First report of blaIMP-14 on a plasmid harboring multiple drug resistance genes in Escherichia coli sequence type 131

dc.contributor.authorStoesser, Nicole
dc.contributor.authorSheppard, Anna E.
dc.contributor.authorPeirano, Gisele
dc.contributor.authorSebra, Robert
dc.contributor.authorLynch, Tarah
dc.contributor.authorAnson, Luke
dc.contributor.authorKasarskis, Andrew
dc.contributor.authorMotyl, Mary R.
dc.contributor.authorCrook, Derrick W.
dc.contributor.authorPitout, Johann D.D.
dc.date.accessioned2016-06-24T08:03:13Z
dc.date.available2016-06-24T08:03:13Z
dc.date.issued2016-08
dc.description.abstractThe blaIMP-14 carbapenem resistance gene has largely previously been observed in Pseudomonas aeruginosa and Acinetobacter spp. As part of global surveillance and sequencing of carbapenem-resistant E. coli, we identified an ST131 strain harboring blaIMP-14 within a class 1 integron, itself nested within a ~54kb multi-drug resistance region on an epidemic IncA/C2 plasmid. The emergence of blaIMP-14 in this context in the ST131 lineage is of potential clinical concern.en_ZA
dc.description.departmentMedical Microbiologyen_ZA
dc.description.librarianhb2016en_ZA
dc.description.urihttp://aac.asm.orgen_ZA
dc.identifier.citationStoesser, N, Sheppard, AE, Peirano, G, Sebra, R, Lynch, T, Anson, L, Kasarskis, A, Motyl, MR, Crook, DW & Pitout, JDD 2016, 'First report of blaIMP-14 on a plasmid harboring multiple drug resistance genes in Escherichia coli sequence type 131', Antimicrobial Agents and Chemotherapy, vol. 60, no. 8, pp. 5068-5071.en_ZA
dc.identifier.issn0066-4804 (print)
dc.identifier.issn1098-6596 (online)
dc.identifier.other10.1128/AAC.00840-16
dc.identifier.urihttp://hdl.handle.net/2263/53392
dc.language.isoenen_ZA
dc.publisherAmerican Society for Microbiologyen_ZA
dc.rights© 2016 Stoesser et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.en_ZA
dc.subjectPseudomonas aeruginosaen_ZA
dc.subjectAcinetobacter spp.en_ZA
dc.subjectGlobal surveillanceen_ZA
dc.titleFirst report of blaIMP-14 on a plasmid harboring multiple drug resistance genes in Escherichia coli sequence type 131en_ZA
dc.typeArticleen_ZA

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