The blaIMP-14 carbapenem resistance gene has largely previously been observed in
Pseudomonas aeruginosa and Acinetobacter spp. As part of global surveillance and
sequencing of carbapenem-resistant E. coli, we identified an ST131 strain harboring
blaIMP-14 within a class 1 integron, itself nested within a ~54kb multi-drug resistance
region on an epidemic IncA/C2 plasmid. The emergence of blaIMP-14 in this context in
the ST131 lineage is of potential clinical concern.