Browsing Research Articles (Medical Microbiology) by Title

Browsing Research Articles (Medical Microbiology) by Title

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  • Tackling antimicrobial resistance in lower urinary tract infections : treatment options 
    Pitout, Johann D.D.; Chan, Wilson; Church, Deirdre L. (Taylor and Francis, 2016-07)
    Urinary tract infections (UTIs) are among the most common infectious diseases occurring in either the community or healthcare settings. A wide variety of bacteria are responsible for causing UTIs, however extra-intestinal ...
  • Towards early inclusion of children in tuberculosis drugs trials : a consensus statement 
    Nachman, Sharon; Ahmed, Amina; Amanullah, Farhana; Becerra, Mercedes C.; Botgros, Radu; Brigden, Grania; Browning, Renee; Gardiner, Elizabeth; Hafner, Richard; Hesseling, Anneke; How, Cleotilde; Jean-Philippe, Patrick; Lessem, Erica; Makhene, Mamodikoe; Mbelle, Nontombi Marylucy; Marais, Ben; McIlleron, Helen; McNeeley, David F.; Mendel, Carl; Murray, Stephen; Navarro, Eileen; Anyalechi, E. Gloria; Porcalla, Ariel R.; Powell, Clydette; Powell, Mair; Rigaud, Mona; Rouzier, Vanessa; Samson, Pearl; Schaaf, H. Simon; Shah, Seema; Starke, Jeff; Swaminathan, Soumya; Wobudeya, Eric; Worrell, Carol (Elsevier, 2015-06)
    Children younger than 18 years account for a substantial proportion of patients with tuberculosis worldwide. Available treatments for paediatric drug-susceptible and drug-resistant tuberculosis, albeit generally eff ective, ...
  • Treatment outcomes among children, adolescents, and adults on treatment for tuberculosis in two metropolitan municipalities in Gauteng Province, South Africa 
    Berry, Kaitlyn M.; Rodriguez, Carly A.; Berhanu, Rebecca H.; Ismail, Nazir Ahmed; Mvusi, Lindiwe; Long, Lawrence; Evans, Denise (BioMed Central, 2019-07-22)
    BACKGROUND : Gauteng Province has the second lowest tuberculosis (TB) incidence rate in South Africa but the greatest proportion of TB/HIV co-infection, with 68% of TB patients estimated to have HIV. TB treatment outcomes are ...
  • Trends in population dynamics of Escherichia coli sequence type 131, Calgary, Alberta, Canada, 2006–2016 
    Peirano, Gisele; Lynch, T.; Finn, T.J.; De Vinney, R.; Pitout, Johann D.D.; Matsumara, Y.; Nobrega, D. (Centers for Disease Control and Prevention, 2020-12)
    Global expansion of antimicrobial drug–resistant Escherichia coli sequence type (ST) 131 is unrivaled among human bacteria. Understanding trends among ST131 clades will help with designing prevention strategies. We ...
  • Tryptophan catabolism reflects disease activity in human tuberculosis 
    Collins, Jeffrey M.; Siddiqa, Amnah; Jones, Dean P.; Liu, Ken; Kempker, Russell R.; Nizam, Azhar; Shah, N. Sarita; Ismail, Nazir Ahmed; Ouma, Samuel G.; Tukvadze, Nestani; Li, Shuzhao; Day, Cheryl L.; Rengarajan, Jyothi; Brust, James C.M.; Gandhi, Neel R.; Ernst, Joel D.; Blumberg, Henry M.; Ziegler, Thomas R. (American Society for Clinical Investigation, 2020-05-05)
    There is limited understanding of the role of host metabolism in the pathophysiology of human tuberculosis (TB). Using high-resolution metabolomics with an unbiased approach to metabolic pathway analysis, we discovered ...
  • Tuberculosis cure rates and the ETR.Net : investigating the quality of reporting treatment outcomes from primary healthcare facilities in Mpumalanga province, South Africa 
    Dreyer, Andries W.; Mbambo, D.; Machaba, M.; Oliphant, C.E.M.; Claassens, M.M. (BioMed Central, 2017-03-10)
    BACKGROUND : Tuberculosis control programs rely on accurate collection of routine surveillance data to inform program decisions including resource allocation and specific interventions. The electronic TB register (ETR.Net) ...
  • Tuberculous pericarditis is multibacillary and bacterial burden drives high mortality 
    Pasipanodya, Jotam G.; Mubanga, Mwenya; Ntsekhe, Mpiko; Pandie, Shaheen; Magazi, Beki T.; Gumedze, Freedom; Myer, Landon; Gumbo, Tawanda; Mayosi, Bongani M. (Elsevier, 2015-11)
    BACKGROUND : Tuberculous pericarditis is considered to be a paucibacillary process; the large pericardial fluid accumulation is attributed to an inflammatory response to tuberculoproteins.Mortality rates are high. ...
  • Understanding antimicrobial discovery and resistance from a metagenomic and metatranscriptomic perspective : advances and applications 
    Asante, Jonathan; Osei Sekyere, John (Wiley, 2019-04)
    Our inability to cultivate most micro‐organisms, specifically bacteria, in the laboratory has for many years restricted our view and understanding of the bacterial meta‐resistome in all living and non‐living environments. ...
  • Understanding health worker data use in a South African antiretroviral therapy register 
    Jobson, Geoffrey A.; Murphy, Joshua; Van Huyssteen, Mea; Myburgh, Hanlie; Hurter, Theunis; Grobbelaar, Cornelis J.; Struthers, Helen E.; McIntyre, James A.; Peters, Remco P.H. (Wiley, 2018-09)
    OBJECTIVE : To evaluate how electronic data management systems affect data use practices in antiretroviral therapy (ART) programs within local health districts, and individual health facilities. METHODS : We used a data ...
