Browsing Research Articles (Medical Virology) by Title

Browsing Research Articles (Medical Virology) by Title

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  • Serological evidence of lyssaviruses among bats on Southwestern Indian Ocean Islands 
    Melade, Julien; McCulloch, Stewart D.; Ramasindrazana, Beza; Lagadec, Erwan; Turpin, Magali; Pascalis, Herve; Goodman, Steven M.; Markotter, Wanda; Dellagi, Koussay (Public Library of Science, 2016-08-08)
    We provide serological evidence of lyssavirus circulation among bats on southwestern Indian Ocean (SWIO) islands. A total of 572 bats belonging to 22 species were collected on Anjouan, Mayotte, La Réunion, Mauritius, ...
  • Seroprevalence of Crimean Congo hemorrhagic fever virus in Ijara District, Kenya 
    Lwande, Olivia Wesula; Irura, Zephania; Tigoi, Caroline; Chepkorir, Edith; Orindi, Benedict; Musila, Lillian; Venter, Marietjie; Fischer, Anne; Sang, Rosemary (Mary Ann Liebert, 2012)
    Crimean-Congo hemorrhagic fever (CCHF) is a tick-borne viral disease mainly affecting pastoralists who come in contact with animals infested with Hyalomma ticks, which are the key vectors of CCHF virus (CCHFV). CCHFV has ...
  • Serum neutralising antibody response of seronegative horses against lineage 1 and lineage 2 West Nile virus following vaccination with an inactivated lineage 1 West Nile virus vaccine 
    Pearce, Michael C.; Venter, Marietjie; Schouwstra, Tjitske; Van Eeden, Charmaine; Jansen van Vuren, Petrus; Paweska, Janusz Tadeusz; Liu, Bo; Du Plessis, Arrie (OpenJournals Publishing, 2013-11-21)
    Lineage 2 West Nile virus (WNV) strains are endemic in South Africa and cause severe neurological disease in horses. An inactivated lineage 1 vaccine, Duvaxyn WNV, protects mice against challenge with a neuroinvasive South ...
  • Severe influenza-associated respiratory infection in high HIV prevalence setting, South Africa, 2009-2011 
    Cohen, Cheryl; Moyes, Jocelyn; Tempia, Stefano; Groome, Michelle; Walaza, Sibongile; Pretorius, Marthi Andréa; Dawood, Halima; Chhagan, Meera; Haffejee, Summaya; Variava, Ebrahim; Kahn, Kathleen; Tshangela, Akhona; Von Gottberg, Anne; Wolter, Nicole; Cohen, Adam L.; Kgokong, Babatyi; Venter, Marietjie; Madhi, Shabir A. (Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention, 2013-11)
    Data on influenza epidemiology in HIV-infected persons are limited, particularly for sub-Saharan Africa, where HIV infection is widespread. We tested respiratory and blood samples from patients with acute lower respiratory ...
  • Severity of respiratory syncytial virus lower respiratory tract infection with viral coinfection in HIV-uninfected children 
    Mazur, Natalie I.; Bont, Louis; Cohen, Adam L.; Cohen, Cheryl; Von Gottberg, Anne; Groome, Michelle J.; Hellferscee, Orienka; Klipstein-Grobusch, Kerstin; Mekgoe, Omphile Tschegofatso; Naby, Fathima; Moyes, Jocelyn; Tempia, Stefano; Treurnicht, Florette K.; Venter, Marietjie; Walaza, Sibongile; Wolter, Nicole; Madhi, Shabir A. (Oxford University Press, 2017-02)
    BACKGROUND : Molecular diagnostics enable sensitive detection of respiratory viruses, but their clinical significance remains unclear in pediatric lower respiratory tract infection (LRTI). We aimed to determine whether ...
  • Shedding of Marburg virus in naturally infected Egyptian rousette bats, South Africa, 2017 
    Paweska, Janusz Tadeusz; Storm, N.; Markotter, Wanda; Di Paola, N.; Wiley, M.R.; Palacios, G.; Van Vuren, P.J. (Centers for Disease Control and Prevention, 2020-12)
    We detected Marburg virus RNA in rectal swab samples from Egyptian rousette bats in South Africa in 2017. This finding signifies that fecal contamination of natural bat habitats is a potential source of infection for ...
