• School and community driven dengue vector control and monitoring in Myanmar : study protocol for a cluster randomized controlled trial 

  Overgaard, Hans J.; Linn, Nay Yi Yi; Kyaw, Aye Mon Mon; Braack, L.E.O.; Tin, Myo Win; Bastien, Sheri; Velde, Fiona Vande; Echaubard, Pierre; Zaw, Win; Mukaka, Mavuto; Maude, Richard (Taylor and Francis, 2023-08)

  BACKGROUND : Dengue is the most common and widespread mosquito-borne arboviral disease globally estimated to cause >390 million infections and >20,000 deaths annually. There are no effective preventive drugs and the newly ...
• Machine learning approaches identify chemical features for stage-specific antimalarial compounds 

  Van Heerden, Ashleigh; Turon, Gemma; Duran-Frigola, Miquel; Pillay, Nelishia; Birkholtz, Lyn-Marie (American Chemical Society, 2023-11-07)

  Efficacy data from diverse chemical libraries, screened against the various stages of the malaria parasite Plasmodium falciparum, including asexual blood stage (ABS) parasites and transmissible gametocytes, serve as a ...
• Phytoconstituents from Turraea obtusifolia and their antiplasmodial activity 

  Mianda, Sephora Mutombo; Moyo, Phanankosi; Maboane, Suzan; Birkholtz, Lyn-Marie; Maharaj, Vinesh J. (Taylor and Francis, 2024)

  Please read abstract in the article.
• Alpha viruses detected in mosquitoes in the North-Eastern regions of South Africa, 2014 to 2018 

  Guarido, Milenha M.; Meno, Kgothatso Debra; Mendes, Adriano; Riddin, M.A. (Megan); MacIntyre, Caitlin; Manyana, Sontaga; Johnson, Todd; Schrama, Maarten; Gorsich, Erin E.; Brooke, Basil D.; Almeida, Antonio Paulo G.; Venter, Marietjie (MDPI, 2023-02-23)

  The prevalence and distribution of African alphaviruses such as chikungunya have increased in recent years. Therefore, a better understanding of the local distribution of alphaviruses in vectors across the African continent ...
• Geo-epidemiology of malaria incidence in the Vhembe District to guide targeted elimination strategies, South-Africa, 2015-2018 : a local resurgence 

  Dieng, Sokhna; Adebayo-Ojo, Temitope Christina; Kruger, Taneshka; Riddin, Megan A.; Trehard, Helene; Tumelero, Serena; Bendiane, Marc-Karim; De Jager, Christiaan; Patrick, Sean Mark; Bornman, Maria S. (Riana); Gaudart, Jean (Nature Research, 2023)

  In South Africa, the population at risk of malaria is 10% (around six million inhabitants) and concern only three provinces of which Limpopo Province is the most affected, particularly in Vhembe District. As the elimination ...
• Household living conditions and individual behaviours associated with malaria risk : a community-based survey in the Limpopo River Valley, 2020, South Africa 

  Patrick, Sean Mark; Bendiane, Marc-Karim; Kruger, Taneshka; Harris, Bernice Nerine; Riddin, Megan A.; Trehard, Helene; De Jager, Christiaan; Bornman, Maria S. (Riana); Gaudart, Jean (BMC, 2023-05)

  BACKGROUND : Over the past decade, implementation of multiple malaria control strategies in most countries has largely contributed to advance the global malaria elimination agenda. Nevertheless, in some regions, seasonal ...
• COVID-19 and the malaria elimination agenda in Africa : re-shifting the focus 

  Patrick, Sean Mark; Cox, Sarah N.; Guidera, Kathryn E.; Simon, Molly J.; Kruger, Taneshka; Bornman, Maria S. (Riana) (Taylor and Francis, 2022)

  The global Coronavirus disease 2019 (COVID-19) pandemic has resulted in public health, political, scientific and private sector response at an unprecedented scale. However, this shift in focus has caused widespread disruption ...
• Social acceptance of livestock-administered endectocides for malaria control in Vhembe District, Limpopo Province, South Africa 

  Makhanthisa, Takalani Irene; Braack, L.E.O.; Bornman, Maria S. (Riana); Lutermann, Heike (BMC, 2022-10)

  BACKGROUND : Malaria continues to be a leading cause of morbidity and mortality in Africa and conventional malaria control strategies, such as indoor residual spraying and insecticide-treated bed nets, have limited ...
• Making data map-worthy—enhancing routine malaria data to support surveillance and mapping of Plasmodium falciparum anti-malarial resistance in a pre-elimination sub-Saharan African setting : a molecular and spatiotemporal epidemiology study 

  Kagoro, Frank M.; Allen, Elizabeth; Mabuza, Aaron; Workman, Lesley; Magagula, Ray; Kok, Gerdalize; Davies, Craig; Malatje, Gillian; Guerin, Philippe J.; Dhorda, Mehul; Maude, Richard J.; Raman, Jaishree; Barnes, Karen I. (Springer, 2022-06)

  BACKGROUND : Independent emergence and spread of artemisinin-resistant Plasmodium falciparum malaria have recently been confirmed in Africa, with molecular markers associated with artemisinin resistance increasingly detected. ...
• Could a culturally and age-appropriate song contribute towards malaria prevention in primary school learners? 

