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Browsing Research Articles (UP Centre for Sustainable Malaria Control (UP CSMC)) by Type "Postprint Article"
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Dziwornu, Godwin Akpeko; Coertzen, Dina; Leshabane, Meta Kgaogelo; Korkor, Constance M.; Cloete, Cleavon K.; Njoroge, Mathew; Gibhard, Liezl; Lawrence, Nina; Reader, Janette; Van der Watt, Mariette Elizabeth; Wittlin, Sergio; Birkholtz, Lyn-Marie; Chibale, Kelly
(American Chemical Society, 2021-04)
A novel series of antimalarial benzimidazole derivatives incorporating phenolic Mannich base side chains at the C2 position, which possess dual asexual blood and sexual stage activities, is presented. Structure–activity ...
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Koelmel, Jeremy P.; Lin, Elizabeth Z.; DeLay, Kayley; Williams, Antony J.; Zhou, Yakun; Bornman, Maria S. (Riana); Obida, Muvhulawa; Chevrier, Jonathan; Godri Pollitt, Krystal J.
(American Chemical Society, 2022-01)
Children in low- and middle-income countries are often exposed to higher levels of chemicals and are more vulnerable to the health effects of air pollution. Little is known about the diversity, toxicity, and dynamics of ...
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Huq, Fahmida; Obida, Muvhulawa; Bornman, Maria S. (Riana); Di Lenardo, Thomas Z.; Chevrier, Jonathan
(Elsevier, 2020-06)
Dichlorodiphenyl trichloroethane (DDT) is an organochlorine insecticide that is banned internationally except for use as part of Indoor Residual Spraying (IRS) programs to control malaria. Although animal studies show that ...
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Riddin, Megan A.; Venter, Gert Johannes; Labuschagne, K.; Villet, M.H.
(Wiley, 2019-12)
An upsurge in African horse sickness (AHS) in the Eastern Cape, South Africa, from 2006 led to an epidemiological reassessment of the disease there. Light trapping surveys carried out near horses, donkeys and zebras in ...
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Mphateng, Thabang N.; Mapossa, António Benjamim; Wesley-Smith, James; Ramjee, Shatish; Focke, Walter Wilhelm
(Springer, 2022-05)
This study aimed to develop cellulose-based polymer matrices as controlled release devices for plant-based insect repellents and attractants, with the aim of finding sustainable and environmentally friendly pest control ...
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Patrick, Sean Mark; Cox, Sarah N.; Guidera, Kathryn E.; Simon, Molly J.; Kruger, Taneshka; Bornman, Maria S. (Riana)
(Taylor and Francis, 2022)
The global Coronavirus disease 2019 (COVID-19) pandemic has resulted in public health, political, scientific and private sector response at an unprecedented scale. However, this shift in focus has caused widespread disruption ...
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Riddin, Megan A.; Venter, Gert Johannes; Labuschagne, K.; Villet, M.H.
(Wiley, 2019-12)
African horse sickness (AHS), a disease of equids caused by the AHS virus, is of major concern in South Africa. With mortality reaching up to 95% in susceptible horses and the apparent reoccurrence of cases in regions ...
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Raman, Jaishree; Fakudze, Phelele; Sikaala, Chadwick H.; Chimumbwa, John; Moonasar, Devanand
(Taylor and Francis, 2021)
Four southern Africa countries, namely, Botswana, Eswatini, Namibia and South Africa, were identified by the World Health Organization as having the potential to eliminate malaria in the near future. However, the extreme ...
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Pretorius, Franco; Focke, Walter Wilhelm; Androsch, Rene; Du Toit, Elizabeth Louisa
(Elsevier, 2021-04)
A comprehensive review of refractive index mixing rules of binary solutions is presented. All published mixing rules, with the exception of the Wiener mixing rule, can be reformulated into expressions with a linear dependence ...
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Coertzen, Dina; Reader, Janette; Van der Watt, Mariette Elizabeth; Leshabane, Meta Kgaogelo; Langeveld, Henrico; Cheuka, Peter M.; Dziwornu, Godwin Akpeko; Chibale, Kelly; Birkholtz, Lyn-Marie
(Taylor and Francis, 2021)
The effectiveness of current antimalarial therapies that cure patients of the pathogenic asexual blood stages is rapidly declining due to the spread of antimalarial drug resistance. This requires the development of novel ...