  • Short-term effectiveness and safety of HAART in the form of a generic fixed-dose combination of stavudine, lamivudine and nevirapine (Triviro) in HIV-1-infected adults in Zimbabwe 
    Duse, A.G.; Morar, A.; Landman, I.; Vermaak, William J.H.; Schoeman, H.; Kruger, M.J.; Janse van Rensburg, E.S. (Elsie); Luthy, R.; Singh, S. (Health and Medical Publishing Group, 2008)
    OBJECTIVES. To assess the effectiveness and safety of a twice-daily regimen of a generic fixed-dose combination (FDC) of stavudine, lamivudine and nevirapine (Triviro) in a cohort of Zimbabwean HIV-1-positive adults. DESIGN: ...
  • Shuni virus in cases of neurologic disease in humans, South Africa 
    Motlou, Thopisang; Venter, Marietjie (Coordinating Center for Infectious Diseases, Centers for Disease Control and Prevention, 2021-02)
    We describe Shuni virus (SHUV) detection in human neurologic disease cases in South Africa. SHUV RNA was identified in 5% of cerebrospinal fluid specimens collected during the arbovirus season from public sector hospitals. ...
  • Sindbis and Middelburg old world alphaviruses associated with disease in horses, South Africa 
    Van Niekerk, Stephanie; Human, Stacey; Williams, June Heather; Van Wilpe, Erna; Pretorius, Marthi Andréa; Swanepoel, Robert; Venter, Marietjie (Centers for Disease Control & Prevention, 2015-12)
    Old World alphaviruses were identified in 52 of 623 horses with febrile or neurologic disease in South Africa. Five of 8 Sindbis virus infections were mild; 2 of 3 fatal cases involved co-infections. Of 44 Middelburg ...
  • Spotted fever rickettsiosis in South Africa : evaluation of laboratory diagnostic capacity and inter-laboratory comparison of serological testing 
    Trataris-Rebisz, A.N.; Rossouw, J.; Markotter, Wanda; Frean, J.A.; Weyer, Jacqueline (Health and Medical Publishing Group, 2019-04)
    BACKGROUND. Spotted fever rickettsiosis, also known as tick bite fever (TBF), is a common infectious disease in South Africa (SA). Although the diagnosis of TBF is often based on clinical grounds only, laboratory testing ...
  • Staphylococcus aureus bacteraemia in Gauteng academic hospitals, South Africa 
    Fortuin-de Smidt, Melony C.; Singh-Moodley1, Ashika; Badat, Rubeina; Quan, Vanessa; Kularatne, Ranmini; Nana, Trusha; Lekalakala, M. Ruth; Govender, N.P. (Nelesh); Perovic, Olga (Elsevier (open access), 2015-01)
    INTRODUCTION : Methicillin-resistant Staphylococcus aureus (MRSA) infections are responsible for longer hospital stays, increased hospital costs, and poorer outcomes compared to methicillin-sensitive S. aureus (MSSA) ...
  • Stem cell transplant in immune-deficiency-associated vaccine-derived poliovirus 
    Ranchod, Heena; Howard, Wayne; Roux, Adele; Van Zyl, Walda B.; Ekermans, Pieter; Van den Berg, Sylvia; Seakamela, Lerato; Makua, Koketso; Yousif, Mukhlid; Sibiya, Rosinah; Du Plessis, Heleen; Phalane, Emmanuel; McCarthy, Kerrigan; Moonsamy, Shelina; Reynders, David; Hincks, Jeffrey; Suchard, Melinda S.; Du Plessis, Nicolette Marie (Oxford University Press, 2024-01)
    Patients with severe primary immunodeficiency are at risk for complications from live-attenuated vaccines. Here, we report a case of a vaccine-associated paralytic polio and Bacille Calmette-Guérin disease in a 6-month-old ...
  • Structure and function of murine cytomegalovirus MHC-I-like molecules : how the virus turned the host defense to its advantage 
    Mans, Janet; Zhi, Li; Revilleza, Maria Jamela R.; Smith, Lee; Redwood, Alec; Natarajan, Kannan; Margulies, David H. (Springer, 2009)
    The mouse cytomegalovirus (CMV), a β-herpesvirus, exploits its large (~230 kb) double-stranded DNA genome for both essential and non-essential functions. Among the non-essential functions are those that offer the virus a ...
