Browsing Workspace (UPSpace) by UP Author "Newton, Claire L."

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Functional rescue of inactivating mutations of the human neurokinin 3 receptor using pharmacological chaperones

Anderson, Ross Calley; Hanyroup, Sharika; Song, Yong Bhum; Mohamed-Moosa, Zulfiah; Van den Bout, Iman; Schwulst, Alexis C.; Kaiser, Ursula B.; Millar, Robert P.; Newton, Claire L. (MDPI, 2022-04-21)

G protein-coupled receptors (GPCRs) facilitate the majority of signal transductions across cell membranes in humans, with numerous diseases attributed to inactivating GPCR mutations. Many of these mutations result in ...
Provocative tests with Kisspeptin-10 and GnRH set the scene for determining social status and environmental impacts on reproductive capacity in male African lions (Panthera leo)

Ludwig, Mike; Newton, Claire L.; Pieters, Ane; Homer, Natalie Z.M.; Li, Xiao Feng; O'Byrne, Kevin T.; Millar, Robert P. (Elsevier, 2022-12)

Understanding the hypothalamic factors regulating reproduction facilitates maximising the reproductive success of breeding programmes and in the management and conservation of threatened species, including African lions. ...

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