Research Articles (Genetics)

Research Articles (Genetics)

 

A collection containing some of the full text peer-reviewed/ refereed articles published by researchers from the Department of Genetics

Recent Submissions

  • Trataris-Rebisz, A.N.; Rossouw, J.; Markotter, Wanda; Frean, J.A.; Weyer, Jacqueline (Health and Medical Publishing Group, 2019-04)
    BACKGROUND. Spotted fever rickettsiosis, also known as tick bite fever (TBF), is a common infectious disease in South Africa (SA). Although the diagnosis of TBF is often based on clinical grounds only, laboratory testing ...
  • Martin-Garcia, J.; Zas, R.; Solla, A.; Woodward, S.; Hantula, J.; Vainio, E.J.; Mullett, M.; Morales-Rodriguez, C.; Vannini, A.; Martinez-Alvarez, P.; Pinto, G.; Alves, A.; Amaral, J.; Wingfield, Michael J.; Fourie, Gerda; Steenkamp, Emma Theodora; Ahumada, R.; Sera, B.; Sanz-Ros, A.V.; Raposo, R.; Elvira-Recuenco, M.; Iturritxa, E.; Gordon, T.R.; Diez, J.J. (Wiley, 2019-06)
    Fusarium circinatum is a highly virulent invasive pathogen that causes the disease commonly known as pine pitch canker (PPC). On mature trees, the most common symptoms of PPC include resin bleeding, resinous cankers, wilting ...
  • Reva, Oleg N.; Rademan, Sunelle; Visagie, M.H. (Michelle Helen); Lebelo, M.T. (Maphuti); Gwangwa, Mokgadi Violet; Klochko, Vitalii V.; Joubert, Anna Margaretha; Lall, Namrita (Future Science, 2019)
    AIM : To determine the computer-predicted anticancer activity of mupirocin and to compare its activities with those determined for another polyene antibiotic, batumin. MATERIALS AND METHODS : Molecular docking, cytotoxicity ...
  • Moyo, Phanankosi; Kunyane, Phaladi; Selepe, Mamoalosi A.; Eloff, Jacobus Nicolaas; Niemand, Jandeli; Louw, Abraham Izak; Maharaj, Vinesh J.; Birkholtz, Lyn-Marie (BioMed Central, 2019-03-08)
    BACKGROUND : Optimal adoption of the malaria transmission-blocking strategy is currently limited by lack of safe and efficacious drugs. This has sparked the exploration of different sources of drugs in search of ...
  • Nel, Wilma Janine; Duong, Tuan A.; De Beer, Z. Wilhelm; Wingfield, Michael J. (Wiley, 2019-06)
    Black root rot caused by the pathogen Thielaviopsis basicola has been known since the mid 1800s. The disease is important on many agricultural and ornamental plant species and has been found in at least 31 countries. Since ...
  • Kuhn, David Norton; Livingstone III, Donald S.; Richards, Jennifer H.; Manosalva, Patricia M.; Van den Berg, Noelani; Chambers, Alan H. (Elsevier, 2019-02)
    Avocado (Persea americana) is an important tropical and subtropical fruit tree crop. Traditional tree breeding programs face the challenges of long generation time and significant expense in land and personnel resources. Avocado ...
  • Taute, Helena; Bester, Megan Jean; Gaspar, A.R.M. (Anabella Regina Marques) (Wiley, 2019-04)
    Antimicrobial peptides (AMPs), Os and Os‐C, have been identified as multifunctional peptides with antibacterial, antiendotoxin, and anti‐inflammatory properties. For further development of Os and Os‐C as therapeutic peptides, ...
  • Klopper, Ronell R.; De Beer, Z. Wilhelm; Smith, Gideon F. (AOSIS Open Journals, 2018-05-23)
    BACKGROUND : A Nomenclature Section meeting to amend the International Code of Nomenclature for algae, fungi and plants is held every six years, a week before the International Botanical Congress. OBJECTIVES : To report ...
  • Wierzbicki, Martin P.; Maloney, Victoria; Mizrachi, Eshchar; Myburg, Alexander Andrew (Frontiers Media, 2019-02)
    Lignocellulosic biomass, encompassing cellulose, lignin and hemicellulose in plant secondary cell walls (SCWs), is the most abundant source of renewable materials on earth. Currently, fast-growing woody dicots such as ...