  • Studying the microbiota of bats: Accuracy of direct and indirect samplings 
    Dietrich, Muriel; Markotter, Wanda (Wiley Open Access, 2019-02)
    Given the recurrent bat‐associated disease outbreaks in humans and recent advances in metagenomics sequencing, the microbiota of bats is increasingly being studied. However, obtaining biological samples directly from ...
  • Surveillance of the rabies-relatedlyssavirus, Mokola in non-volant small mammals in South Africa 
    McMahon, William Charles; Coertse, Jessica; Kearney, Teresa; Keith, Mark; Swanepoel, Lourens H.; Markotter, Wanda (AOSIS, 2021-08)
    The reservoir host of Mokola virus (MOKV), a rabies-related lyssavirus species endemic to Africa, remains unknown. Only sporadic cases of MOKV have been reported since its first discovery in the late 1960s, which ...
  • Survey of West Nile and Banzi viruses in mosquitoes, South Africa, 2011–2018 
    MacIntyre, Caitlin; Guarido, Milenha M.; Riddin, Megan A.; Johnson, Todd; Braack, L.E.O.; Schrama, Maarten; Gorsich, Erin; Almeida, Antonio Paulo Gouveia; Venter, Marietjie (Centers for Disease Control and Prevention, 2023-01)
    We collected >40,000 mosquitoes from 5 provinces in South Africa during 2011–2018 and screened for zoonotic flaviviruses. We detected West Nile virus in mosquitoes from conservation and periurban sites and potential new ...
  • Synchronized shift of oral, faecal and urinary microbiotas in bats and natural infection dynamics during seasonal reproduction 
    Dietrich, Muriel; Kearney, Teresa; Seamark, E.C.J. (Ernest); Paweska, Janusz Tadeusz; Markotter, Wanda (Royal Society Publishing, 2018)
    Seasonal reproduction is a period of extreme physiological and behavioural changes, yet we know little about how it may affect host microbial communities (i.e. microbiota) and pathogen transmission. Here, we investigated ...
  • A systematic review on mobile health applications for foodborne disease outbreak management 
    Ntshoe, Genevie M.; Shonhiwa, Andronica Moipone; Govender, Nevashan; Page, Nicola Anne (BioMed Central, 2021-12-08)
    BACKGROUND : Foodborne disease outbreaks are common and notifiable in South Africa; however, they are rarely reported and poorly investigated. Surveillance data from the notification system is suboptimal and limited, and ...
  • Taxonomy of the family Arenaviridae and the order Bunyavirales : update 2018 
    Maes, Piet; Alkhovsky, Sergey V.; Bào, Yīmíng; Beer, Martin; Birkhead, Monica; Briese, Thomas; Buchmeier, Michael J.; Calisher, Charles H.; Charrel, Rémi N.; Choi, Il Ryong; Clegg, Christopher S.; De la Torre, Juan Carlos; Delwart, Eric; DeRisi, Joseph L.; Di Bello, Patrick L.; Di Serio, Francesco; Digiaro, Michele; Dolja, Valerian V.; Drosten, Christian; Druciarek, Tobiasz Z.; Du, Jiang; Ebihara, Hideki; Elbeaino, Toufic; Gergerich, Rose C.; Gillis, Amethyst N.; Gonzalez, Jean-Paul J.; Haenni, Anne-Lise; Hepojoki, Jussi; Hetzel, Udo; Hồ, Thiện; Hóng, Ní; Jain, Rakesh K.; Jansen van Vuren, Petrus; Jin, Qi; Jonson, Miranda Gilda; Junglen, Sandra; Keller, Karen E.; Kemp, Alan; Kipar, Anja; Kondov, Nikola