Research Articles (Genetics)

Research Articles (Genetics)

 

A collection containing some of the full text peer-reviewed/ refereed articles published by researchers from the Department of Genetics

Recent Submissions

  • Mayoka, Godfrey; Njoroge, Mathew; Okombo, John; Gibhard, Liezl; Sanches-Vaz, Margarida; Fontinha, Diana; Birkholtz, Lyn-Marie; Reader, Janette; Van der Watt, M.E. (Mariette); Coetzer, Theresa L.; Lauterbach, Sonja B.; Churchyard, Alisje; Bezuidenhout, Belinda C.; Egan, Timothy J.; Yeates, Clive Leonard; Wittlin, Sergio; Prudêncio, Miguel; Chibale, Kelly (American Chemical Society, 2019)
    Structure–activity relationship studies involving N-aryl-3-trifluoromethyl pyrido[1,2-a]benzimidazoles (PBI) identified several compounds possessing potent in vitro activities against the asexual blood, liver, and gametocyte ...
  • Zlatković, Milica; Wingfield, Michael J.; Jami, Fahimeh; Slippers, Bernard (Wiley, 2019-01)
    In the past decade, trees and shrubs in the Western Balkans region have been damaged by canker and die‐back disease caused by Botryosphaeriaceae species. These pathogens include Neofusicoccum parvum and Diplodia sapinea. ...
  • Adejoro, F.A. (Festus Adeyemi); Hassen, Abubeker; Thantsha, Mapitsi Silvester (Public Library of Science, 2018-10-25)
    Tannin extracts have wide biological activity in ruminant nutrition. The possibility of masking their bitter taste and enhancing sustained release in the rumen can be achieved through encapsulation. The objectives of ...
  • Stobie, Connor Seamus; Cunningham, Michael J.; Oosthuizen, C.J. (Carel); Bloomer, Paulette (Wiley, 2018-10)
    many years; however, recent trends focus on genome‐wide analyses. One method proposed for calibrating inferences from noisy next‐generation data, such as RAD sequencing, is to compare these results with analyses of ...
  • Welz, Pamela J.; Ramond, Jean-Baptiste; Braun, Lorenz; Vikram, Surendra; Le Roes-Hill, Marilize (Elsevier, 2018-02)
    Heterotrophic bacteria proliferate in organic-rich environments and systems containing sufficient essential nutrients. Nitrogen, phosphorus and potassium are the nutrients required in the highest concentrations. The ratio ...
  • De Maayer, Pieter; Aliyu, Habibu; Cowan, Don A. (Elsevier, 2018-10)
    Bacterial classification at higher taxonomic ranks such as the order and family levels is currently reliant on phylogenetic analysis of 16S rRNA and the presence of shared phenotypic characteristics. However, these may not ...
  • Heydari, Mahdi; Miclotte, Giles; Van de Peer, Yves; Fostier, Jan (BioMed Central, 2018-09-04)
    BACKGROUND : Aligning short reads to a reference genome is an important task in many genome analysis pipelines. This task is computationally more complex when the reference genome is provided in the form of a de Bruijn ...
  • Viljoen, Erika; Odeny, Damaris A.; Coetzee, Martin Petrus Albertus; Berger, David Kenneth; Rees, David J.G. (Springer, 2018-04)
    Amaranthus species are an emerging and promising nutritious traditional vegetable food source. Morphological plasticity and poorly resolved dendrograms have led to the need for well resolved species phylogenies. We ...
  • De Lange, Christo; Coertzen, Dina; Smit, Frans J.; Wentzel, Johannes F.; Wong, Ho Ning; Birkholtz, Lyn-Marie; Haynes, Richard K.; N'Da, David D. (Elsevier, 2018-10)
    Artemisinin-ferrocene conjugates incorporating a 1,2-disubstituted ferrocene analogous to that embedded in ferroquine but attached via a piperazine linker to C10 of the artemisinin were prepared from the piperazine artemisinin ...
  • Jami, Fahimeh; Wingfield, Michael J.; Gryzenhout, Marieka; Slippers, Bernard (Springer Verlag, 2017-11)
    The Botryosphaeriales includes serious plant pathogens with a broad host and geographic distribution globally. In South Africa and Namibia, these fungi include important pathogens of native and non-native woody plants, ...
