Browsing Research Articles (Medical Virology) by Title

Browsing Research Articles (Medical Virology) by Title

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  • Quantification and molecular characterisation of human sapoviruses in water sources impacted by highly polluted discharged wastewater in South Africa 
    Murray, Tanya Y.; Taylor, Maureen B. (IWA Publishing, 2015-12)
    Sapoviruses (SaVs) were detected and quantified in 8/10 water samples collected from wastewater treatment works (WWTW) and water sources impacted by these WWTWs in Limpopo Province, South Africa. The median SaV concentration ...
  • Quantitative analysis of a urine-based assay for detection of lipoarabinomannan in patients with tuberculosis 
    Shah, Maunank; Martinson, Neil A.; Chaisson, Richard E.; Martin, Desmond J.; Variava, Ebrahim; Dorman, Susan E. (American Society for Microbiology, 2010-08)
    Urinary lipoarabinomannan (LAM) detection is a promising approach for rapid diagnosis of active tuberculosis (TB). In microbiologically confirmed TB patients, quantitative LAM detection results increased progressively with ...
  • Race in health research : considerations for researchers and research ethics committees 
    Van Staden, Werdie; Nienaber, A.; Rossouw, T.; Turner, A.C. (Astrid); Filmalter, Cecilia Jacoba; Nel, Jan Gert; Bapela, S.; Beetge, Mia-Michaela; Blumenthal, Ryan; Castelyn, Camille De Villebois; De Witt-Jordaan, T.W. (Wilma); Dlagnekova, Antonia; Kotze, Carla; Mangwane, S.; Napoles, Lizeka; Somers, R.; Sykes, Leanne M.; Van Zyl, W.B.; Venter, Marietjie; Uys, Andre; Warren, Nichola (South African Medical Association, 2023-04)
    This article provides ethical guidance on using race in health research as a variable or in defining the study population. To this end, a plain, non-exhaustive checklist is provided for researchers and research ethics ...
  • Rapid epidemic expansion of the SARS-CoV-2 Omicron variant in southern Africa 
    Viana, Raquel; Moyo, Sikhulile; Amoako, Daniel G.; Tegally, Houriiyah; Scheepers, Cathrine; Althaus, Christian L.; Anyaneji, Ugochukwu J.; Bester, Phillip A.; Boni, Maciej F.; Chand, Mohammed; Choga, Wonderful T.; Colquhoun, Rachel; Davids, Michaela; Deforche, Koen; Doolabh, Deelan; Du Plessis, Louis; Engelbrecht, Susan; Everatt, Josie; Giandhari, Jennifer; Giovanetti, Marta; Hardie, Diana; Hill, Verity; Hsiao, Nei-Yuan; Iranzadeh, Arash; Ismail, Arshad; Joseph, Charity; Joseph, Rageema; Koopile, Legodile; Pond, Sergei L. Kosakovsky; Kraemer, Moritz U.G.; Kuate-Lere, Lesego; Laguda-Akingba, Oluwakemi; Lesetedi-Mafoko, Onalethatha; Lessells, Richard; Lockman, Shahin; Lucaci, Alexander G.; Maharaj, Arisha; Mahlangu, Boitshoko; Maponga, Tongai; Mahlakwane, Kamela; Makatini, Zinhle; Marais, Gert; Maruapula, Dorcas; Masupu, Kereng; Matshaba, Mogomotsi; Mayaphi, Simnikiwe; Mbhele, Nokuzola; Mbulawa, Mpaphi B.; Mendes, Adriano; Mlisana, Koleka; Mnguni, Anele; Mohale, Thabo; Moir, Monika; Moruisi, Kgomotso; Mosepele, Mosepele; Motsatsi, Gerald; Motswaledi, Modisa S.; Mphoyakgosi, Thongbotho; Msomi, Nokukhanya; Mwangi, Peter N.; Naidoo, Yeshnee; Ntuli, Noxolo; Nyaga, Martin; Olubayo, Lucier; Pillay, Sureshnee; Radibe, Botshelo; Ramphal, Yajna; Ramphal, Upasana; San, James E.; Scott, Lesley; Shapiro, Roger; Smith-Lawrence, Pamela; Stevens, Wendy; Strydom, Amy; Subramoney, Kathleen; Tebeila, Naume; Tshiabuila, Derek; Tsui, Joseph; Van Wyk, Stephanie; Weaver, Steven; Wibmer, Constantinos K.; Wilkinson, Eduan; Wolter, Nicole; Zarebski, Alexander E.; Zuze, Boitumelo; Goedhals, Dominique; Preise, Wolfgang; Treurnicht, Florette; Venter, Marietjie; Williamson, Carolyn; Pybus, Oliver G.; Bhiman, Jinal; Glass, Allison; Martin, Darren P.; Rambaut, Andrew; Gaseitsiwe, Simani; Von Gottberg, Anne; De Oliveira, Tulio (Nature Research, 2022-03-24)
    The SARS-CoV-2 epidemic in southern Africa has been characterized by three distinct waves. The first was associated with a mix of SARS-CoV-2 lineages, while the second and third waves were driven by the Beta (B.1.351) ...
