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Showing 100 out of a total of 164 results for collection: Theses and Dissertations (Biochemistry).
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Anti-tuberculosis drug design based on a possible mimicry between host and pathogen lipids
Unknown author
(
University of Pretoria
,
2006-05-19
)
Sexual differentiation of malaria parasites is controlled by unique epigenomic and proteomic cascades as revealed by comparative functional genome analyses
Unknown author
(
University of Pretoria
,
2017
)
In-silico gene mining, characterisation and the phylogenetic relationships of bacteriocins from selected phyla
Unknown author
(
University of Pretoria
,
2018
)
Structure-based inhibitor design and validation : application to Plasmodium falciparum glutathione S-transferase
Unknown author
(
University of Pretoria
,
2008-08-07
)
Targeted inhibition of the Plasmodium falciparum Vitamin B6 producing enzyme Pdx1 and the biochemical and functional consequences thereof
Unknown author
(
University of Pretoria
,
2013
)
Development of a generic, structural bioinformatics information management system and its application to variation in foot-and-mouth disease virus proteins
Unknown author
(
University of Pretoria
,
2009-06-02
)
Isolation and cahracterization of antibacterial peptides from hemolymph of the soft tick, Ornithodoros savignyi
Unknown author
(
University of Pretoria
,
2002
)
A Combined functional genomics and in silico approach for the identification of anti-Rhipicephalus vaccine candidates
Unknown author
(
University of Pretoria
,
2013
)
Inhibition of Xanthine oxidase by catechins for tea (Camellia sinensis)
Unknown author
(
University of Pretoria
,
2007-04-07
)
Amphotericin B as a mycolic acid specific targeting agent in tuberculosis
Unknown author
(
University of Pretoria
,
2008-07-04
)
Structural model and properties of AdoMetDc domain of the bifunctional Plasmodium falciparum S-adenosylmethionine decarboxylase/Ornithine decarboxylase
Unknown author
(
University of Pretoria
,
2005-05-19
)
Assessment of mycolic acids as ligand for nanoencapsulated anti-tuberculosis drug targeting
Unknown author
(
University of Pretoria
,
2010-10-23
)
Immunohistochemical localisation of caffeine in young tea (Camellia sinensis (L.) O. Kuntze) leaves
Unknown author
(
University of Pretoria
,
2012
)
Development of new computational approaches for analysis and visualization of fluxes of genomic islands through bacterial species
Unknown author
(
University of Pretoria
,
2015
)
Electrochemical impedance spectroscopy and surface plasmon resonance for diagnostic antibody detection
Unknown author
(
University of Pretoria
,
2012-12-14
)
Properties of anti-mycolic acid antibodies in human tuberculosis patients
Unknown author
(
University of Pretoria
,
2007-02-06
)
An assessment of two evanescent field biosensors in the development of an immunoassay for tuberculosis
Unknown author
(
University of Pretoria
,
2009-06-02
)
Comparison of teaching orientations of an experienced and beginner lecturer in first year Biology
Unknown author
(
University of Pretoria
,
2017
)
Automated structural annotation of the malaria proteome and identification of candidate proteins for modelling and crystallization studies
Unknown author
(
University of Pretoria
,
2008-08-14
)
Towards paper-based micro bio-sensing of biomarker anti-mycolic acid antibodies for TB diagnosis
Unknown author
(
University of Pretoria
,
2019
)
Antibiofilm properties of selected Lactobacillus species and their mechanism of action against Listeria monocytogenes
Unknown author
(
University of Pretoria
,
2022-01
)
Analysis and standardization of marker genotype data for DNA fingerprinting applications
Unknown author
(
University of Pretoria
,
2011-10-24
)
In silico prediction of host-pathogen protein - protein interactions in the malaria parasite, Plasmodium falciparum
Unknown author
(
University of Pretoria
,
2010-09-13
)
Molecular characterization of the hexose transporter (PfHT1) of Plasmodium falciparum in Xenopus laevis oocytes
Unknown author
