Browsing Research Articles (Biochemistry) by Title

Browsing Research Articles (Biochemistry) by Title

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  • H3ABioNet, a sustainable pan-African bioinformatics network for human heredity and health in Africa 
    Mulder, Nicola J.; Adebiyi, Ezekiel; Alami, Raouf; Benkahla, Alia; Brandful, James; Doumbia, Seydou; Everett, Dean; Fadlelmola, Faisal M.; Gaboun, Fatima; Gaseitsiwe, Simani; Ghazal, Hassan; Hazelhurst, Scott; Hide, Winston; Ibrahimi, Azeddine; Fakim, Yasmina Jaufeerally; Jongeneel, C. Victor; Joubert, Fourie; Kassim, Samar; Kayondo, Jonathan; Kumuthini, Judit; Lyantagaye, Sylvester; Makani, Julie; Alzohairy, Ahmed Mansour; Masiga, Daniel; Moussa, Ahmed; Nash, Oyekanmi; Oukem-Boyer, Odile Ouwe Missi; Owusu-Dabo, Ellis; Panji, Sumir; Patterton, Hugh; Radouani, Fouzia; Sadki, Khalid; Seghrouchni, Fouad; Bishop, Ozlem Tastan; Tiffin, Nicki; Ulenga, Nzovu; The H3ABioNet Consortium (Cold Spring Harbor Laboratory Press, 2016-12-01)
    The application of genomics technologies to medicine and biomedical research is increasing in popularity, made possible by new high-throughput genotyping and sequencing technologies and improved data analysis capabilities. ...
  • H3K36 methylation reprograms gene expression to drive early gametocyte development in Plasmodium falciparum 
    Connacher, Jessica I.; Josling, Gabrielle A.; Orchard, Lindsey M.; Reader, Janette; Llinas, Manuel; Birkholtz, Lyn-Marie (BMC, 2021-04)
    BACKGROUND : The Plasmodium sexual gametocyte stages are the only transmissible form of the malaria parasite and are thus responsible for the continued transmission of the disease. Gametocytes undergo extensive functional ...
  • Hardwood tree genomics : unlocking woody plant biology 
    Tuskan, Gerald A.; Groover, Andrew T.; Schmutz, Jeremy; DiFazio, Stephen Paul; Myburg, Alexander Andrew; Grattapaglia, Dario; Smart, Lawrence B.; Yin, Tongming; Aury, Jean-Marc; Kremer, Antoine; Leroy, Thibault; Le Provost, Gregoire; Plomion, Christophe; Carlson, John E.; Randall, Jennifer; Westbrook, Jared; Grimwood, Jane; Muchero, Wellington; Jacobson, Daniel; Michener, Joshua K. (Frontiers Media, 2018-12-17)
    Woody perennial angiosperms (i.e., hardwood trees) are polyphyletic in origin and occur in most angiosperm orders. Despite their independent origins, hardwoods have shared physiological, anatomical, and life history ...
  • Harmonising the fields of invasion science and forest pathology 
    Paap, Trudy; Wingfield, Michael J.; Burgess, Treena I.; Hulbert, J.M. (Joey); Santini, Alberto (Pensoft Publishers, 2020-10-15)
    Invasive alien species are widely recognised as significant drivers of global environmental change, with far reaching ecological and socio-economic impacts. The trend of continuous increases in first records, with no ...
  • Harnessing the potential of precision pest management in plantation forests 
    Slippers, Bernard; Hurley, Brett Phillip; Allison, Jeremy D. (NISC (Pty) Ltd and Informa UK Limited (trading as Taylor and Francis Group), 2020)
    There are numerous new and emerging technologies that allow for greater precision in forest pest management, from sequencing and chemical analyses to data collection through smart technologies, and integration, analysis ...
  • Headspace volatiles of the edible fruit pulp of Parinari curatellifolia growing in Malawi using solid phase microextraction 
    Shoko, Tinotenda; Saka, J.D. Kalenga; Apostolides, Zeno (Elsevier, 2014-01)
    Head-space volatiles of the edible pulp of the mobola plum (Parinari curatellifolia) were extracted using solid phase microextraction (SPME), and their identities determined by GC–FID and GC–MS systems. The SPME method ...