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Mabuza, J. Mcebisi; Kaiser, Marcel; Bapela, Mahwahwatse Johanna
(Elsevier, 2022-11)
ETHNOPHARMACOLOGICAL RELEVANCE : The Vha-Venda people of South Africa use Pappea capensis EckI & Zeyh. (Sapindaceae) twigs to treat malaria and its related symptoms.
AIM OF STUDY : The main aim of this study was to evaluate ...
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Mianda, S.M.; Invernizzi, Luke; Van der Watt, Mariette Elizabeth; Reader, Janette; Moyo, Phanankosi; Birkholtz, Lyn-Marie; Maharaj, Vinesh J.
(Elsevier, 2022-10)
Please abstract in the article.
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An, Sookee; Rauch, Stephen A.; Maphula, Angelina; Obida, Muvhulawa; Kogut, Katherine; Bornman, Maria S. (Riana); Chevrier, Jonathan; Eskenazi, Brenda
(Elsevier, 2022-11)
BACKGROUND : Half the world's population is at risk for malaria. Indoor residual spraying (IRS) with insecticides has been effective in controlling malaria, yet the potential neurotoxicity of these insecticides is of ...
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Elsiwi, Basant; Eskenazi, Brenda; Bornman, Maria S. (Riana); Obida, Muvhulawa; Kim, Joanne; Moodie, Erica E.M.; Mann, Koren K.; Chevrier, Jonathan
(Elsevier, 2024-02)
BACKGROUND :
Pyrethroid insecticides use for indoor residual spraying (IRS) in malaria-endemic areas results in high levels of exposure to local populations. Pyrethroids may cause asthma and respiratory allergies but ...
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Johnson, Todd; Braack, L.E.O.; Guarido, Milehna M.; Venter, Marietjie; Almeida, Antonio Paulo Gouveia
(Wiley, 2020-06)
Most data on species associations and vector potential of mosquitoes in relation to arboviral infections in South Africa date back from the 1940s to late 1990s. Contextual information crucial for disease risk management ...
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Mapossa, António Benjamim; Sitoe, Alcides Everildo José; Focke, Walter Wilhelm; Izadi, Homa; Du Toit, Elizabeth Louisa; Androsch, Rene; Sungkapreecha, Chanita; Van der Merwe, E.M. (Elizabet Margaretha)
(Wiley, 2020-03)
Please read abstract in the article.
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Cheuka, Peter Mubanga; Centani, Luyanda; Arendse, Lauren B.; Fienberg, Stephen; Wambua, Lynn; Renga, Shoneeze S.; Dziwornu, Godwin Akpeko; Kumar, Malkeet; Lawrence, Nina; Taylor, Dale; Wittlin, Sergio; Coertzen, Dina; Reader, Janette; Van der Watt, Mariette Elizabeth; Birkholtz, Lyn-Marie; Chibale, Kelly
(American Chemical Society, 2021-01)
Recent studies on 3,6-diphenylated imidazopyridazines have demonstrated impressive in vitro activity and in vivo efficacy in mouse models of malaria infection. Herein, we report the synthesis and antiplasmodium evaluation ...
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Mambwe, Dickson; Korkor, Constance M.; Mabhula, Amanda; Ngqumba, Zama; Cloete, Cleavon; Kumar, Malkeet; Barros, Paula Ladeia; Leshabane, Meta Kgaogelo; Coertzen, Dina; Taylor, Dale; Gibhard, Liezl; Njoroge, Mathew; Lawrence, Nina; Reader, Janette; Moreira, Diogo Rodrigo; Birkholtz, Lyn-Marie; Wittlin, Sergio; Egan, Timothy J.; Chibale, Kelly
(American Chemical Society, 2022-12)
Please read abstract in the article.
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Mianda, Sephora Mutombo; Moyo, Phanankosi; Maboane, Suzan; Birkholtz, Lyn-Marie; Maharaj, Vinesh J.
(Taylor and Francis, 2024)
Please read abstract in the article.
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Kim, Joanne; Yang, Seungmi; Moodie, Erica E.M.; Obida, Muvhulawa; Bornman, Maria S. (Riana); Eskenazi, Brenda; Chevrier, Jonathan
(Lippincott Williams and Wilkins, 2022-07)
BACKGROUND : Dichlorodiphenyltrichloroethane (DDT) or pyrethroid insecticides are sprayed inside dwellings for malaria vector control, resulting in high exposure to millions of people, including pregnant women. These ...