Browsing Research Articles (UP Centre for Sustainable Malaria Control (UP CSMC)) by Author "Ottilie, Sabine"

Browsing Research Articles (UP Centre for Sustainable Malaria Control (UP CSMC)) by Author "Ottilie, Sabine"

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  • Multistage and transmission-blocking targeted antimalarials discovered from the open-source MMV Pandemic Response Box 
    Reader, Janette; Van der Watt, Mariette Elizabeth; Taylor, Dale; Le Manach, Claire; Mittal, Nimisha; Ottilie, Sabine; Theron, Anjo; Moyo, Phanankosi; Erlank, Erica; Nardini, Luisa; Venter, Nelius; Lauterbach, Sonja; Bezuidenhout, Belinda; Horatscheck, Andre; Van Heerden, Ashleigh; Spillman, Natalie J.; Cowell, Anne N.; Connacher, Jessica I.; Opperman, Daniel; Orchard, Lindsey M.; Llinas, Manuel; Istvan, Eva S.; Goldberg, Daniel E.; Boyle, Grant A.; Calvo, David; Mancama, Dalu; Coetzer, Theresa L.; Winzeler, Elizabeth A.; Duffy, James; Koekemoer, Lizette L.; Basarab, Gregory; Chibale, Kelly; Birkholtz, Lyn-Marie (Nature Publishing Group, 2021-01)
    Chemical matter is needed to target the divergent biology associated with the different life cycle stages of Plasmodium. Here, we report the parallel de novo screening of the Medicines for Malaria Venture (MMV) Pandemic ...
  • Semi-synthetic analogues of cryptolepine as a potential source of sustainable drugs for the treatment of malaria, human African trypanosomiasis, and cancer 
    Abacha, Yabalu Z.; Forkuo, Arnold Donkor; Gbedema, Stephen Y.; Mittal, Nimisha; Ottilie, Sabine; Rocamora, Frances; Winzeler, Elizabeth A.; Van Schalkwyk, Donelly A.; Kelly, John M.; Taylor, Martin C.; Reader, Janette; Birkholtz, Lyn-Marie; Lisgarten, David R.; Cockcroft, Jeremy K.; Lisgarten, John N.; Palmer, Rex A.; Talbert, Rosemary C.; Shnyder, Steven D.; Wright, Colin W. (Frontiers Media, 2022-04)
    The prospect of eradicating malaria continues to be challenging in the face of increasing parasite resistance to antimalarial drugs so that novel antimalarials active against asexual, sexual, and liver-stage malaria parasites ...