  • Rapid molecular strategy for filovirus detection and characterization 
    Zhai, Junhui; Palacios, Gustavo; Towner, Jonathan S.; Jabado, Omar; Kapoor, Vishal; Venter, Marietjie; Grolla, Allen; Briese, Thomas; Paweska, Janusz Tadeusz; Swanepoel, Robert; Feldmann, Heinz; Nichol, Stuart T.; Lipkin, Ian W. (American Society for Microbiology, 2007-01)
    Filoviruses have the capacity to cause lethal outbreaks of hemorrhagic fever in primates. Here we present a simple consensus reverse transcription-PCR method for filovirus recognition and characterization and demonstrate ...
  • Rapid reverse transcriptase recombinase polymerase amplification assay for flaviviruses using non-infectious in vitro transcribed RNA as positive controls 
    Bonnet, Elise; Van Jaarsveldt, Danelle; Burt, Felicity Jane (Elsevier, 2022-01)
    West Nile virus (WNV) and Wesselsbron virus (WSLV) are mosquito-borne viruses belonging to the Flavivirus genus, family Flaviviridae and cause outbreaks in southern Africa after heavy rain. Isothermal assays have been ...
  • Recommendations for the management of indeterminate HIV PCR results within South Africa’s early infant diagnosis programme 
    Mazanderani, Ahmad Haeri; Technau, Karl-Gunter; Hsiao, Nei-Yuan; Maritz, Jean; Carmona, Sergio; Sherman, Gayle G. (Health and Medical Publishing Group, 2016-05-13)
    Indeterminate HIV PCR results represent missed diagnostic opportunities within South Africa’s early infant diagnosis programme. These results not only delay diagnosis and appropriate management but are also a source of ...
  • Rediscovery of Haematobosca zuluensis (Zumpt), (Diptera, Stomoxyinae) : re-description and amended keys for the genus 
    Braack, L.E.O.; Pont, Adrian C. (BioMed Central, 2012-11-21)
    BACKGROUND: Prior to this publication, the biting fly Haematobosca zuluensis (Zumpt, 1950) (Diptera, Muscidae, Stomoxyinae) was known only from a single male specimen collected in 1923 in Zululand, South Africa. Seven ...
  • Reemergence of recombinant vaccine-derived poliovirus outbreak in Madagascar 
    Rakoto-Andrianarivelo, Mala; Gumede, Nicksy; Jegouic, Sophie; Balanant, Jean; Andriamamonjy, Seta N.; Rabemanantsoa, Sendraharimanana; Birmingham, Maureen; Randriamanalina, Bakolalao; Nkolomoni, Léon; Venter, Marietjie; Schoub, Barry D.; Delpeyroux, Francis; Reynes, Jean-Marc (University of Chicago Press, 2008-05-15)
    Background. After the 2001–2002 poliomyelitis outbreak due to recombinant vaccine-derived polioviruses (VDPVs) in the Toliara province of Madagascar, another outbreak reoccurred in the same province in 2005. Methods. We ...
