In silico and in vitro evaluation of flavonoid derivatives for diabetes management : molecular dynamics, and enzyme kinetics for pancreatic alpha-amylase and alpha-glucosidase

dc.contributor.authorMcMillan, Jamie
dc.contributor.authorBester, Megan Jean
dc.contributor.authorApostolides, Zeno
dc.contributor.emailu16016760@tuks.co.za
dc.date.accessioned2026-02-25T10:38:03Z
dc.date.issued2025-11
dc.descriptionDATA AVAILABILITY : Datasets from the current study are available from the corresponding author upon request.
dc.description.abstractPlease read abstract in the article.
dc.description.departmentBiochemistry, Genetics and Microbiology (BGM)
dc.description.departmentAnatomy
dc.description.embargo2026-11-21
dc.description.librarianhj2026
dc.description.sdgSDG-03: Good health and well-being
dc.description.sponsorshipThe Paul Junior Chukwuzulum Ajemba grant.
dc.description.urihttps://link.springer.com/journal/40203
dc.identifier.citationMcMillan, J., Bester, M.J. & Apostolides, Z. In silico and in vitro evaluation of flavonoid derivatives for diabetes management: molecular dynamics, and enzyme kinetics for pancreatic alpha-amylase and alpha-glucosidase. In Silico Pharmacology 13, 187 (2025). https://doi.org/10.1007/s40203-025-00493-4 .
dc.identifier.issn2193-9616 (online)
dc.identifier.other10.1007/s40203-025-00493-4
dc.identifier.urihttp://hdl.handle.net/2263/108638
dc.language.isoen
dc.publisherSpringer
dc.rights© The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2025. The original publication is available at : https://link.springer.com/journal/40203.
dc.subjectMolecular docking
dc.subjectMolecular dynamics
dc.subjectMMGBSA
dc.subjectAmylase
dc.subjectGlucosidase
dc.subjectFlavonoids
dc.titleIn silico and in vitro evaluation of flavonoid derivatives for diabetes management : molecular dynamics, and enzyme kinetics for pancreatic alpha-amylase and alpha-glucosidase
dc.typePostprint Article

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