In silico and in vitro evaluation of flavonoid derivatives for diabetes management : molecular dynamics, and enzyme kinetics for pancreatic alpha-amylase and alpha-glucosidase

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Date

2025-11

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Publisher

Springer

Abstract

Please read abstract in the article.

Description

DATA AVAILABILITY : Datasets from the current study are available from the corresponding author upon request.

Keywords

Molecular docking, Molecular dynamics, MMGBSA, Amylase, Glucosidase, Flavonoids

Sustainable Development Goals

SDG-03: Good health and well-being

Citation

McMillan, J., Bester, M.J. & Apostolides, Z. In silico and in vitro evaluation of flavonoid derivatives for diabetes management: molecular dynamics, and enzyme kinetics for pancreatic alpha-amylase and alpha-glucosidase. In Silico Pharmacology 13, 187 (2025). https://doi.org/10.1007/s40203-025-00493-4 .

URI

http://hdl.handle.net/2263/108638

Collections

Research Articles (Biochemistry, Genetics and Microbiology (BGM))
Research Articles (Anatomy)
Research Articles (University of Pretoria)
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