  • Aylward, Janneke; Wingfield, Brenda D.; Dreyer, Léanne L.; Roets, Francois; Wingfield, Michael J.; Steenkamp, Emma Theodora (Elsevier, 2018-12)
    Genome comparisons of species with distinctive ecological traits can elucidate genetic divergence that influenced their differentiation. The interaction of a microorganism with its biotic environment is largely regulated ...
  • Ibrahim, Mohammed Auwal; Serem, June Cheptoo; Bester, Megan Jean; Neitz, A.W.H. (Albert Walter Herman); Gaspar, A.R.M. (Anabella Regina Marques) (Elsevier, 2019-02)
    Antidiabetic agents with multiple targets have the greatest pharmaceutical potential. In this study, three α-glucosidase inhibitory peptides, PFP, YPL and YPG, were investigated for additional antidiabetic targets viz.; ...
  • Laubscher, M.; Brown, K.; Tonfack, L.B.; Myburg, Alexander Andrew; Mizrachi, Eshchar; Hussey, Steven G. (Nature Publishing Group, 2018-07-20)
    Secondary cell wall (SCW) deposition in Arabidopsis is regulated among others by NAC transcription factors, where SND1 chiefly initiates xylem fibre differentiation while VND6 controls metaxylem vessel SCW development, ...
  • Mokoena, Taole; Smit, J.G.M.; Karusseit, V.O.L. (Otto); Dorfling, Cecilia Maria; Van Rensburg, Elizabeth J. (Wiley, 2018-05)
    No abstract available.
  • Jami, Fahimeh; Marincowitz, Seonju; Slippers, Bernard; Wingfield, Michael J. (Springer, 2018-09)
    Fungi in the Botryosphaeriales (Ascomycetes) are common endophytes in woody plants with a wide global distribution and in some cases they are important tree pathogens. The aim of this study was to consider the possible ...
  • Coetzee, Martin Petrus Albertus; Musasira, N.Y.; Roux, Jolanda; Roets, F.; Van der Merwe, Nicolaas Albertus (Albie); Wingfield, Michael J. (Wiley, 2018-05)
    Signs and symptoms of a disease similar to those of armillaria root rot have recently been observed on various native woody plants on the foothills of Table Mountain in South Africa, one of the most botanically diverse ...
  • Ramsak, Živa; Coll, Anna; Stare, Tjaša; Tzfadia, Oren; Baebler, Špela; Van de Peer, Yves; Gruden, Kristina (American Society of Plant Biologists, 2018-09)
    To develop novel crop breeding strategies, it is crucial to understand the mechanisms underlying the interaction between plants and their pathogens. Network modeling represents a powerful tool that can unravel properties ...
  • Rebbeck, Timothy R.; Friebel, Tara M.; Friedman, Eitan; Hamann, Ute; Huo, Dezheng; Kwong, Ava; Olah, Edith; Olopade, Olufunmilayo I.; Solano, Angela R.; Teo, Soo-Hwang; Thomassen, Mads; Weitzel, Jeffrey N.; Chan, T.L.; Couch, Fergus J.; Goldgar, David E.; Kruse, Torben A.; Palmero, Edenir Inêz; Park, Sue Kyung; Torres, Diana; Jansen van Rensburg, Elizabeth; McGuffog, Lesley; Parsons, Michael T.; Leslie, Goska; Aalfs, Cora M.; Abugattas, Julio; Adlard, Julian; Agata, Simona; Aittomäki, Kristiina; Andrews, Lesley; Andrulis, Irene L.; Arason, Adalgeir; Arnold, Norbert; Arun, Banu K.; Asseryanis, Ella; Auerbach, Leo; Azzollini, Jacopo; Balmaña, Judith; Barile, Monica; Barkardottir, Rosa B.; Barrowdale, Daniel; Benitez, Javier; Berger, Andreas; Berger, Raanan; Blanco, Amie M.; Blazer, Kathleen R.; Blok, Marinus J.; Bonadona, Valérie; Bonanni, Bernardo; Bradbury, Angela R.; Brewer, Carole; Buecher, Bruno; Buys, Saundra S.; Caldes, Trinidad; Caliebe, Almuth; Caligo, Maria A.; Campbell, Ian; Caputo, Sandrine M.; Chiquette, Jocelyne; Chung, Wendy K.; Claes, Kathleen B.; Collée, J. Margriet; Cook, Jackie; Davidson, Rosemarie; De la Hoya, Miguel; De Leeneer, Kim; De Pauw, Antoine; Delnatte, Capucine; Diez, Orland; Ding, Yuan Chun; Ditsch, Nina; Domchek, Susan M.; Dorfling, Cecilia Maria; Velazquez, Carolina; Dworniczak, Bernd; Eason, Jacqueline; Easton, Douglas F.; Eeles, Ros; Ehrencrona, Hans; Ejlertsen, Bent; EMBRACE; Engel, Christoph; Engert, Stefanie; Evans, D. Gareth; Faivre, Laurence; Feliubadaló, Lidia; Ferrer, Sandra