Chemogenomic fingerprints associated with stage-specific gametocytocidal compound action against human malaria parasites

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Authors

Niemand, Jandeli
Van Biljon, Riette Andele
Van der Watt, Mariette Elizabeth
Van Heerden, Ashleigh
Reader, Janette
Van Wyk, Roelof Daniel Jacobus
Orchard, Lindsey M.
Chibale, Kelly
Llinas, Manuel
Birkholtz, Lyn-Marie

Journal Title

Journal ISSN

Volume Title

Publisher

American Chemical Society

Abstract

Please read abstract in the article.

Description

Supplementary material 1: Figure S1: MMV390048 or MMV642943 chemical structures. Figure S2: Verification of microarray-identified differential gene expression with qPCR analyses (PDF)
Supplementary material 2: Additional Excel File provided with a summary of the full gene expression data set with GO and cluster analyses (XLSX)

Keywords

Gametocyte, Drug response, Kinase, Stage-specific, Chemogenomic, Plasmodium

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Citation

Niemand, J., Van Biljon, R., Van Der Watt, M. et al. 2021, 'Chemogenomic fingerprints associated with stage-specific gametocytocidal compound action against human malaria parasites', ACS Infectious Diseases, vol. 7. no. 10, pp. 2904-2916.