  • Hergert, Melinda; Le Roux, Kevin; Nel, Louis Hendrik (BioMed Central, 2018-09-10)
    BACKGROUND : Canine rabies has been enzootic in the dog population of the KwaZulu-Natal province of South Africa since the mid-1970s and has been associated with high rates of human exposures and frequent transmissions ...
  • Mohr, Teresa; Aliyu, Habibu; Kuchlin, Raphael; Zwick, Michaela; Cowan, Don A.; Neumann, Anke; De Maayer, Pieter (BioMed Central, 2018)
    BACKGROUND : The facultatively anaerobic thermophile Parageobacillus thermoglucosidasius produces hydrogen gas (H2) by coupling CO oxidation to proton reduction in the water-gas shift (WGS) reaction via a carbon ...
  • Adam, Sumaiya; Coetzee, Melantha; Honey, E.M. (Engela) (Dove Medical Press, 2018)
    Pena–Shokeir syndrome (PSS) type 1, also known as fetal akinesia deformation sequence, is a rare genetic syndrome that almost always results in intrauterine or early neonatal death. It is characterized by markedly decreased ...
  • Dowsett, Leah; Porras, Antonio R.; Kruszka, Paul; Davis, Brandon; Hu, Tommy; Honey, E.M. (Engela); Badoe, Eben; Thong, Meow-Keong; Leon, Eyby; Girisha, Katta M.; Shukla, Anju; Nayak, Shalini S.; Shotelersuk, Vorasuk; Megarbane, Andre; Phadke, Shubha; Sirisena, Nirmala D.; Dissanayake, Vajira H.W.; Ferreira, Carlos R.; Kisling, Monisha S.; Tanpaiboon, Pranoot; Uwineza, Annette; Mutesa, Leon; Tekendo-Ngongang, Cedrik; Wonkam, Ambroise; Fieggen, Karen; Batista, Leticia Cassimiro; Moretti-Ferreira, Danilo; Stevenson, Roger E.; Prijoles, Eloise J.; Everman, David; Clarkson, Kate; Worthington, Jessica; Kimonis, Virginia; Hisama, Fuki; Crowe, Carol; Wong, Paul; Johnson, Kisha; Clark, Robin D.; Bird, Lynne; Masser-Frye, Diane; McDonald, Marie; Willems, Patrick; Roeder, Elizabeth; Saitta, Sulgana; Anyane-Yeoba, Kwame; Demmer, Laurie; Hamajima, Naoki; Stark, Zornitza; Gillies, Greta; Hudgins, Louanne; Dave, Usha; Shalev, Stavit; Siu, Victoria; Ades, Ann; Dubbs, Holly; Raible, Sarah; Kaur, Maninder; Salzano, Emanuela; Jackson, Laird; Deardorff, Matthew; Kline, Antonie; Summar, Marshall; Muenke, Maximilian; Linguraru, Marius George; Krantz, Ian D. (Wiley, 2019-02)
    Cornelia de Lange syndrome (CdLS) is a dominant multisystemic malformation syndrome due to mutations in five genes—NIPBL, SMC1A, HDAC8, SMC3, and RAD21. The characteristic facial dysmorphisms include microcephaly, arched ...
  • Simpson, M.C. (Melissa Claire); Coetzee, Martin Petrus Albertus; Van der Nest, Magrieta Aletta; Wingfield, Michael J.; Wingfield, Brenda D. (Elsevier, 2018-12)
    Mating is central to many fungal life cycles and is controlled by genes at the mating-type (MAT) locus. These genes determine whether the fungus will be self-sterile (heterothallic) or self-fertile (homothallic). Species ...