  • The healthy human blood microbiome : fact or fiction? 
    Castillo, Diego J.; Rifkin, Riaan F.; Cowan, Don A.; Potgieter, Marnie (Frontiers Media, 2019-05-08)
    The blood that flows perpetually through our veins and arteries performs numerous functions essential to our survival. Besides distributing oxygen, this vast circulatory system facilitates nutrient transport, deters ...
  • Heterologous expression or plasmodial proteins for structural studies and functional annotation 
    Birkholtz, Lyn-Marie; Blatch, Gregory; Coetzer, Theresa L.; Hoppe, Heinrich C.; Human, Esmare; Morris, Elizabeth J.; Ngcete, Zoleka; Oldfield, Lyndon; Roth, Robyn; Shonhai, Addmore; Stephens, Linda L.; Louw, Abraham Izak (BioMed Central, 2008)
    Malaria remains the world's most devastating tropical infectious disease with as many as 40% of the world population living in risk areas. The widespread resistance of Plasmodium parasites to the cost-effective chloroquine ...
  • Hierarchical transcriptional control regulates Plasmodium falciparum sexual differentiation 
    Van Biljon, Riette Andele; Van Wyk, Roelof Daniel Jacobus; Painter, Heather J.; Orchard, Lindsey; Reader, Janette; Niemand, Jandeli; Llinas, Manuel; Birkholtz, Lyn-Marie (BioMed Central, 2019-12)
    BACKGROUND : Malaria pathogenesis relies on sexual gametocyte forms of the malaria parasite to be transmitted between the infected human and the mosquito host but the molecular mechanisms controlling gametocytogenesis ...
  • High diversity of Diaporthe species associated with pear shoot canker in China 
    Guo, Y.S.; Crous, Pedro W.; Bai, Q.; Fu, M.; Yang, M.M.; Wang, X.H.; Du, Y.M.; Hong, N.; Xu, W.X.; Wang, G.P. (Naturalis Biodiversity Center and Centraalbureau voor Schimmelcultures, 2020-02-06)
    Species of Diaporthe (syn. Phomopsis) are important endophytes, saprobes and pathogens, infecting a wide range of plants and resulting in important crop diseases. However, the species occurring on pear remain largely unresolved. ...
  • High genetic diversity of Fusarium circinatum associated with the first outbreak of pitch canker on Pinus patula in South Africa 
    Fru, Felix Fon; Steenkamp, Emma Theodora; Wingfield, Michael J.; Roux, Jolanda (NISC (Pty) Ltd and Informa UK Limited (trading as Taylor & Francis Group), 2019)
    The disease known as pitch canker results from infection of Pinus species by the fungus Fusarium circinatum. This fungus also causes a serious root disease of Pinus seedlings and cuttings in forestry nurseries. Pinus radiata ...
  • High levels of imported asymptomatic malaria but limited local transmission in KwaZulu‑Natal, a South African malaria‑endemic province nearing malaria elimination 
    Raman, Jaishree; Gast, Laura; Balawanth, Ryleen; Tessema, Sofonias; Brooke, Basil; Maharaj, Rajendra; Munhenga, Givemore; Tshikae, Power; Lakan, Vishan; Mwamba, Tshiama; Makowa, Hazel; Sangweni, Lindi; Mkhabela, Moses; Zondo, Nompumelelo; Mohulatsi, Ernest; Nyawo, Zuziwe; Ngxongo, Sifiso; Msimang, Sipho; Dagata, Nicole; Greenhouse, Bryan; Birkholtz, Lyn-Marie; Shirreff, George; Graffy, Rebecca; Qwabe, Bheki; Moonasar, Devanand (BioMed Central, 2020-04-15)
    BACKGROUND : KwaZulu-Natal, one of South Africa’s three malaria endemic provinces, is nearing malaria elimination, reporting fewer than 100 locally-acquired cases annually since 2010. Despite sustained implementation of ...
