Screening of Venda medicinal plants for antifungal activity against Candida albicans

Fernandes, Anthony C.; Jansen van Rensburg, Connie E.; Steenkamp, Vanessa

dc.contributor.author	Fernandes, Anthony C.
dc.contributor.upauthor	Jansen van Rensburg, Connie E.
dc.contributor.upauthor	Steenkamp, Vanessa
dc.date.accessioned	2008-06-02T07:55:39Z
dc.date.available	2008-06-02T07:55:39Z
dc.date.issued	2007-04
dc.description.abstract	Crude methanol and water extracts of 32 plant species, used for the treatment of infectious diseases in Venda, were screened for in vitro activity against Candida albicans standard strain (ATCC 10231) and five clinical isolates. Water extracts of 16 plant species and methanol extracts of 11 plant species inhibited candidiasis growth. Inhibition at < 1 mg/ml, against the C. albicans strains tested, was observed for the methanol extracts of Combretum molle (root), Piper capense (bark), Solanum aculeastrum (fruits), Syzygium cordatum (bark) and Zanthoxylum davyi (bark) as well as the aqueous bark extract of Afzelia quanzensis and root extract of Tabernaemontana elegans. These results implicate that the extracts contain compounds with therapeutic potential against C. albicans.	en
dc.description.sponsorship	National Research Foundation	en
dc.format.extent	187277 bytes
dc.format.mimetype	application/pdf
dc.identifier.citation	Steenkamp, V, Fernandes, AC & Van Rensburg, CEJ 2007, 'Screening of Venda medicinal plants for antifungal activity against Candida albicans', South African Journal of Botany, vol. 73, no. 2, pp. 256-258. [http://www.sciencedirect.com/science/journal/02546299]	en
dc.identifier.issn	0254-6299
dc.identifier.other	10.1016/j.sajb.2006.11.003
dc.identifier.uri	http://hdl.handle.net/2263/5745
dc.language.iso	en	en
dc.publisher	Elsevier	en
dc.rights	Elsevier	en
dc.subject	Antifungal activity	en
dc.subject	Candida albicans	en
dc.subject	Traditional medicine	en
dc.subject	Venda	en
dc.subject.lcsh	Medicinal plants
dc.subject.lcsh	Venda (African people)
dc.subject.lcsh	Candida albicans -- Therapeutics
dc.subject.lcsh	Syzygium cordatum
dc.subject.lcsh	Antifungal agents
dc.subject.lcsh	Methanol -- Extracts
dc.title	Screening of Venda medicinal plants for antifungal activity against Candida albicans	en
dc.type	Postprint Article	en