Chemogenomic fingerprints associated with stage-specific gametocytocidal compound action against human malaria parasites

dc.contributor.authorNiemand, Jandeli
dc.contributor.authorVan Biljon, Riette Andele
dc.contributor.authorVan der Watt, Mariette Elizabeth
dc.contributor.authorVan Heerden, Ashleigh
dc.contributor.authorReader, Janette
dc.contributor.authorVan Wyk, Roelof Daniel Jacobus
dc.contributor.authorOrchard, Lindsey M.
dc.contributor.authorChibale, Kelly
dc.contributor.authorLlinas, Manuel
dc.contributor.authorBirkholtz, Lyn-Marie
dc.contributor.emaillbirkholtz@up.ac.zaen_ZA
dc.date.accessioned2021-12-13T05:41:00Z
dc.date.available2021-12-13T05:41:00Z
dc.date.issued2021-09
dc.descriptionSupplementary material 1: Figure S1: MMV390048 or MMV642943 chemical structures. Figure S2: Verification of microarray-identified differential gene expression with qPCR analyses (PDF)en_ZA
dc.descriptionSupplementary material 2: Additional Excel File provided with a summary of the full gene expression data set with GO and cluster analyses (XLSX)en_ZA
dc.description.abstractPlease read abstract in the article.en_ZA
dc.description.departmentBiochemistryen_ZA
dc.description.departmentGeneticsen_ZA
dc.description.departmentMicrobiology and Plant Pathologyen_ZA
dc.description.departmentUP Centre for Sustainable Malaria Control (UP CSMC)en_ZA
dc.description.librarianhj2021en_ZA
dc.description.sponsorshipThe South African Medical Research Council and the Department of Science and Innovation South African Research Chairs Initiative Grants managed by the National Research Foundation and the International Society of Infectious diseases Small Grants program.en_ZA
dc.description.urihttps://pubs.acs.org/journal/aidcbcen_ZA
dc.identifier.citationNiemand, J., Van Biljon, R., Van Der Watt, M. et al. 2021, 'Chemogenomic fingerprints associated with stage-specific gametocytocidal compound action against human malaria parasites', ACS Infectious Diseases, vol. 7. no. 10, pp. 2904-2916.en_ZA
dc.identifier.issn2373-8227 (print)
dc.identifier.issn2373-8227 (online)
dc.identifier.other10.1021/acsinfecdis.1c00373
dc.identifier.urihttp://hdl.handle.net/2263/83028
dc.language.isoenen_ZA
dc.publisherAmerican Chemical Societyen_ZA
dc.rights© 2021 The Authors. Published by American Chemical Societyen_ZA
dc.subjectGametocyteen_ZA
dc.subjectDrug responseen_ZA
dc.subjectKinaseen_ZA
dc.subjectStage-specificen_ZA
dc.subjectChemogenomicen_ZA
dc.subjectPlasmodiumen_ZA
dc.titleChemogenomic fingerprints associated with stage-specific gametocytocidal compound action against human malaria parasitesen_ZA
dc.typeArticleen_ZA

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