  • A high-quality fungal genome assembly resolved from a sample accidentally contaminated by multiple taxa 
    Aylward, Janneke; Wingfield, Michael J.; Roets, Francois; Wingfield, Brenda D. (Future Science Ltd, 2022-02)
    Contamination in sequenced genomes is a relatively common problem and several methods to remove non-target sequences have been devised. Typically, the target and contaminating organisms reside in different kingdoms, ...
  • Highly transferable microsatellite markers for the genera Lasiodiplodia and Neofusicoccum 
    Nagel, Jan Hendrik; Cruywagen, Elsie M.; Machua, Joseph; Wingfield, Michael J.; Slippers, Bernard (Elsevier, 2020-04)
    Population genetic studies play an integral role in understanding the ecology and management of fungal plant pathogens. Such studies for species of Botryosphaeriaceae are hampered by a lack of available markers. Genomic ...
  • The history and distribution of nodulating Paraburkholderia, a potential inoculum for Fynbos forage species 
    Beukes, Chrizelle Winsie; Venter, S.N. (Stephanus Nicolaas); Steenkamp, Emma Theodora (Wiley, 2021-03)
    Legumes in the Fynbos vegetation of the Western Cape of South Africa have emerged as candidates for domestication, particularly for their adaptation to acidic and infertile soils. However, South African rhizobia have ...
  • HIV therapeutic possibilities of gold compounds 
    Fonteh, Pascaline Nanga; Keter, Frankline K.; Meyer, Debra (Springer, 2010-02)
    Highly active antiretroviral therapy (HAART) has resulted in decreased mortality and morbidity from the acquired immune deficiency syndrome caused by the human immunodeficiency virus (HIV). Drug resistance and toxicity ...
  • Holoprosencephaly with clefts : data of 85 patients, treatment and outcome : Part 1 : History, subdivisions, and data on 85 holoprosencephalic cleft patients 
    Honey, Engela M.; Butow, Kurt-Wilhelm; Zwahlen, Roger Arthur (Medknow Publications, 2019-01)
    Cleft patients with Holoprosencephaly (HPE) constitute a controversy due to a variable facial appearance. HPE appearance varies from only a columella to a prolabium‑premaxilla complex agenesis up to a common unilateral ...
  • Horizontally acquired quorum-sensing regulators recruited by the PhoP regulatory network expand the host adaptation repertoire in the phytopathogen Pectobacterium brasiliense 
    Bellieny-Rabelo, Daniel; Nkomo, Ntombikayise Precious; Shyntum, Divine Yufetar; Moleleki, Lucy N. (American Society for Microbiology, 2020-01-28)
    In this study, we examine the impact of transcriptional network rearrangements driven by horizontal gene acquisition in PhoP and SlyA regulons using as a case study a phytopathosystem comprised of potato tubers and the ...
  • Host specificity tests reveals new host of a global biological control agent Psyllaephagus bliteus (Hymenoptera: Encyrtidae) 
    Bush, Samantha J.; Slippers, Bernard; Dittrich-Schroder, Gudrun; Hurley, Brett Phillip (Entomological Society of Southern Africa, 2020-09)
    Glycaspis brimblecombei (Hemiptera: Aphalaridae) is an invasive, sap-sucking eucalypt pest in various parts of the world. Psyllaephagus bliteus(Hymenoptera: Encyrtidae) was first released as a biological control agent ...
  • How methylglyoxal kills bacteria : an ultrastructural study 
    Rabie, E.; Serem, June Cheptoo; Oberholzer, Hester Magdalena; Gaspar, Anabella Regina Marques; Bester, Megan Jean (Taylor and Francis, 2016-03)
    Antibacterial activity of honey is due to the presence of methylglyoxal (MGO), H2O2, bee defensin as well as polyphenols. High MGO levels in manuka honey are the main source of antibacterial activity. Manuka honey has ...