Fert; Foretova, Lenka; Fowler, Jeffrey; Frost, Debra; Galvão, Henrique C.R.; Ganz, Patricia A.; Garber, Judy; Gauthier-Villars, Marion; Gehrig, Andrea; GEMO Study Collaborators; Gerdes, Anne-Marie; Gesta, Paul; Giannini, Giuseppe; Giraud, Sophie; Glendon, Gord; Godwin, Andrew K.; Greene, Mark H.; Gronwald, Jacek; Gutierrez-Barrera, Angelica; Hahnen, Eric; Hauke, Jan; HEBON; Henderson, Alex; Hentschel, Julia; Hogervorst, Frans B.L.; Honisch, Ellen; Imyanitov, Evgeny N.; Isaacs, Claudine; Izatt, Louise; Izquierdo, Angel; Jakubowska, Anna; James, Paul; Janavicius, Ramunas; Jensen, Uffe Birk; John, Esther M.; Vijai, Joseph; Kaczmarek, Katarzyna; Karlan, Beth Y.; Kast, Karin; KConFab Investigators; Kim, Sung-Won; Konstantopoulou, Irene; Korach, Jacob; Laitman, Yael; Lasa, Adriana; Lasset, Christine; Lazaro, Conxi; Lee, Annette; Lee, Min Hyuk; Lester, Jenny; Lesueur, Fabienne; Liljegren, Annelie; Lindor, Noralane M.; Longy, Michel; Loud, Jennifer T.; Lu, Karen H.; Lubinski, Jan; Machackova, Eva; Manoukian, Siranoush; Mari, Véronique; Martinez-Bouzas, Cristina; Matrai, Zoltan; Mebirouk, Noura; Meijers-Heijboer, Hanne E.J.; Meindl, Alfons; Mensenkamp, Arjen R.; Mickys, Ugnius; Miller, Austin; Montagna, Marco; Moysich, Kirsten B.; Mulligan, Anna Marie; Musinsky, Jacob; Neuhausen, Susan L.; Nevanlinna, Heli; Ngeow, Joanne; Nguyen, Huu Phuc; Niederacher, Dieter; Nielsen, Henriette Roed; Nielsen, Finn Cilius; Nussbaum, Robert L.; Offit, Kenneth; Ofverholm, Anna; Ong, Kai-ren; Osorio, Ana; Papi, Laura; Papp, Janos; Pasini, Barbara; Pedersen, Inge Sokilde; Peixoto, Ana; Peruga, Nina; Peterlongo, Paolo; Pohl, Esther; Pradhan, Nisha; Prajzendanc, Karolina; Prieur, Fabienne; Pujol, Pascal; Radice, Paolo; Ramus, Susan J.; Rantala, Johanna; Rashid, Muhammad Usman; Rhiem, Kerstin; Robson, Mark; Rodriguez, Gustavo C.; Rogers, Mark T.; Rudaitis, Vilius; Schmidt, Ane Y.; Schmutzler, Rita Katharina; Senter, Leigha; Shah, Payal D.; Sharma, Priyanka; Side, Lucy E.; Simard, Jacques; Singer, Christian F.; Skytte, Anne-Bine; Slavin, Thomas P.; Snape, Katie; Sobol, Hagay; Southey, Melissa; Steele, Linda; Steinemann, Doris; Sukiennicki, Grzegorz; Sutter, Christian; Szabo, Csilla I.; Tan, Yen Y.; Teixeira, Manuel R.; Terry, Mary Beth; Teule, Alex; Thomas, Abigail; Thull, Darcy L.; Tischkowitz, Marc; Tognazzo, Silvia; Toland, Amanda Ewart; Topka, Sabine; Trainer, Alison H.; Tung, Nadine; Van Asperen, Christi J.; Van der Hout, Annemieke H.; Van der Kolk, Lizet E.; Van der Luijt, Rob B.; Van Heetvelde, Mattias; Varesco, Liliana; Varon-Mateeva, Raymonda; Vega, Ana; Villarreal-Garza, Cynthia; Von Wachenfeldt, Anna; Walker, Lisa; Wang-Gohrke, Shan; Wappenschmidt, Barbara; Weber, Bernhard H.F.; Yannoukakos, Drakoulis; Yoon, Sook-Yee; Zanzottera, Cristina; Zidan, Jamal; Zorn, Kristin K.; Hutten Selkirk, Christina G.; Hulick, Peter J.; Chenevix-Trench, Georgia; Spurdle, Amanda B.; Antoniou, Antonis C.; Nathanson, Katherine L. (Wiley, 2018-05)
    The prevalence and spectrum of germline mutations in BRCA1 and BRCA2 have been reported in single populations, with the majority of reports focused on White in Europe and North America. The Consortium of Investigators of ...
  • Visser, Erik A.; Wegrzyn, Jill L.; Myburg, Alexander Andrew; Naidoo, Sanushka (BioMed Central, 2018-08-23)
    BACKGROUND : Fusarium circinatum is a pressing threat to the cultivation of many economically important pine tree species. Efforts to develop effective disease management strategies can be aided by investigating the ...
  • Naalden, Diana; Haegeman, Annelies; De Almeida-Engler, Janice; Birhane Eshetu, Firehiwot; Bauters, Lander; Gheysen Godelieve (Wiley, 2018-07)
    On invasion of roots, plant‐parasitic nematodes secrete effectors to manipulate the cellular regulation of the host to promote parasitism. The root‐knot nematode Meloidogyne graminicola is one of the most damaging nematodes ...

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