  • Lu, Yingchang; Beeghly-Fadiel, Alicia; Wu, Lang; Guo, Xingyi; Li, Bingshan; Schildkraut, Joellen M.; Im, HaeKyung; Chen, Yian A.; Permuth, Jennifer B.; Reid, Brett M.; Teer, Jamie K.; Moysich, Kirsten B.; Andrulis, Irene L.; Anton-Culver, Hoda; Arun, Banu K.; Bandera, Elisa V.; Barkardottir, Rosa B.; Barnes, Daniel R.; Benitez, Javier; Bjorge, Line; Brenton, James; Butzow, Ralf; Caldes, Trinidad; Caligo, Maria A.; Campbell, Ian; Chang-Claude, Jenny; Claes, Kathleen B.M.; Couch, Fergus J.; Cramer, Daniel W.; Daly, Mary B.; DeFazio, Anna; Dennis, Joe; Diez, Orland; Domchek, Susan M.; Dörk, Thilo; Easton, Douglas F.; Eccles, Diana M.; Fasching, Peter A.; Fortner, Renée T.; Fountzilas, George; Friedman, Eitan; Ganz, Patricia A.; Garber Judy; Giles, Graham G.; Godwin, Andrew K.; Goldgar, David E.; Goodman, Marc T.; Greene, Mark H.; Gronwald, Jacek; Hamann, Ute; Heitz, Florian; Hildebrandt, Michelle A.T.; Høgdall, Claus K.; Hollestelle, Antoinette; Hulick, Peter J.; Huntsman, David G.; Imyanitov, Evgeny N.; Isaacs, Claudine; Jakubowska, Anna; James, Paul; Karlan, Beth Y.; Kelemen, Linda E.; Kiemeney, Lambertus A.; Kjaer, Susanne K.; Kwong, Ava; Le, Nhu D.; Leslie, Goska; Lesueur, Fabienne; Levine, Douglas A.; Mattiello, Amalia; May, Taymaa; McGuffog, Lesley; McNeish, Iain A.; Merritt, Melissa A.; Modugno, Francesmary; Montagna, Marco; Neuhausen, Susan L.; Nevanlinna, Heli; Nielsen, Finn C.; Nikitina-Zake, Liene; Nussbaum, Robert L.; Offit, Kenneth; Olah, Edith; Olopade, Olufunmilayo I.; Olson, Sara H.; Olsson, Håkan K.; Osorio, Ana; Park, Sue K.; Parsons, Michael T.; Peeters, Petra H.M.; Pejovic, Tanja; Peterlongo, Paolo; Phelan, Catherine M.; Pujana, Miquel Angel; Ramus, Susan J.; Rennert, Gad; Risch, Harvey; Rodriguez, Gustavo C.; Rodríguez-Antona, Cristina; Romieu, Isabelle; Rookus, Matti A.; Rossing, Mary Anne; Rzepecka, Iwona K.; Sandler, Dale P.; Schmutzler, Rita K.; Setiawan, Veronica W.; Sharma, Priyanka; Sieh, Weiva; Simard, Jacques; Singer, Christian F.; Song, Honglin; Southey, Melissa C.; Spurdle, Amanada B.; Sutphen, Rebecca; Swerdlow, Anthony J.; Teixeira, Manuel R.; Teo, Soo H.; Thomassen, Mads; Tischkowitz, Marc; Toland, Amanda E.; Trichopoulou, Antonia; Tung, Nadine; Tworoger, Shelley S.; Jansen van Rensburg, Elizabeth; Vanderstichele, Adriaan; Vega, Ana; Edwards, Digna Velez; Webb, Penelope M.; Weitzel, Jeffrey N.; Wentzensen, Nicolas; White, Emily; Wolk, Alicja; Wu, Anna H.; Yannoukakos, Drakoulis; Zorn, Kristin K.; Gayther, Simon A.; Antoniou, Antonis C.; Berchuck, Andrew; Goode, Ellen L.; Chenevix-Trench, Georgia; Sellers, Thomas A.; Pharoah, Paul D.P.; Zheng, Wei; Long, Jirong (American Association for Cancer Research, 2018-09)
    Large-scale genome-wide association studies (GWAS) have identified approximately 35 loci associated with epithelial ovarian cancer (EOC) risk. The majority of GWAS-identified disease susceptibility variants are located in ...
  • Sungirai, Marvelous; Baron, Samantha; Van der Merwe, Nicolaas Albertus (Albie); Moyo, Doreen Zandile; De Clercq, Patrick; Maritz-Olivier, Christine; Madder, Maxime (Elsevier, 2018-04)
    Recently there was an expansion in the geographic range of Rhipicephalus microplus in Zimbabwe. In order to understand gene flow patterns and population structure in this highly invasive and adaptable cattle tick, a ...
  • Dittrich-Schroder, Gudrun; Hoareau, Thierry B.; Hurley, Brett Phillip; Wingfield, Michael J.; Lawson, S.; Nahrung, H.F.; Slippers, Bernard (Springer, 2018-09)
    Increased rates of movement and the accumulation of insects establishing outside their native range is leading to the ‘global homogenization’ of agricultural and forestry pests. We use an invasive wasp, Leptocybe invasa ...