  • Validation of bedaquiline phenotypic drug susceptibility testing methods and breakpoints : a multilaboratory, multicountry study 
    Kaniga, Koné; Aono, Akio; Borroni, Emanuele; Cirillo, Daniela Maria; Desmaretz, Christel; Hasan, Rumina; Joseph, Lavania; Mitarai, Satoshi; Shakoor, Sadia; Torrea, Gabriela; Ismail, Nazir Ahmed; Omar, Shaheed Vally (American Society for Microbiology, 2020-04)
    Drug-resistant tuberculosis persists as a major public health concern. Alongside efficacious treatments, validated and standardized drug susceptibility testing (DST) is required to improve patient care. This multicountry, ...
  • Viral hepatitis 
    Brink, Delene (Medpharm Publications, 2006-09)
    The hepatitis A, B, C, D and E viruses primarily target the liver to cause viral hepatitis. Hepatitis A (HAV) and E (HEV) viruses are transmitted by the faecal-oral route and cause acute viral hepatitis. Acute viral hepatitis ...
  • Vulvovaginal yeast infections during pregnancy and perinatal outcomes : systematic review and meta-analysis 
    Gigi, Ranjana M. S.; Buitrago‑Garcia, Diana; Taghavi, Katayoun; Dunaiski, Cara‑Mia; Van de Wijgert, Janneke H.H.M.; Peters, Remco P.H.; Low, Nicola (BMC, 2023-03-21)
    BACKGROUND : Vulvovaginal yeast infections in pregnancy are common and can cause extensive inflammation, which could contribute to adverse pregnancy outcomes. Symptomatic yeast infections are likely to cause more ...
  • WASH infrastructure and practices in primary health care clinics in the rural Vhembe district municipality in South Africa 
    Potgieter, N.; Banda, N.T.; Becker, Piet J.; Traore-Hoffman, A.N. (BMC, 2021-01)
    BACKGROUND: South Africa has unique and diverse social and economic factors that have an impact on the provision of basic water, sanitation, hygiene and waste management infrastructure and practices at health care facilities ...
  • Weight change among women using intramuscular depot medroxyprogesterone acetate, a copper intrauterine device, or a levonorgestrel implant for contraception : findings from a randomised, multicentre, open-label trial 
    Beksinska, Mags; Issema, Rodal; Beesham, Ivana; Lalbahadur, Tharnija; Thomas, Katherine; Morrison, Charles; Hofmeyr, G. Justus; Steyn, Petrus S.; Mugo, Nelly; Palanee-Phillips, Thesla; Ahmed, Khatija; Nair, Gonasagrie; Baeten, Jared M.; Smit, Jenni (Elsevier, 2021-04)
    BACKGROUND : There is limited evidence on the impact of the use of progestin-only hormonal contraception (POC) on weight change. We conducted a secondary analysis of prospective weight change among women enrolled in the ...
  • Whole genome sequencing for drug resistance determination in Mycobacterium tuberculosis 
    Omar, Shaheed Vally; Joseph, Lavania; Halima M. Said; Ismail, Farzana; Ismail, Nabila; Gwala, Thabisile L.; Ismail, Nazir Ahmed (AOSIS Open Journals, 2019-02-21)
    South Africa remains challenged with a high tuberculosis burden accompanied by an increase in drug resistant cases. We assessed the use of the Illumina MiSeq, a next-generation sequencing platform for whole genome ...
  • Whole-genome sequence of a Mycobacterium goodii isolate from a pediatric patient in South Africa 
    Allam, Mushal; Joseph, Lavania; Ismail, Farzana; Said, Halima; Ismail, Nazir Ahmed; Ismail, Arshad; Mtshali, Senzo; Mnyameni, Florah; Goussard, Pierre; Pekeur, Jade C.; Lourens, Adre; Omar, Shaheed Vally (American Society for Microbiology, 2018-01-18)
    We describe here the draft genome sequence of a Mycobacterium goodii isolate from a pediatric patient in Western Cape, South Africa. To our knowledge, this is the second reported genome of this rapidly growing nontuberculous ...
  • Whole-genome sequencing for prediction of Mycobacterium tuberculosis drug susceptibility and resistance : a retrospective cohort study 
    Ismail, Nazir Ahmed; Omar, Shaheed Vally; Walker, Timothy M.; Kohl, Thomas A.; Hedge, Jessica; Elias, Carlos Del Ojo; Bradley, Phelim; Iqbal, Zamin; Feuerriegel, Silke; Niehaus, Katherine E.; Wilson, Daniel J.; Clifton, David A.; Kapatai, Georgia; Ip, Camilla L.C.; Bowden, Rory; Drobniewski, Francis A.; Allix-Béguec, Caroline; Gaudin, Cyril; Parkhill, Julian; Diel, Roland; Supply, Philip; Crook, Derrick W.; Smith, E. Grace; Walker, A. Sarah; Niemann, Stefan; Peto, Tim E. A.; Davies, J.; Crichton, C.; Acharya, M.; Madrid-Marquez, Eyre, D.; Wyllie, D.; Golubchik, T.; Munang, M. (Elsevier, 2015-10)
    BACKGROUND : Diagnosing drug-resistance remains an obstacle to the elimination of tuberculosis. Phenotypic drugsusceptibility testing is slow and expensive, and commercial genotypic assays screen only common resistanced ...