  • Replacement of neuraminidase inhibitor-susceptible influenza A(H1N1) with resistant phenotype in 2008 and circulation of susceptible influenza A and B viruses during 2009-2013, South Africa 
    Treurnicht, Florette K.; Buys, Amelia; Tempia, Stefano; Seleka, Mpho; Cohen, Adam L.; Walaza, Sibongile; Glass, Allison J.; Rossouw, Inez; McAnerney, Johanna; Blumberg, Lucille Hellen; Cohen, Cheryl; Venter, Marietjie (Wiley Open Access, 2019-01)
    BACKGROUND : Data on the susceptibility of influenza viruses from South Africa to neuraminidase inhibitors (NAIs) are scarce, and no extensive analysis was done. OBJECTIVES : We aimed to determine oseltamivir and zanamivir ...
  • Replacement of previously circulating respiratory syncytial virus subtype B strains with the BA genotype in South Africa 
    Van Niekerk, Stephanie; Venter, Marietjie (American Society for Microbiology, 2011-09)
    Respiratory Syncytial Virus (RSV) is a major cause of bronchiolitis and pneumonia in infants, immunocompromised and the elderly in both developed and developing countries. Re-infections are common and G protein variability ...
  • Respiratory viral coinfections identified by a 10-plex real-time reverse-transcription polymerase chain reaction assay in patients hospitalized with severe acute respiratory iIllness, South Africa, 2009–2010 
    Pretorius, Marthi Andréa; Madhi, Shabir A.; Cohen, Cheryl; Naidoo, Dhamari; Groome, Michelle; Moyes, Jocelyn; Buys, Amelia; Walaza, Sibongile; Dawood, Halima; Chhagan, Meera; Haffejee, Summaya; Kahn, Kathleen; Puren, Adrian; Venter, Marietjie (Oxford University Press, 2012)
    BACKGROUND: Data about respiratory co-infections of Influenza A H1N1 during the pandemic in Africa are limited. We used an existing surveillance programme for severe acute respiratory illness (SARI) to evaluate a new ...
  • Results from the WHO external quality assessment for the respiratory syncytial virus pilot, 2016-17 
    Jackson, Sandra; Peret, Teresa C. T.; Ziegler, Thedi T.; Thornburg, Natalie J.; Besselaar, Terry G.; Broor, Shobha; Barr, Ian; Baumeister, Elsa; Chadha, Mandeep; Chittaganpitch, Malinee; Darmaa, Badarch; Ellis, Joanna; Fasce, Rodrigo; Fasce, Rodrigo; Herring, Belinda; Herve, Kadjo; Hirve, Siddhivinayak; Li, Yan; Pisareva, Maria; Moen, Ann; Naguib, Amel; Palekar, Rakhee; Potdar, Varsha; Siqueira, Marilda; Treurnicht, Florette; Tivane, Almiro; Venter, Marietjie; Wairagkar, Niteen; Zambon, Maria; Zhang, Wenqing (Wiley Open Access, 2020)
    BACKGROUND : External quality assessments (EQAs) for the molecular detection of respiratory syncytial virus (RSV) are necessary to ensure the provision of reliable and accurate results. One of the objectives of the pilot ...
  • Reverse genetics system for shuni virus, an emerging orthobunyavirus with zoonotic potential 
    Oymans, Judith; Wichgers Schreur, Paul J.; Van Oort, Sophie; Vloet, Rianka; Venter, Marietjie; Pijlman, Gorben P.; Van Oers, Monique M.; Kortekaas, Jeroen (MDPI, 2020-04)
    The genus Orthobunyavirus (family Peribunyaviridae, order Bunyavirales) comprises over 170 named mosquito- and midge-borne viruses, several of which cause severe disease in animals or humans. Their three-segmented genomes ...
  • Reverse transcription recombinase polymerase amplification assay for rapid detection of canine associated rabies virus in Africa 
    Coertse, Jessica; Weyer, Jacqueline; Nel, Louis Hendrik; Markotter, Wanda (Public Library of Science, 2019-07)
    Rabies is a neglected disease mostly affecting the developing world. Accurate and reliable diagnostic and surveillance data forms the foundation for the formulation and monitoring of control strategies. Although various ...
