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Browsing Research Articles (Veterinary Tropical Diseases) by Author "Faber, Erika"

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Apoptosis versus survival of African horse sickness virus serotype 4-infected horse peripheral blood mononuclear cells

Faber, Erika; Tshilwane, Selaelo Ivy; Van Kleef, Mirinda; Pretorius, Alri (Elsevier, 2022-01)

Expanding on our previous work, this study used transcriptome analysis of RNA sequences to investigate the various factors that contributed to either inducing apoptosis that resulted in cell death or promoting the survival ...
Identification of T cell and linear B cell epitopes on African horse sickness virus serotype 4 proteins VP1-1, VP2, VP4, VP7 and NS3

Faber, Erika; Van Schalkwyk, Antoinette; Tshilwane, Selaelo Ivy; Van Kleef, Mirinda; Pretorius, Alri (Elsevier, 2024-01)

The viral proteins VP1-1, VP2, VP4, VP7 and NS3, of African horse sickness virus serotype 4 (AHSV4), have previously been identified to contain CD8+ T cell epitopes. In this study, overlapping peptides spanning the entire ...
The impact of Escherichia coli contamination products present in recombinant African horse sickness virus serotype 4 proteins on the innate and humoral immune responses

Faber, Erika; Tshilwane, Selaelo Ivy; Van Kleef, Mirinda; Pretorius, Alri (Elsevier, 2022-12)

Transcriptome analysis was used to characterise the in vitro primary and secondary immune responses induced in horse peripheral blood mononuclear cells (PBMC) stimulated for 24 h with the individual recombinant proteins ...
In vitro propagation and genome sequencing of three ‘atypical’ Ehrlichia ruminantium isolates

Liebenberg, Junita; Steyn, Helena C.; Josemans, Antoinette I.; Faber, Erika; Zweygarth, Erich (AOSIS OpenJournals, 2020-06-24)

Three isolates of Ehrlichia ruminantium (Kümm 2, Omatjenne and Riverside), the causative agent of heartwater in domestic ruminants, were isolated in Ixodes scapularis (IDE8) tick cell cultures using the leukocyte fraction ...
Virulent African horse sickness virus serotype 4 interferes with the innate immune response in horse peripheral blood mononuclear cells in vitro

Faber, Erika; Tshilwane, Selaelo Ivy; Van Kleef, Mirinda; Pretorius, Alri (Elsevier, 2021-07)

African horse sickness (AHS) is caused by African horse sickness virus (AHSV), a double stranded RNA (dsRNA) virus of the genus Orbivirus, family Reoviridae. For the development of new generation AHS vaccines or antiviral ...

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Browsing Research Articles (Veterinary Tropical Diseases) by Author "Faber, Erika"

Browsing Research Articles (Veterinary Tropical Diseases) by Author "Faber, Erika"

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