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Browsing Health Sciences by UP Author "Pitout, Johann D.D."
Now showing items 1-20 of 34
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Lowe, Michelle; Ehlers, Marthie Magdaleen; Ismail, Farzana; Peirano, Gisele; Becker, Piet J.; Pitout, Johann D.D.; Kock, Marleen M. (Frontiers Media, 2018-06-12)Acinetobacter baumannii is an opportunistic pathogen that is increasingly responsible for hospital-acquired infections. The increasing prevalence of carbapenem resistant A. baumannii has left clinicians with limited ...
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Carbapenemase-producing Klebsiella pneumoniae : a key pathogen set for global nosocomial dominance Pitout, Johann D.D.; Nordmann, Patrice; Poirel, Laurent (American Society for Microbiology, 2015-10)The management of infections due to Klebsiella pneumoniae has been complicated by the emergence of antimicrobial resistance, especially to the carbapenems. Resistance to the carbapenems in K. pneumoniae involves multiple ...
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Peirano, G.; Castellanos, L. Ricardo; Matsumura, Yasufumi; Chaffee, Ryan; Castaneda-Mogollon, Daniel; Pillai, Dylan R.; Pitout, Johann D.D. (American Society for Microbiology, 2024-03)The dissemination of Escherichia coli multidrug-resistant (MDR) STc131 is related to its persistence in the human gastrointestinal tract as efficient gut colonizers. Infection and prevention measures are the cornerstones ...
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Mataseje, L.F.; Peirano, Gisele; Church, Deirdre L.; Conly, J.; Mulvey, M.; Pitout, Johann D.D. (American Society for Microbiology, 2016-03)This study describes 3 different blaNDM-1 genetic platforms in 3 different species obtained from the same patient who was directly transferred to an institution in Calgary, Canada, following a prolonged hospital stay in ...
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Matsumura, Yasufumi; Peirano, Gisele; Pitout, Johann D.D. (American Society for Microbiology, 2018-05-24)We report here the complete genome sequence of Escherichia coli J53, which is used as a recipient in conjugation experiments and is a laboratory strain derived from E. coli K-12. This genome sequence will help in the ...
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Peirano, Gisele; Chen, Liang; Kreiswirth, Barry N.; Pitout, Johann D.D. (American Society for Microbiology, 2020-09)There is an enormous global public health burden due to antimicrobial-resistant (AMR) Klebsiella pneumoniae high-risk clones. K. pneumoniae ST307 and ST147 are recent additions to the family of successful clones in the ...
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Nobrega, Diego; Peirano, Gisele; Pitout, Johann D.D. (Springer, 2022-12)PURPOSE : Extraintestinal pathogenic E. coli (ExPEC) are important pathogens causing community-acquired infections in humans, including bloodstream infections (BSIs), and may also colonize and infect animals. Our aim was ...
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Jung, Hyunsul; Pitout, Johann D.D.; Mitton, Barend C.; Strydom, Kathy-Anne; Kingsburgh, Chanel; Coetzee, Jennifer; Ehlers, Marthie Magdaleen; Kock, Marleen M. (Microbiology Society, 2021-06)INTRODUCTION : Colistin is one of the last-resort antibiotics for treating multidrug-resistant (MDR) or extensively drug-resistant (XDR) lactose non-fermenting Gram-negative bacteria such as Pseudomonas aeruginosa and ...
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Pitout, Johann D.D.; Finn, Thomas J. (Elsevier, 2020-07)The abrupt expansion of Escherichia coli sequence type (ST) 131 is unmatched among Gram negative bacteria. In many ways, ST131 can be considered a real-world model for the complexities involved in the evolution of a multidrug ...
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Takawira, Faustinos Tatenda; Pitout, Johann D.D.; Thilliez, Gaetan; Mashe, Tapfumanei; Gutierrez, Ana Victoria; Kingsley, Robert A.; Peirano, Gisele; Matheu, Jorge; Midzi, Stanley Munyaradzi; Mwamakamba, Lusubilo Witson; Gally, David L.; Tarupiwa, Andrew; Mukavhi, Leckson; Ehlers, M.M. (Marthie Magdaleen); Mtapuri-Zinyowera, Sekesai; Kock, Marleen M. (Frontiers Media, 2022-12-23)INTRODUCTION : Extended spectrum beta-lactamase (ESBL) producing Escherichia coli have become widespread among food producing animals. These strains serve as a reservoir of antibiotic resistance genes (ARGs) and act as ...