  • Rift Valley fever in Kruger National Park : do buffalo play a role in the inter-epidemic circulation of virus? 
    Beechler, B.R.; Bengis, Roy G.; Swanepoel, Robert; Paweska, Janusz Tadeusz; Kemp, Alan; Jansen van Vuren, Petrus; Joubert, J.; Ezenwa, V.O.; Jolles, Anna E. (2015-02)
    Rift Valley fever (RVF) is a zoonotic mosquito-borne virus disease of livestock and wild ruminants that has been identified as a risk for international spread. Typically, the disease occurs in geographically limited ...
  • Risk factors for influenza-associated severe acute respiratory illness hospitalization in South Africa, 2012–2015 
    Tempia, Stefano; Walaza, Sibongile; Moyes, Jocelyn; Cohen, Adam L.; Von Mollendorf, Claire; Treurnicht, Florette K.; Venter, Marietjie; Pretorius, Marthi Andréa; Hellferscee, Orienka; Mtshali, Senzo; Seleka, Mpho; Tshangela, Akhona; Nguweneza, Athermon; McAnerney, Johanna M.; Wolter, Nicole; Von Gottberg, Anne; Dawood, Halima; Variava, Ebrahim; Madhi, Shabir A.; Cohen, Cheryl (Oxford University Press, 2017)
    BACKGROUND : Data on risk factors for influenza-associated hospitalizations in low- and middle-income countries are limited. METHODS : We conducted active syndromic surveillance for hospitalized severe acute respiratory ...
  • Risk factors for poor virological outcome at 12 months in a workplace-based antiretroviral therapy programme in South Africa : a cohort study 
    Fielding, Katherine L.; Charalambous, Salome; Stenson, Amy L.; Pemba, Lindiwe F.; Martin, Desmond J.; Wood, Robin; Churchyard, Gavin J.; Grant, Alison D. (BioMed Central, 2008-07)
    BACKGROUND: Reasons for the variation in reported treatment outcomes from antiretroviral therapy (ART) programmes in developing countries are not clearly defined. METHODS: Among ART-naïve individuals in a workplace ART ...
  • Risk for HIV-1 infection associated with a common CXCL12 (SDF1) polymorphism and CXCR4 variation in an African population 
    Petersen, Desiree C.; Glashoff, Richard H.; Sherestha, Sadeep; Bergeron, Julie; Laten, Anette; Gold, Bert; Janse van Rensburg, Estrelita; Dean, Michael; Hayes, Vanessa M. (Lippincott Williams and Wilkins, 2005-12-15)
    CXC chemokine ligand 12 (CXCL12), or stromal cell–derived factor 1 (SDF1), is the only known natural ligand for the HIV-1 coreceptor, CXC chemokine receptor 4 (CXCR4). A single nucleotide polymorphism (SNP) in the CXCL12 ...
  • Robust evidence for bats as reservoir hosts is lacking in most African virus studies : a review and call to optimize sampling and conserve bats 
    Weber, Natalie; Nagy, Martina; Markotter, Wanda; Schaer, Juliane; Puechmaille, Sebastien J.; Sutton, Jack; Davalos, Liliana M.; Dusabe, Marie-Claire; Ejotre, Imran; Fenton, M. Brock; Knornschild, Mirjam; Lopez-Baucells, Adria; Medellin, Rodrigo A.; Mubareka, Samira; Nsengimana, Olivier; O’Mara, M. Teague; Racey, Paul A.; Tuttle, Merlin; Twizeyimana, Innocent; Vicente-Santos, Amanda; Tschapka, Marco; Voigt, Christian C.; Wikelski, Martin; Dechmann, Dina K.N.; Reeder, DeeAnn M. (Royal Society, 2023-11)
    Africa experiences frequent emerging disease outbreaks among humans, with bats often proposed as zoonotic pathogen hosts. We comprehensively reviewed virus–bat findings from papers published between 1978 and 2020 to ...