Min, Jie; Ma, Feiyang; Seyran, Berfin; Pellegrini, Matteo; Greeff, O.B.W. (Oppel Bernhardt Wilhelm); Moncada, Salvador; Tudzarova, Slavica
(Nature Research, 2022-03-22)
HIF1α and PFKFB3 play a critical role in the survival of damaged β-cells in type–2 diabetes
while rendering β-cells non-responsive to glucose stimulation. To discriminate the role of
PFKFB3 from HIF1α in vivo, we generated ...