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Browsing University of Pretoria: Research Output by UP Author "Ismail, Farzana"
Now showing items 1-14 of 14
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Lowe, Michelle; Ehlers, Marthie Magdaleen; Ismail, Farzana; Peirano, Gisele; Becker, Piet J.; Pitout, Johann D.D.; Kock, Marleen M. (Frontiers Media, 2018-06-12)Acinetobacter baumannii is an opportunistic pathogen that is increasingly responsible for hospital-acquired infections. The increasing prevalence of carbapenem resistant A. baumannii has left clinicians with limited ...
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Makhado, Ndivhuho Agnes; Ismail, Farzana; Dangor, Yusuf; Chephe, Tlou J.H.; Hoosen, Anwar Ahmed; Nchabeleng, Maphoshane (MedPharm Publications, 2014)Invasive infections caused by yeasts are associated with high mortality and morbidity, and resistance to antifungal agents is increasing. Candida spp. has emerged as the leading cause of systemic nosocomial fungal infections. ...
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Ismail, Nazir Ahmed; Omar, Shaheed Vally; Moultrie, Harry; Bhyat, Zaheda; Conradie, Francesca; Enwerem, M.; Ferreira, Hannetjie; Hughes, Jennifer; Joseph, Lavania; Kock, Yulene; Letsaolo, Vancy; Maartens, Gary; Meintjes, Graeme; Ngcamu, Dumisani; Okozi, Nana; Padanilam, Xavier; Reuter, Anja; Romero, Rodolfo; Schaaf, Simon; Te Riele, Julian; Variava, Ebrahim; Van der Meulen, Minty; Ismail, Farzana; Ndjeka, Norbert (Elsevier, 2022-04)BACKGROUND : Bedaquiline improves outcomes of patients with rifampicin-resistant and multidrug-resistant (MDR) tuberculosis; however, emerging resistance threatens this success. We did a cross-sectional and longitudinal ...
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Strydom, Kathy-Anne; Ismail, Farzana; Matabane, M.M.Z.; Onwuegbuna, O.; Omar, Shaheed Vally; Ismail, Nabila (American Society for Microbiology, 2015-09)In a head to head comparison of the MTBDRplus Version 2.0 (Hain Lifescience), Xpert® MTB/RIF (Cepheid) and the Anyplex™ MTB/NTM (Seegene) assays we demonstrate equal sensitivity (59/61; 96.7%) and specificity (53/54; ...
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Said, Mohamed; Dangor, Yusuf; Mbelle, Nontombi Marylucy; Sihlabela, A.; Lekalakala, M.R.; Ismail, Farzana (Health and Medical Publishing Group, 2018-12)BACKGROUND. Group B streptococcus (GBS) is a leading cause of invasive disease, particularly in newborns. Seventy-five percent of neonates will be colonised by mothers carrying the organism. Confirmation of maternal ...
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Ismail, Nazir Ahmed; Omar, Shaheed Vally; Joseph, Lavania; Govender, Netricia; Blows, Linsay; Ismail, Farzana; Koornhof, Hendrik; Dreyer, Andries W; Kaniga, Kone; Ndjeka, Norbert (Elsevier, 2018-02)BACKGROUND : Bedaquiline (BDQ) is a novel agent approved for use in combination treatment of multi-drug resistant tuberculosis (MDR-TB).We sought to determine BDQ epidemiological cut-off values (ECVs), define and assess ...
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Ismail, Nazir Ahmed; Ismail, Farzana; Omar, Shaheed Vally; Blows, Linsay; Gardee, Yasmin; Koornhof, Hendrik; Onyebujoh, Philip C. (AOSIS Open Journals, 2018-12-06)BACKGROUND : The World Health Organization End TB Strategy targets for 2035 are ambitious and drug resistant tuberculosis is an important barrier, particularly in Africa, home to over a billion people. OBJECTIVE : We ...
