Browsing Research Articles (Medical Virology) by Author "Williams, June Heather"

Browsing Research Articles (Medical Virology) by Author "Williams, June Heather"

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  • Comparative pathology of neurovirulent lineage 1 (NY99/385) and lineage 2 (SPU93/01) West Nile virus Infections in BALBc mice 
    Williams, June Heather; Mentoor, Juliet Lewie Dionee; Van Wilpe, Erna; Venter, Marietjie (Sage, 2015-01)
    The pathology in mice infected with neurovirulent South African lineage 2 West Nile virus (WNV) strains has not previously been described. Three- to 4-month-old male BALBc mice were infected with South African neurovirulent ...
  • Epidemiology and genomic analysis of equine encephalosis virus detected in horses with clinical signs in South Africa, 2010-2017 
    Snyman, Jumari; Koekemoer, Otto; Van Schalkwyk, Antoinette; Van Vuren, Petrus Jansen; Snyman, Louwtjie P.; Williams, June Heather; Venter, Marietjie (MDPI, 2021-03)
    Equine encephalosis virus (EEV) is a neglected virus endemic to South Africa and is considered to generally result in mild disease in equines. Specimens were analyzed from live horses that presented with undefined ...
  • Epidemiology of Shuni virus in horses in South Africa 
    Motlou, Thopisang; Williams, June Heather; Venter, Marietjie (MDPI, 2021-05-19)
    The Orthobunyavirus genus, family Peribunyaviridae, contains several important emerging and re-emerging arboviruses of veterinary and medical importance. These viruses may cause mild febrile illness, to severe encephalitis, ...
  • Fatal neurologic disease and abortion in mare infected with lineage 1 West Nile virus, South Africa 
    Venter, Marietjie; Human, Stacey; Van Niekerk, Stephanie; Williams, June Heather; Van Eeden, Charmaine; Freeman, Frank (Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention, 2011-08)
    In 2010, lineage 1 West Nile virus was detected in South Africa in the brain of a pregnant mare that succumbed to neurologic disease and in her aborted fetus, suggesting an association with abortion in horses. All West ...
  • Lineage 2 West Nile virus as cause of fatal neurologic disease in horses, South Africa 
    Venter, Marietjie; Human, Stacey; Zaayman, Dewald; Gerdes, Gertruida Hermanna; Williams, June Heather; Steyl, Johan Christian Abraham; Leman, Patricia A.; Paweska, Janusz Tadeusz; Setzkorn, Hildegard; Rous, Gavin; Murray, Sue; Parker, Rissa; Donnellan, Cynthia Mary Bridget; Swanepoel, Robert (Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention, 2009-05-06)
    Serologic evidence suggests that West Nile virus (WNV) is widely distributed in horses in Southern Africa. However, because few neurologic cases have been reported, endemic lineage 2 strains were postulated to be non-pathogenic ...
  • Pathology of fatal lineage 1 and 2 West Nile virus infections in horses in South Africa 
    Williams, June Heather; Van Niekerk, Stephanie; Human, Stacey; Van Wilpe, Erna; Venter, Marietjie (OpenJournals Publishing, 2014-09-10)
    Since 2007, West Nile virus (WNV) has been reported in South African horses, causing severe neurological signs. All cases were of lineage 2, except for one case that clustered with lineage 1 viruses. In the present study, ...
  • Sindbis and Middelburg old world alphaviruses associated with disease in horses, South Africa 
    Van Niekerk, Stephanie; Human, Stacey; Williams, June Heather; Van Wilpe, Erna; Pretorius, Marthi Andréa; Swanepoel, Robert; Venter, Marietjie (Centers for Disease Control & Prevention, 2015-12)
    Old World alphaviruses were identified in 52 of 623 horses with febrile or neurologic disease in South Africa. Five of 8 Sindbis virus infections were mild; 2 of 3 fatal cases involved co-infections. Of 44 Middelburg ...
  • West Nile virus in wildlife and nonequine domestic animals, South Africa, 2010–2018 
    Steyn, Jumari; Botha, Elizabeth; Stivaktas, Voula; Buss, Peter Erik; Beechler, Brianna R.; Myburgh, Jan G.; Steyl, Johan Christian Abraham; Williams, June Heather; Venter, Marietjie (Centers for Disease Control and Prevention, 2019-12)
    West Nile virus (WNV) lineage 2 is associated with neurologic disease in horses and humans in South Africa. Surveillance in wildlife and nonequine domestic species during 2010–2018 identified WNV in 11 (1.8%) of 608 animals ...
  • West Nile virus lineage 2 in horses and other animals with neurologic disease, South Africa, 2008-2015 
    Venter, Marietjie; Pretorius, Marthi Andréa; Fuller, James A.; Botha, Elizabeth; Rakgotho, Mpho; Stivaktas, Voula; Weyer, Camilla Theresa; Romito, Marco; Williams, June Heather (Centers for Disease Control and Prevention, 2017-12)
    During 2008–2015 in South Africa, we conducted West Nile virus surveillance in 1,407 animals with neurologic disease and identified mostly lineage 2 cases in horses (7.4%, 79/1,069), livestock (1.5%, 2/132), and wildlife ...
  • Zoonotic alphaviruses in fatal and neurologic infections in wildlife and nonequine domestic animals, South Africa 
    Steyn, Jumari; Fourie, Isabel; Steyl, Johan Christian Abraham; Williams, June Heather; Stivaktas, Voula; Botha, Elizabeth; Van Niekerk, Stephanie; Venter, Marietjie; Reininghaus, V. (Centers for Disease Control and Prevention, 2020-06)
    Alphaviruses from Africa, such as Middelburg virus (MIDV), and Sindbis virus (SINV), were detected in horses with neurologic disease in South Africa, but their host ranges remain unknown. We investigated the contribution of ...