Browsing Research Articles (Medical Microbiology) by UP Author "Fourie, P.B. (Petrus Bernardus)"
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Browsing Research Articles (Medical Microbiology) by UP Author "Fourie, P.B. (Petrus Bernardus)"
Now showing items 1-20 of 22
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Osei Sekyere, John; Reta, Melese Abate; Maningi, Nontuthuko Excellent; Fourie, P.B. (Petrus Bernardus) (Elsevier, 2019-12)BACKGROUND : Tuberculosis (TB) remains a main global public health problem. However, a systematic review of TB resistance epidemiology in Africa is wanting. METHODS : A comprehensive systematic search of PubMed, Web of ...
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Deretic, Vojo; Prossnitz, Eric; Burge, Mark; Campen, Matthew J.; Cannon, Judy; Liu, Ke Jian; Sklar, Larry A.; Allers, Lee; Garcia, Sally Ann; Baehrecke, Eric H.; Behrends, Christian; Cecconi, Francesco; Codogno, Patrice; Chen, Guang-Chao; Elazar, Zvulun; Eskelinen, Eeva-Liisa; Fourie, P.B. (Petrus Bernardus); Gozuacik, Devrim; Hong, Wanjin; Hotamisligi, Gokhan; Jaattela, Marja; Jo, Eun-Kyeong; Johansen, Terje; Juhasz, Gábor; Kimchi, Adi; Ktistakis, Nicholas; Kroemer, Guido; MIzushima, Noboru; Munz, Christian; Reggiori, Fulvio; Rubinsztein, David; Ryan, Kevin; Schroder, Kate; Simonsen, Anne; Tooze, Sharon; Vaccaro, Maria I.; Yoshimori, Tamotsu; Yu, Li; Zhang, Hong; Klionsky, Daniel J. (Taylor and Francis, 2018)Recently, NIH has funded a center for autophagy research named the Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence, located at the University of New Mexico Health Science Center (UNM ...
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Mahomed, Hassan; Fourie, P.B. (Petrus Bernardus) (Elsevier, 2012)A new efficacious tuberculosis (TB) vaccine has the potential to dramatically assist control efforts for the global TB epidemic. Good progress has been made with the clinical development of new TB vaccine candidates with ...
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Hickey, Anthony J.; Misra, Amit; Fourie, P.B. (Petrus Bernardus) (Wiley-Blackwell, 2013-11)Inhaled therapies offer a unique approach to the treatment of tuberculosis (TB) using a relevant target organ system as a route of administration. The number of research reports on this topic has been increasing exponentially ...
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Omar, Shaheed Vally; Peters, Remco P.H.; Ismail, Nazir Ahmed; Jonkman, Kelly; Dreyer, Andries W.; Said, Halima M.; Gwalab, Thabisile; Ismail, Nabila; Fourie, P.B. (Petrus Bernardus) (Wiley, 2016-06)Molecular tests are revolutionizing diagnosis of tuberculosis (TB). Disease burden is concentrated in resource-poor countries with inadequate infrastructure and capacity resulting in delays for specimens to reach the ...
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Maningi, Nontuthuko Excellent; Daum, Luke T.; Rodriguez, John D.; Mphahlele, Matsie; Peters, Remco P.H.; Fischer, Gerald W.; Chambers, James P.; Fourie, P.B. (Petrus Bernardus) (American Society for Microbiology, 2015-12)Technical limitations of common tests used for detecting pyrazinamide (PZA) resistance in Mycobacterium tuberculosis (MTB) isolates pose challenges for comprehensive and accurate descriptions of drug resistance in patients ...
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Omar, Shaheed Vally; Peters, Remco P.H.; Ismail, Nazir Ahmed; Dreyer, Andries W.; Said, Mohamed; Gwala, Thabisile; Ismail, Nabila; Fourie, P.B. (Petrus Bernardus) (Elsevier, 2015-10)BACKGROUND : Modern molecular-based approaches for the detection of Mycobacterium tuberculosis in sputum samples promise quicker and more accurate detection of cases. However, processing sputum samples at central diagnostic ...
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Cholo, Moloko C.; Mothiba, Maborwa T.; Fourie, P.B. (Petrus Bernardus); Anderson, Ronald (Oxford University Press, 2017-02)Drug-resistant (DR)-tuberculosis (TB) is the major challenge confronting the global tuberculosis (TB) control programme, necessitating treatment with second-line anti- TB drugs, often with limited therapeutic efficacy. ...
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Daum, Luke T.; Peters, Remco P.H.; Fourie, P.B. (Petrus Bernardus); Jonkman, K.; Worthy, Sue A.; Rodriguez, John D.; Ismail, Nazir Ahmed; Omar, Shaheed Vally; Fischer, Gerald W. (International Union Against Tuberculosis and Lung Disease, 2015-05)SETTING : Mopani District, South Africa. OBJECTIVE : To explore remote, molecular detection of Mycobacterium tuberculosis from sputum transported using PrimeStorew Molecular Transport Medium (PSMTM) compared to settings ...
