. 26, no. 4, pp. 243-250.