dc.contributor.author |
Reier-Nilsen, Tonje
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|
dc.contributor.author |
Sewry, Nicola
|
|
dc.contributor.author |
Chenuel, Bruno
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|
dc.contributor.author |
Backer, Vibeke
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|
dc.contributor.author |
Larsson, Kjell
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|
dc.contributor.author |
Price, Oliver J.
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|
dc.contributor.author |
Pedersen, Lars
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|
dc.contributor.author |
Bougault, Valerie
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|
dc.contributor.author |
Schwellnus, Martin Peter
|
|
dc.contributor.author |
Hull, James H.
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|
dc.date.accessioned |
2023-03-14T08:50:59Z |
|
dc.date.available |
2023-03-14T08:50:59Z |
|
dc.date.issued |
2023-04 |
|
dc.description.abstract |
OBJECTIVES : To compare the performance of various diagnostic bronchoprovocation tests (BPT) in the assessment of lower airway dysfunction (LAD) in athletes and inform best clinical practice.
DESIGN : Systematic review with sensitivity and specificity meta-analyses.
DATA SOURCES : PubMed, EBSCOhost and Web of Science (1 January 1990–31 December 2021).
ELIGIBILITY CRITERIA : Original full-text studies, including athletes/physically active individuals (15–65 years) who underwent assessment for LAD by symptom-based questionnaires/history and/or direct and/or indirect BPTs.
RESULTS : In 26 studies containing data for quantitative meta-analyses on BPT diagnostic performance (n=2624 participants; 33% female); 22% had physician diagnosed asthma and 51% reported LAD symptoms. In athletes with symptoms of LAD, eucapnic voluntary hyperpnoea (EVH) and exercise challenge tests (ECTs) confirmed the diagnosis with a 46% sensitivity and 74% specificity, and 51% sensitivity and 84% specificity, respectively, while methacholine BPTs were 55% sensitive and 56% specific. If EVH was the reference standard, the presence of LAD symptoms was 78% sensitive and 45% specific for a positive EVH, while ECTs were 42% sensitive and 82% specific. If ECTs were the reference standard, the presence of LAD symptoms was 80% sensitive and 56% specific for a positive ECT, while EVH demonstrated 65% sensitivity and 65% specificity for a positive ECT.
CONCLUSION : In the assessment of LAD in athletes, EVH and field-based ECTs offer similar and moderate diagnostic test performance. In contrast, methacholine BPTs have lower overall test performance. |
en_US |
dc.description.department |
Sports Medicine |
en_US |
dc.description.librarian |
hj2023 |
en_US |
dc.description.uri |
http://bjsm.bmj.com |
en_US |
dc.identifier.citation |
Reier-Nilsen, T., Sewry, N., Chenuel, B. et al. Diagnostic approach to lower airway dysfunction in athletes: a systematic review and meta-analysis by a subgroup of the IOC consensus on ‘acute respiratory illness in the athlete’. British Journal of Sports Medicine 2023 Apr;57(8):481-489. doi: 10.1136/bjsports-2022-106059. |
en_US |
dc.identifier.issn |
0306-3674 (print) |
|
dc.identifier.issn |
1473-0480 (online) |
|
dc.identifier.other |
10.1136/bjsports-2022-106059 |
|
dc.identifier.uri |
https://repository.up.ac.za/handle/2263/90103 |
|
dc.language.iso |
en |
en_US |
dc.publisher |
BMJ Publishing Group |
en_US |
dc.rights |
© Author(s) (or their employer(s)) 2023. |
en_US |
dc.subject |
Asthma |
en_US |
dc.subject |
Athletes |
en_US |
dc.subject |
Exercise‐induced bronchoconstriction |
en_US |
dc.subject |
Diagnosis |
en_US |
dc.subject |
Respiratory symptoms |
en_US |
dc.subject |
Bronchoprovocation tests (BPT) |
en_US |
dc.subject |
Lower airway dysfunction (LAD) |
en_US |
dc.title |
Diagnostic approach to lower airway dysfunction in athletes: a systematic review and meta-analysis by a subgroup of the IOC consensus on acute respiratory illness in the athlete' |
en_US |
dc.type |
Postprint Article |
en_US |