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Maningi, Nontuthuko Excellent; Daum, Luke T.; Rodriguez, John D.; Said, Halima M.; Peters, Remco P.H.; Osei Sekyere, John; Fischer, Gerald W.; Chambers, James P.; Fourie, P.B. (Petrus Bernardus) (American Society for Microbiology, 2018-05)Modern advances in genomics provide an opportunity to reinterpret historical bacterial culture collections. In this study, genotypic antibiotic resistance profiles of Mycobacterium tuberculosis isolates from a historical ...
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Reta, Melese Abate; Tamene, Birhan Alemnew; Abate, Biruk Beletew; Mensah, Eric; Maningi, Nontuthuko Excellent; Fourie, P.B. (Petrus Bernardus) (MDPI, 2022-10-14)BACKGROUND : Tuberculosis (TB) remains a significant global public health issue, despite advances in diagnostic technologies, substantial global efforts, and the availability of effective chemotherapies. Mycobacterium ...
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Osei Sekyere, John; Maningi, Nontuthuko Excellent; Fourie, P.B. (Petrus Bernardus) (Wiley, 2020-05)Increasingly, gut microbiota distortions are being implicated in the pathogenesis of several infectious and noninfectious diseases. Specifically, in the absence of an eubiotic microbiota, mice are more prone to colonization ...
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Daum, Luke T.; Rodriguez, John D.; Worthy, Sue A.; Ismail, Nazir Ahmed; Omar, Shaheed Vally; Dreyer, Andries W.; Fourie, P.B. (Petrus Bernardus); Hoosen, Anwar Ahmed; Chambers, James P.; Fischer, Gerald W. (American Society for Microbiology, 2012-12)A novel protocol for full-length Mycobacterium tuberculosis gene analysis of first- and second-line drug resistance was developed using the Ion Torrent Personal Genome Machine (PGM). Five genes—rpoB (rifampin), katG ...
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Daum, Luke T.; Fourie, P.B. (Petrus Bernardus); Bhattacharyya, Sanjib; Ismail, Nazir Ahmed; Gradus, Steve; Maningi, N.E. (Nontuthuko Excellent); Omar, Shaheed Vally; Fischer, Gerald W. (Oxford University Press, 2014-03-15)No abstract available.
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Sei, Clara J.; Shey, Bong-Akee; Schuman, Richard F.; Rikhi, Nimisha; Muema, Kevin; Rodriguez, John D.; Daum, Luke T.; Fourie, P.B. (Petrus Bernardus); Fischer, Gerald W. (Elsevier, 2019-09)BACKGROUND : Patients with impaired immunity often have rapid progression of tuberculosis (TB) which can lead to highly lethal Mycobacterium tuberculosis (MTB) sepsis. Opsonic monoclonal antibodies (MABs) directed ...
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Dhillon, Jasvir; Fourie, P.B. (Petrus Bernardus); Mitchison, D.A. (Oxford University Press, 2014-02)OBJECTIVES : Can the characteristics of persisters in cultures of Mycobacterium tuberculosis also be found in bacilli from the sputum of pulmonary tuberculosis patients? The objective of this study was to explore whether ...
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Dharmadhikari, Ashwin S.; Kabadi, Mohan; Gerety, Bob; Hickey, Anthony J.; Fourie, P.B. (Petrus Bernardus); Nardell, Edward Anthony (American Society for Microbiology, 2013-06)Multidrug-resistant tuberculosis (MDR-TB) threatens global TB control. The lengthy treatment includes one of the injectable drugs kanamycin, amikacin, and capreomycin, usually for the first 6 months. These drugs have ...
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Hennig, Stefanie; Svensson, Elin M.; Niebecker, Ronald; Fourie, P.B. (Petrus Bernardus); Weiner, Marc H.; Bonora, Stefano; Peloquin, Charles A.; Gallicano, Keith; Flexner, Charles; Pym, Alex; Vis, Peter; Olliaro, Piero L.; McIlleron, Helen; Karlsson, Mats O. (Oxford University Press, 2016-05)OBJECTIVES : Extensive but fragmented data from existing studies were used to describe the drug-drug interaction between rifabutin and HIV-protease inhibitors, and predict doses achieving recommended therapeutic exposure ...
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Reta, Melese Abate; Alemnew, Birhan; Abate, Biruk Beletew; Fourie, P.B. (Petrus Bernardus) (Elsevier, 2021-09)OBJECTIVES : Globally, the incidence and mortality of tuberculosis (TB) are declining; however, low detection of drug-resistant disease threatens to reverse current progress toward global TB control. Multiple rapid molecular ...
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Osei Sekyere, John; Reta, Melese Abate; Fourie, P.B. (Petrus Bernardus) (Wiley, 2021-10)Please read abstract in the article.
Now showing items 1-20 of 22