Leukoencephalomalacia in two horses induced by oral dosing of fumonisin B₁

Kellerman, T. Stephanus; Marasas, Walter F.O. (Walter Friedrich Otto); Thiel, P.G.; Gelderblom, W.C.A.; Cawood, M.; Coetzer, Jacobus A.W.

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1990 Onderstepoort Journal of Veterinary Research, Volume 57, 1990
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dc.contributor.author	Kellerman, T. Stephanus
dc.contributor.author	Marasas, Walter F.O. (Walter Friedrich Otto)
dc.contributor.author	Thiel, P.G.
dc.contributor.author	Gelderblom, W.C.A.
dc.contributor.author	Cawood, M.
dc.contributor.editor	Verwoerd, Daniel Wynand
dc.contributor.upauthor	Coetzer, Jacobus A.W.
dc.date.accessioned	2014-09-01T10:25:23Z
dc.date.available	2014-09-01T10:25:23Z
dc.date.created	2013
dc.date.issued	1990
dc.description	The articles have been scanned in colour with a HP Scanjet 5590; 600dpi. Adobe Acrobat XI Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format.	en
dc.description.abstract	Leukoencephalomalacia (LEM) was induced by the oral administration of fumonisin B₁ (FB₁) to 2 horses: a filly received 59,5mg/kg of a 50% preparation of FB₁ administered in 21 doses of 1,25-4mg/kg over 33 days; a colt, 44,3mg/kg of 95% pure FB₁ in 20 doses of 1-4 mg/kg in 29 days. Both animals developed nervous signs such as apathy, changes in temperament, inco-ordination, walking into objects, and one showed paralysis of the lips and tongue. Characteristic lesions of LEM were present in the brains. These trials proved conclusively that FB₁ can induce LEM in horses.	en
dc.description.librarian	mn2014
dc.identifier.citation	Kellerman, TS, Marasas, WFO, Thiel, PG, Gelderblom, WCA, Cawood, M & Coetzer, JAW 1990, 'Leukoencephalomalacia in two horses induced by oral dosing of fumonisin B₁’, Onderstepoort Journal of Veterinary Research, vol. 57, no. 4, pp. 269-275.	en
dc.identifier.issn	0330-2465
dc.identifier.uri	http://hdl.handle.net/2263/41861
dc.language.iso	en	en
dc.publisher	Published by the Government Printer, Pretoria.	en
dc.rights	©South Africa. Dept. of Agricultural Technical Services. ©University of Pretoria. Dept. of Library Services (digital).	en
dc.subject	Veterinary medicine	en
dc.subject.lcsh	Veterinary medicine -- South Africa
dc.title	Leukoencephalomalacia in two horses induced by oral dosing of fumonisin B₁	en
dc.type	Article	en