In-silico reverse docking and in-vitro studies identified curcumin, 18α-glycyrrhetinic acid, rosmarinic acid, and quercetin as inhibitors of α-glucosidase and pancreatic α-amylase and lipid accumulation in HepG2 cells, important type 2 diabetes targets

dc.contributor.authorTshiyoyo, Kadima Samuel
dc.contributor.authorBester, Megan Jean
dc.contributor.authorSerem, June Cheptoo
dc.contributor.authorApostolides, Zeno
dc.date.accessioned2023-02-17T06:50:16Z
dc.date.issued2022-10
dc.description.abstractPlease read abstract in the article.en_US
dc.description.departmentAnatomyen_US
dc.description.departmentBiochemistryen_US
dc.description.departmentGeneticsen_US
dc.description.departmentMicrobiology and Plant Pathologyen_US
dc.description.embargo2023-06-22
dc.description.librarianhj2023en_US
dc.description.librarianem2025en
dc.description.sdgSDG-03: Good health and well-beingen
dc.description.sponsorshipThe National Research Foundation (NRF) of South Africa.en_US
dc.description.urihttp://www.elsevier.com/locate/molstren_US
dc.identifier.citationTshiyoyo, K.S., Bester, M.J., Serem, J.C. et al. 2022, 'In-silico reverse docking and in-vitro studies identified curcumin, 18α-glycyrrhetinic acid, rosmarinic acid, and quercetin as inhibitors of α-glucosidase and pancreatic α-amylase and lipid accumulation in HepG2 cells, important type 2 diabetes targets', Journal of Molecular Structure, vol. 1266, art. 133492, pp. 1-10, doi : 10.1016/j.molstruc.2022.133492.en_US
dc.identifier.issn0022-2860 (print)
dc.identifier.issn1872-8014 (online)
dc.identifier.other10.1016/j.molstruc.2022.133492
dc.identifier.urihttps://repository.up.ac.za/handle/2263/89650
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.rights© 2022 Elsevier B.V. All rights reserved. Notice : this is the author’s version of a work that was accepted for publication in Journal of Molecular Structure. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. A definitive version was subsequently published in Journal of Molecular Structure, vol. 1266, art. 133492, pp. 1-10, doi : 10.1016/j.molstruc.2022.133492.en_US
dc.subjectα-amylaseen_US
dc.subjectα-glucosidaseen_US
dc.subjectHerbal compoundsen_US
dc.subjectHepatic lipid accumulationen_US
dc.subjectIn-vitro cytotoxicityen_US
dc.subjectReverse molecular dockingen_US
dc.subjectType 2 diabetes mellitus (T2DM)en_US
dc.subject.otherHealth sciences articles SDG-03
dc.subject.otherSDG-03: Good health and well-being
dc.titleIn-silico reverse docking and in-vitro studies identified curcumin, 18α-glycyrrhetinic acid, rosmarinic acid, and quercetin as inhibitors of α-glucosidase and pancreatic α-amylase and lipid accumulation in HepG2 cells, important type 2 diabetes targetsen_US
dc.typePostprint Articleen_US

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