Role of plants in anticancer drug discovery

Khazir, Jabeena; Mir, Bilal Ahmad; Pilcher, Lynne A.; Riley, Darren L.

dc.contributor.author	Khazir, Jabeena
dc.contributor.author	Mir, Bilal Ahmad
dc.contributor.author	Pilcher, Lynne A.
dc.contributor.author	Riley, Darren L.
dc.date.accessioned	2017-03-03T06:35:11Z
dc.date.available	2017-03-03T06:35:11Z
dc.date.issued	2014-02
dc.description.abstract	Cancer is one of the major causes of death and the number of new cases, as well as the number of individuals living with cancer, is expanding continuously. Worldwide the alarming rise in mortality rate due to cancer has fuelled the pursuit for effective anticancer agents to combat this disease. Finding novel and efficient compounds of natural origin has been a major point of concern for research in the pharmaceutical sciences. Plants have been seen to possess the potential to be excellent lead structures and to serve as a basis of promising therapeutic agents for cancer treatment. Many successful anti-cancer drugs currently in use or their analogues are plant derived and many more are under clinical trials. This review aims to highlight the invaluable role that plants have played, and continue to play, in the discovery of anticancer agents.	en_ZA
dc.description.department	Chemistry	en_ZA
dc.description.department	Genetics	en_ZA
dc.description.librarian	hb2017	en_ZA
dc.description.sponsorship	We acknowledge the University of Pretoria for Postdoctoral fellowship to J.K. and B.A.M.	en_ZA
dc.description.uri	http://www.elsevier.com/locate/phytol	en_ZA
dc.identifier.citation	Khazir, J, Mir, BA, Pilcher, LA & Riley, DL 2014, 'Role of plants in anticancer drug discovery', Phytochemistry Letters, vol. 7, pp. 173-181.	en_ZA
dc.identifier.issn	1874-3900 (print)
dc.identifier.issn	1876-7486 (online)
dc.identifier.other	10.1016/j.phytol.2013.11.010
dc.identifier.uri	http://hdl.handle.net/2263/59253
dc.language.iso	en	en_ZA
dc.publisher	Elsevier	en_ZA
dc.rights	© 2013 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved. Notice : this is the author’s version of a work that was accepted for publication inPhytochemistry Letters. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. A definitive version was subsequently published in Phytochemistry Letters, vol. 7, pp. 173-181, 2014. doi : 10.1016/j.phytol.2013.11.010.	en_ZA
dc.subject	Cancer	en_ZA
dc.subject	Drugs	en_ZA
dc.subject	Natural products	en_ZA
dc.subject	Plant derived anticancer drugs	en_ZA
dc.title	Role of plants in anticancer drug discovery	en_ZA
dc.type	Postprint Article	en_ZA