  Anderson, Chad M.; Eloff, Irma F.; Kruger, Taneshka (BMC, 2022-04)

  BACKGROUND : Although it is a preventable disease, malaria continues to present one of the major global health challenges. The disease is especially deadly to children under the age of 5 years. This is partly due to the ...
• Maternal exposure to DDT, DDE, and pyrethroid insecticides for malaria vector control and hypospadias in the VHEMBE birth cohort study, Limpopo, South Africa 

  Bornman, Maria S. (Riana); Acerini, Carlo L.; Chevrier, Jonathan; Rauch, Stephen A.; Crause, Madelein; Obida, Muvhulawa; Eskenazi, Brenda (Elsevier, 2022-11)

  Hypospadias is the ectopic opening of the urethra on the penis or scrotum. Exposure to estrogenic and/or anti-androgenic chemicals in utero may play an etiologic role. DDT and the pyrethroids cypermethrin and deltamethrin, ...
• Cellulose acetate/organoclay nanocomposites as controlled release matrices for pest control applications 

  Mphateng, Thabang N.; Mapossa, António Benjamim; Wesley-Smith, James; Ramjee, Shatish; Focke, Walter Wilhelm (Springer, 2022-05)

  This study aimed to develop cellulose-based polymer matrices as controlled release devices for plant-based insect repellents and attractants, with the aim of finding sustainable and environmentally friendly pest control ...
• In vitro dual activity of Aloe marlothii roots and its chemical constituents against Plasmodium falciparum asexual and sexual stage parasites 

  Mianda, S.M.; Invernizzi, Luke; Van der Watt, Mariette Elizabeth; Reader, Janette; Moyo, Phanankosi; Birkholtz, Lyn-Marie; Maharaj, Vinesh J. (Elsevier, 2022-10)

  Please abstract in the article.
• New transmission-selective antimalarial agents through hit-to-lead optimization of 2-([1,1 '-Biphenyl]-4-carboxamido)benzoic acid derivatives 

  Reader, Janette; Opperman, Daniel; Van der Watt, Mariette Elizabeth; Theron, Anjo; Leshabane, Meta Kgaogelo; Da Rocha, Michelle; Turner, Jonathan; Garrabrant, Kathleen; Pina, Ivett; Mills, Catherine; Woster, Patrick M.; Birkholtz, Lyn-Marie (Wiley, 2022-11)

  Malaria elimination requires multipronged approaches, including the application of antimalarial drugs able to block humanto- mosquito transmission of malaria parasites. The transmissible gametocytes of Plasmodium ...
• The influence of a song on school children’s knowledge growth for sustainable malaria prevention 

  Anderson, Chad M.; Kruger, Taneshka; Eloff, Irma (MDPI, 2022-11-14)

  Music as a potential prevention strategy can play a pivotal role in developing behavioural changes and creating awareness about malaria and malaria prevention. The study was conducted in a moderate-risk malaria district ...
• Novel 3-trifluoromethyl-1,2,4-oxadiazole analogues of astemizole with multi-stage antiplasmodium activity and in vivo efficacy in a Plasmodium berghei mouse malaria infection model 

  Mambwe, Dickson; Korkor, Constance M.; Mabhula, Amanda; Ngqumba, Zama; Cloete, Cleavon; Kumar, Malkeet; Barros, Paula Ladeia; Leshabane, Meta Kgaogelo; Coertzen, Dina; Taylor, Dale; Gibhard, Liezl; Njoroge, Mathew; Lawrence, Nina; Reader, Janette; Moreira, Diogo Rodrigo; Birkholtz, Lyn-Marie; Wittlin, Sergio; Egan, Timothy J.; Chibale, Kelly (American Chemical Society, 2022-12)

  Please read abstract in the article.
• Discriminatory Gleason grade group signatures of prostate cancer : an application of machine learning methods 

  Mokoatle, Mpho; Mapiye, Darlington; Marivate, Vukosi; Hayes, Vanessa M.; Bornman, Maria S. (Riana) (Public Library of Science, 2022-06-09)

  One of the most precise methods to detect prostate cancer is by evaluation of a stained biopsy by a pathologist under a microscope. Regions of the tissue are assessed and graded according to the observed histological ...
• Entomological outcomes of clusterrandomised, community-driven dengue vector-suppression interventions in Kampong Cham province, Cambodia 

  Bigio, Jacob; Braack, L.E.O.; Chea, Thy; Set, Srun; Suon, Sokha; Echaubard, Pierre; Hustedt, John; Debackere, Mark; Ramirez, Bernadette; Prasetyo, Didot Budi; Bunleng, Sam; Wharton-Smith, Alexandra; Hii, Jeffrey (Public Library Science, 2022-01-25)

  Cambodia has one of the highest dengue infection rates in Southeast Asia. Here we report quantitative entomological results of a large-scale cluster-randomised trial assessing the impact on vector populations of a package ...
• Adapt or die : targeting unique transmission-stage biology for malaria elimination 

  Van der Watt, Mariette Elizabeth; Reader, Janette; Birkholtz, Lyn-Marie (Frontiers Media S.A., 2022-06-09)

  Plasmodium parasites have a complex life cycle that includes development in the human host as well as the Anopheles vector. Successful transmission of the parasite between its host and vector therefore requires the ...
• Maintaining focus on administering effective malaria treatment during the COVID-19 pandemic 

  Raman, Jaishree; Barnes, K.I.; Baker, L.; Blaylock, M.; Blumberg, Lucille Hellen; Frean, J.; Misiani, E.; Ukpe, I.S. (Indongesit Sunday) (Health and Medical Publishing Group, 2021-01)

  As September marks the start of the malaria season in South Africa (SA), it is essential that healthcare professionals consider both COVID19 and malaria when a patient who lives in or has recently travelled to a malaria ...

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