O.; Koonin, Eugene V.; Kormelink, Richard; Korzyukov, Yegor; Krupovic, Mart; Lambert, Amy J.; Laney, Alma G.; LeBreton, Matthew; Lukashevich, Igor S.; Marklewitz, Marco; Markotter, Wanda; Martelli, Giovanni P.; Martin, Robert R.; Mielke-Ehret, Nicole; Mühlbach, Hans-Peter; Navarro, Beatriz; Ng, Terry Fei Fan; Nunes, Márcio Roberto Teixeira; Palacios, Gustavo; Paweska, Janusz Tadeusz; Peters, Clarence J.; Plyusnin, Alexander; Radoshitzky, Sheli R.; Romanowski, Víctor; Salmenperä, Pertteli; Salvato, Maria S.; Sanfaçon, Hélène; Sasaya, Takahide; Schmaljohn, Connie; Schneider, Bradley S.; Shirako, Yukio; Siddell, Stuart; Sironen, Tarja A.; Stenglein, Mark D.; Storm, Nadia; Sudini, Harikishan; Tesh, Robert B.; Tzanetakis, Ioannis E.; Uppala, Mangala; Vapalahti, Olli; Vasilakis, Nikos; Walker, Peter J.; Wáng, Guópíng; Wáng, Lìpíng; Wáng, Yànxiăng; Wèi, Tàiyún; Wiley, Michael R.; Wolf, Yuri I.; Wolfe, Nathan D.; Wú, Zhìqiáng; Xú, Wénxìng; Yang, Li; Yāng, Zuòkūn; Yeh, Shyi-Dong; Zhāng, Yǒng-Zhèn; Zhèng, Yàzhōu; Zhou, Xueping; Zhū, Chénxī; Zirkel, Florian; Kuhn, Jens H. (Springer, 2018-08)
    In 2018, the family Arenaviridae was expanded by inclusion of 1 new genus and 5 novel species. At the same time, the recently established order Bunyavirales was expanded by 3 species. This article presents the updated ...
  • Taxonomy of the order Bunyavirales : second update 2018 
    Maes, Piet; Adkins, Scott; Alkhovsky, Sergey V.; Avšič-Županc, Tatjana; Ballinger, Matthew J.; Bente, Dennis A.; Beer, Martin; Bergeron, Éric; Blair, Carol D.; Briese, Thomas; Buchmeier, Michael J.; Burt, Felicity J.; Calisher, Charles H.; Charrel, Rémi N.; Choi, Il Ryong; Clegg, J. Christopher S.; De la Torre, Juan Carlos; De Lamballerie, Xavier; DeRisi, Joseph L.; Digiaro, Michele; Drebot, Mike; Ebihara, Hideki; Elbeaino, Toufic; Ergünay, Koray; Fulhorst, Charles F.; Garrison, Aura R.; Gāo, George Fú; Gonzalez, Jean-Paul J.; Groschup, Martin H.; Günther, Stephan; Haenni, Anne-Lise; Hall, Roy A.; Hewson, Roger; Hughes, Holly R.; Jain, Rakesh K.; Jonson, Miranda Gilda; Junglen, Sandra; Klempa, Boris; Klingström, Jonas; Kormelink, Richard; Lambert, Amy J.; Langevin, Stanley A.; Lukashevich, Igor S.; Marklewitz, Marco; Martelli, Giovanni P.; Mielke-Ehret, Nicole; Mirazimi, Ali; Mühlbach, Hans-Peter; Naidu, Rayapati; Nunes, Márcio Roberto Teixeira; Palacios, Gustavo; Papa, Anna; Paweska, Janusz Tadeusz; Peters, Clarence J.; Plyusnin, Alexander; Radoshitzky, Sheli R.; Resende, Renato O.; Romanowski, Víctor; Sall, Amadou Alpha; Salvato, Maria S.; Sasaya, Takahide; Schmaljohn, Connie; Shí, Xiǎohóng; Shirako, Yukio; Simmonds, Peter; Sironi, Manuela; Song, Jin-Won; Spengler, Jessica R.; Stenglein, Mark D.; Tesh, Robert B.; Turina, Massimo; Wèi, Tàiyún; Whitfield, Anna E.; Yeh, Shyi-Dong; Zerbini, F. Murilo; Zhang, Yong-Zhen; Zhou, Xueping; Kuhn, Jens H. (Springer, 2019-03)
    In October 2018, the order Bunyavirales was amended by inclusion of the family Arenaviridae, abolishment of three families, creation of three new families, 19 new genera, and 14 new species, and renaming of three genera ...