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Stoesser, Nicole; Sheppard, Anna E.; Peirano, Gisele; Sebra, Robert; Lynch, Tarah; Anson, Luke; Kasarskis, Andrew; Motyl, Mary R.; Crook, Derrick W.; Pitout, Johann D.D. (American Society for Microbiology, 2016-08)The blaIMP-14 carbapenem resistance gene has largely previously been observed in Pseudomonas aeruginosa and Acinetobacter spp. As part of global surveillance and sequencing of carbapenem-resistant E. coli, we identified ...
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Peirano, Gisele; Chen, Liang; Nobrega, Diego; Finn, Thomas J. (Centers for Disease Control and Prevention, 2022-05)We describe the global molecular epidemiology of 229 carbapenemase-producing Escherichia coli in 36 countries during 2015–2017. Common carbapenemases were oxacillinase (OXA) 181 (23%), New Delhi metallo-β-lactamase (NDM) ...
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Genomic epidemiology of global Klebsiella pneumoniae carbapenemase (KPC)-producing Escherichia coli Stoesser, N.; Sheppard, A.E.; Peirano, Gisele; Anson, L.W.; Pankhurst, L.; Sebra, R.; Phan, H.T.T.; Kasarskis, A.; Mathers, A.J.; Peto, T.E.A.; Bradford, P.; Motyl, M.R.; Walker, A.S.; Crook, D.W.; Pitout, Johann D.D. (Nature Publishing Group, 2017-07-19)The dissemination of carbapenem resistance in Escherichia coli has major implications for the management of common infections. blaKPC, encoding a transmissible carbapenemase (KPC), has historically largely been associated ...
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Matsumura, Yasufumi; Peirano, Gisele; Devinney, Rebekah; Bradford, Patricia A.; Motyl, Mary R.; Adams, Mark D.; Chen, Liang; Kreiswirth, Barry; Pitout, Johann D.D. (Oxford University Press, 2017-08)BACKGROUND : International data on the molecular epidemiology of Enterobacteriaceae with VIM carbapenemases are limited. METHODS : We performed short read (Illumina) WGS on a global collection of 89 VIM-producing clinical ...
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Matsumura, Yasufumi; Peirano, Gisele; Motyl, Mary R.; Adams, Mark D.; Chen, Liang; Kreiswirth, Barry; DeVinney, Rebekah; Pitout, Johann D.D. (American Society for Microbiology, 2017-04)International data on the molecular epidemiology of Enterobacteriaceae with IMP carbapenemases are lacking. We performed short read (Illumina) whole genomic sequencing on a global collection of 38 IMP-producing clinical ...
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Peirano, Gisele; Bradford, Patricia A.; Kazmierczak, Krystyna M.; Chen, Liang; Kreiswirth, Barry N.; Pitout, Johann D.D. (American Society for Microbiology, 2017-04)Please read abstract in the article.
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Seni, Jeremiah; Peirano, Gisele; Mshana, Stephen E.; Pitout, Johann D.D.; DeVinney, Rebekah (Springer, 2023)Please read abstract in the article.
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Dingle, Tanis; Pitout, Johann D.D. (Journal of Clinical Microbiology, 2022-07)Ceftazidime-avibactam, meropenem-vaborbactam, and imipenem-relebactam are among the newest b-lactam/b-lactamase inhibitors (BL/BLIs) introduced to the North American antibiotic market. All have broad Gram-negative activity, ...
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Mataseje, L.F.; Chen, L.; Peirano, Gisele; Fakharuddin, K.; Kreiswith, B.; Mulvey, M.; Pitout, Johann D.D. (Springer, 2022-12)Please read abstract in the article.
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Lowe, Michelle; Kock, Marleen M.; Coetzee, Jennifer; Hoosien, Ebrahim; Peirano, Gisele; Strydom, Kathy-Anne; Ehlers, Marthie Magdaleen; Mbelle, Nontombi Marylucy; Shashkina, Elena; Haslam, David B.; Dhawan, Puneet; Donnelly, Robert J.; Chen, Liang; Kreiswirth, Barry N.; Pitout, Johann D.D. (Centers for Disease Control and Prevention, 2019-04)Klebsiella pneumoniae sequence type (ST) 307 is an emerging global antimicrobial drug–resistant clone. We used whole-genome sequencing and PCR to characterize K. pneumoniae ST307 with oxacillinase (OXA) 181 carbapenemase ...
Now showing items 1-20 of 34