Studies on Haemonchus contortus. VI. Attempts to stimulate immunity to abomasal trichostrongylids in Merino sheep
Reinecke, R.K.; De Villiers, I.L.; Bruckner, Christel; Steyn, P.J.J.; Bigalke, R.D.; Cameron, Colin McKenzie; Gilchrist, Frances M.C.; Jordaan, E.; Morren, A.J.; Verster, Anna J.M.; Verwoerd, Daniel Wynand; Walker, Jane B.
Two doses of infective larvae of 20 000 Trichostrongylus axei, dosed to Merino lambs at an interval of 14 days and subsequently challenged with Ostertagia circumcincta, caused a significant reduction (P < 0,01) in the establishment of 5th and adult stages of the latter. T. axei was unable to protect Merino sheep against homologous challenge nor was Haemonchus contortus a successful vaccine against challenge with the same species. The vaccinated group showed a reduction (P < 0,025) only in 5th and adult H. contortus, but not in the total worm burdens.
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