  • Crous, Pedro W.; Wingfield, Michael J.; Burgess, T.I.; Hardy, G.E.St.J.; Gene, J.; Guarro, J.; Baseia, I.G.; Garcia, D.; Gusmao, L.F.P.; Souza-Motta, C.M.; Thangavel, R.; Adamcík, S.; Barili, A.; Barnes, C.W.; Bezerra, J.D.P.; Bordallo, J.J.; Cano-Lira, J.F.; De Oliveira, R.J.V.; Ercole, E.; Hubka, V.; Iturrieta-Gonzalez, I.; Kubatova, A.; Martín, M.P.; Moreau, P.-A.; Morte, A.; Ordonez, M.E.; Rodríguez, A.; Stchigel, A.M.; Vizzini, A.; Abdollahzadeh, J.; Abreu, V.P.; Adamcíkova, K.; Albuquerque, G.M.R.; Alexandrova, A.V.; Alvarez Duarte, E.; Armstrong-Cho, C.; Banniza, S.; Barbosa, R.N.; Bellanger, J.-M.; Bezerra, J.L.; Cabral, T.S.; Cabon, M.; Caicedo, E.; Cantillo, T.; Carnegie, A.J.; Carmo, L.T.; Castañeda-Ruiz, R.F.; Clement, C.R.; Cmokova, A.; Conceição, L.B.; Cruz, R.H.S.F.; Damm, u.; Da Silva, B.D.B.; Da Silva, G.A.; Da Silva, R.M.F.; De A. Santiago, A.L.C.M.; De Oliveira, L.F.; De Souza, C.A.F.; Deniel, F.; Dima, B.; Dong, G.; Edwards, J.; Felix, C.R.; Fournier, J.; Gibertoni, T.B.; Hosaka, K.; Iturriaga, T.; Jadan, M.; Jany, J.-L.; Jurjevic, Z.; Kolarík, M.; Kusan, I.; Landell, M.F.; Leite Cordeiro, T.R.; Lima, D.X.; Loizides, M.; Luo, S.; Machado, A.R.; Madrid, H.; Magalhaes, O.M.C.; Marinho, P.; Matocec, N.; Mesic, A.; Miller, A.N.; Morozova, O.V.; Neves, R.P.; Nonaka, K.; Novakova, A.; Oberlies, N.H.; Oliveira-Filho, J.R.C.; Oliveira, T.G.L.; Papp, V.; Pereira, O.L.; Perrone, G.; Peterson, S.W.; Pham, T.H.G.; Raja, H.A.; Raudabaugh, D.B.; Rehulka, J.; Rodríguez-Andrade, E.; Saba, M.; Schauflerova, A.; Shivas, R.G.; Simonini, G.; Siqueira, J.P.Z.; Sousa, J.O.; Stajsic, V.; Svetasheva, T.; Tan, Y.P.; Tkalcec, Z.; Ullah, S.; Valente, P.; Valenzuela-Lopez, N.; Abrinbana, M.; Viana Marques, D.A.; Wong, P.T.W.; Xavier de Lima, V.; Groenewald, J.Z. (Naturalis Biodiversity Center, 2018-07-13)
    Novel species of fungi described in this study include those from various countries as follows: Australia, Chaetopsina eucalypti on Eucalyptus leaf litter, Colletotrichum cobbittiense from Cordyline stricta × C. australis ...
  • Phoma, Sandra; Vikram, Surendra; Jansson, Janet K.; Ansorge, Isabelle J.; Cowan, Don A.; Van de Peer, Yves; Makhalanyane, Thulani P. (Nature Publising Group, 2018-07-12)
    Understanding the impact of oceanographic features on marine microbial ecosystems remains a major ecological endeavour. Here we assess microbial diversity, community structure and functional capacity along the Agulhas ...
  • Barnes, Irene; Fourie, Arista; Wingfield, Michael J.; Harrington, T.C.; McNew, D.L.; Sugiyama, L.S.; Luiz, B.C.; Heller, W.P.; Keith, L.M. (Naturalis Biodiversity Center, 2018-03-27)
    The native ˋōhiˋa lehua (Metrosideros polymorpha) has cultural, biological and ecological significance to Hawai`i, but it is seriously threatened by a disease commonly referred to as rapid ˋōhiˋa death (ROD). Preliminary ...

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