The objective of this study was to investigate spatial patterns of staphylococcal infections and resistance patterns of clinical isolates among dogs from Gauteng province in South Africa. Data from records of 1497 dog clinical samples submitted to a veterinary teaching hospital between 2007 and 2012 were used in the study. Spatial empirical Bayesian smoothed risk maps were used to investigate spatial patterns of staphylococcal infections, antimicrobial resistance (AMR), and multidrug resistance (MDR). Moran's I and spatial scan statistics were used to investigate spatial clusters at municipal and town spatial scales. Significant clusters of staphylococcal infections were identified at both the municipal (Relative Risk [RR] = 1.71, p = 0.003) and town (RR = 1.65, p = 0.039) scales. However, significant clusters of AMR (p = 0.003) and MDR (p = 0.007) were observed only at the town scale. Future larger studies will need to investigate local determinants of geographical distribution of the clusters so as to guide targeted control efforts.
Qekwana, Daniel Nenene; Phophi, Lufuno; Naidoo, Vinny; Oguttu, James Wabwire; Odoi, Agricola(BioMed Central, 2018-07-31)
BACKGROUND : This study investigated the burden and predictors of canine E. coli urinary tract infections (UTI) and
antimicrobial resistance among dogs presented at a veterinary teaching hospital in South Africa, ...
Ismail, Nazir Ahmed; Mvusi, Lindiwe; Nanoo, Ananta; Dreyer, Andries; Omar, Shaheed V.; Babatunde, Sanni; Molebatsi, Thabo; Van der Walt, Martie; Adelekan, Adeboye; Deyde, Varough; Ihekweazu, Chikwe; Madhi, S.A.(Elsevier, 2018-07)
BACKGROUND : Globally, per-capita, South Africa reports a disproportionately high number of cases of multidrug-resistant (MDR) tuberculosis and extensively drug-resistant (XDR) tuberculosis. We sought to estimate the ...
Oguttu, James Wabwire; Qekwana, Daniel Nenene; Odoi, Agricola(Frontiers Media, 2021-01-07)
BACKGROUND : While surveillance of antimicrobial drug resistance is ongoing in human
medicine in South Africa, there is no such activity being performed in veterinary medicine.
As a result, there is a need to investigate ...