Tryptophan end-tagging confers antifungal activity on a tick-derived peptide by triggering reactive oxygen species production
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Date
Authors
Chiramba, Court Kudakwashe
Moller, Dalton Sharl
Lorenz, Christian D.
Chirombo, Rumbidzai Ruth
Mason, A. James
Bester, Megan Jean
Gaspar, Anabella Regina Marques
Journal Title
Journal ISSN
Volume Title
Publisher
American Chemical Society
Abstract
Please read abstract in the article.
Description
DATA AVAILABILITY STATEMENT : All data supporting the findings of this study are available in
the figures and Supporting Information.
SUPPLEMENTARY MATERIAL : Effect of antifungal agents on cell growth and viability; biofilm preventing activity of AMB, Os−C, and Os− C(W5); biofilm eradicating activity of AMB and Os− C(W5); microscopy images of cells exposed to AMB; and HPLC and MS data for Os−C and Os−C(W5).
SUPPLEMENTARY MATERIAL : Effect of antifungal agents on cell growth and viability; biofilm preventing activity of AMB, Os−C, and Os− C(W5); biofilm eradicating activity of AMB and Os− C(W5); microscopy images of cells exposed to AMB; and HPLC and MS data for Os−C and Os−C(W5).
Keywords
Biofilms, Membranes, Monomers, Peptides and proteins, Vesicles, Antimicrobial peptide (AMP), Tryptophan end-tagging, Antifungal activity, Physiological salt environments, SDG-03: Good health and well-being
Sustainable Development Goals
SDG-03:Good heatlh and well-being
Citation
Chiramba, C.K., Möller, D.S., Lorenz, C.D. et al. 2024, 'Tryptophan end-tagging confers antifungal activity on a tick-derived peptide by triggering reactive oxygen species production', ACS Omega, vol. 9, no. 13, pp. 15556–15572, doi : 10.1021/acsomega.4c00478.