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Ismail, Nazir Ahmed; Ismail, Farzana; Joseph, Lavania; Govender, Netricia; Blows, Linsay; Kaniga, Kone; Omar, Shaheed Vally (Nature Publishing Group, 2020-01-23)Universal drug susceptibility testing (DST) is an important requirement of the End TB Strategy. The Sensititre broth micro-dilution assay (BMD) tests multiple drugs quantitatively. We defined interpretive criteria for ...
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Moyo, Sizulu; Ismail, Farzanah; Van der Walt, Martie; Ismail, Nazir Ahmed; Mkhondo, Nkateko; Dlamini, Sicelo; Mthiyane, Thuli; Chikovore, Jeremiah; Oladimeji, Olanrewaju; Mametja, David; Maribe, Phaleng; Seocharan, Ishen; Ximiya, Phumlani; Law, Irwin; Tadolini, Marina; Zuma, Khangelani; Manda, S.O.M. (Samuel); Sismanidis, Charalambos; Pillay, Y.; Mvusi, Lindiwe (Elsevier, 2022-08)BACKGROUND : Tuberculosis remains an important clinical and public health issue in South Africa, which has one of the highest tuberculosis burdens in the world. We aimed to estimate the burden of bacteriologically confirmed ...
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Wake, Rachel M.; Ismail, Nazir Ahmed; Omar, Shaheed V.; Ismail, Farzanah; Tiemessen, Caroline T.; Harrison, Thomas S.; Jarvis, Joseph N.; Govender, Nelesh (Oxford University Press, 2022-07)The greater mortality risk among people with advanced human immunodeficiency virus disease and cryptococcal antigenemia, despite treatment, indicates an increased susceptibility to other infections. We found that prior ...
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Wake, Rachel M.; Govender, Nelesh; Omar, S.V. (Shaheed Vally); Ismail, Farzanah; Tiemessen, Caroline T.; Harrison, Thomas S.; Jarvis, Joseph N. (Lippincott, Williams & Wilkins, 2022-05)OBJECTIVE : Investigation of the diagnostic yield of urine-based tuberculosis (TB) screening in patients with advanced HIV disease. DESIGN : A cross-sectional screening study SETTING : HIV outpatient clinics and wards ...
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Ndjeka, Norbert; Campbell, Jonathon R.; Meintjes, Graeme; Maartens, Gary; Schaaf, H. Simon; Hughes, Jennifer; Padanilam, Xavier; Reuter, Anja; Romero, Rodolfo; Ismail, Farzanah; Enwerem, Martin; Ferreira, Hannetjie; Conradie, Francesca; Naidoo, Kogieleum; Menzies, Dick (Elsevier, 2022-07)BACKGROUND : There is a need for short and safe all-oral treatment of rifampicin-resistant tuberculosis. We compared outcomes up to 24 months after treatment initiation for patients with rifampicin-resistant tuberculosis ...
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Omar, Shaheed Vally; Joseph, Lavania; Halima M. Said; Ismail, Farzana; Ismail, Nabila; Gwala, Thabisile L.; Ismail, Nazir Ahmed (AOSIS Open Journals, 2019-02-21)South Africa remains challenged with a high tuberculosis burden accompanied by an increase in drug resistant cases. We assessed the use of the Illumina MiSeq, a next-generation sequencing platform for whole genome ...
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Allam, Mushal; Joseph, Lavania; Ismail, Farzana; Said, Halima; Ismail, Nazir Ahmed; Ismail, Arshad; Mtshali, Senzo; Mnyameni, Florah; Goussard, Pierre; Pekeur, Jade C.; Lourens, Adre; Omar, Shaheed Vally (American Society for Microbiology, 2018-01-18)We describe here the draft genome sequence of a Mycobacterium goodii isolate from a pediatric patient in Western Cape, South Africa. To our knowledge, this is the second reported genome of this rapidly growing nontuberculous ...
Now showing items 1-14 of 14