(
University of Pretoria
,
2005-11-22
)
High-content and super-resolution microscopy reveals the dynamic nuclear architecture and mobile epigenetic marks in Plasmodium falciparum
Unknown author
(
University of Pretoria
,
2012
)
Integrative transcriptome and phenome analysis reveals unique regulatory cascades controlling the intraerythrocytic asexual and sexual development of human malaria parasites
Unknown author
(
University of Pretoria
,
2019
)
Integrating protein annotations for the in silico prioritization of putative drug target proteins in malaria
Unknown author
(
University of Pretoria
,
2012
)
Development of novel computational tools to infer the distribution patterns of bacterial accessory genomic elements and the implications of microevolution towards pathogenicity
Unknown author
(
University of Pretoria
,
2013
)
Mutation status and homology modelling of acaricide-binding proteins in Rhipicephalus ticks
Unknown author
(
University of Pretoria
,
2015
)
Gene expression profiling of polyamine-depleted Plasmodium falciparum
Unknown author
(
University of Pretoria
,
2007
)
Biological activity of Sinularia notanda
Unknown author
(
University of Pretoria
,
2015
)
Genetic engineering of recombinant anti-mycolic acid antibody fragments for use in tuberculosis diagnostics
Unknown author
(
University of Pretoria
,
2012
)
A resonant mirror biosensor approach to understand antibody-antigen interactions in Guillain Barré Syndrome
Unknown author
(
University of Pretoria
,
2008-04-18
)
Transmembrane glycoprotein gp41 of the Human Immunodeficiency Virus Type I : gene synthesis, recombinant expression and immunological characterization
Unknown author
(
University of Pretoria
,
2012-08-14
)
Molecular characterization and in vitro functional analysis of putative immunoprotective molecules in the soft tick, Ornithodoros savignyi
Unknown author
(
University of Pretoria
,
2010-11-01
)
Chemically synthetic mycolic acids as vaccine adjuvants
Unknown author
(
University of Pretoria
,
2014
)
Metabonomics profile and corresponding immune parameters of HIV infected individuals
Unknown author
(
University of Pretoria
,
2012-06-07
)
Anti-inflammatory properties of peptides derived from the carboxy-terminal region of a defensin from the tick Ornithodoros savignyi
Unknown author
(
University of Pretoria
,
2015
)
Development and applications of a novel, thermoresponsive scaffold for three-dimensional cell culture
Unknown author
(
University of Pretoria
,
2013-05-17
)
Biochemical and molecular characterization of putative immunoprotective molecules of the soft tick, Ornithodoros savignyi Audouin (1827)
Unknown author
(
University of Pretoria
,
2011-06-27
)
Immunochemistry of mycolic acid antigens in tuberculosis
Unknown author
(
University of Pretoria
,
2011-05-26
)
Metabolomic markers for agronomic traits and their possible biochemical mechanisms in black tea Camellia sinensis (L.) O. Kuntze
Unknown author
(
University of Pretoria
,
2020-11-17
)
Characterization of genetic diversity in selected cultivars and identification of a possible molecular marker for drought tolerance in tea Camellia sinensis (L.) O. Kuntze
Unknown author
(
University of Pretoria
,
2009-11-03
)
Mass spectrometry metabonomics of HIV-1 sera
Unknown author
(
University of Pretoria
,
2015
)
Bioactivity of metallodrugs
Unknown author
(
University of Pretoria
,
2012
)
Characterizing the immune response to HIV-1 using host derived epitope R7V
Unknown author
(
University of Pretoria
,
2010-11-05
)
New tools for comparative genomics based on oligonucleotide compositional constraints and single nucleotide polymorphisms
Unknown author
(
University of Pretoria
,
2010-06-07
)
Metabolic profiling for identification of potential biomarkers in potato tuber extracts associated with tolerance to Spongospora subterranea f. sp. subterranea infection
Unknown author
(
University of Pretoria
,
2019
)
Pre_GI : a dynamic Catalogue and set of computational tools for the ontology and stratigraphy of horizontally transferred genomic islands in bacterial genomes
Unknown author
(
University of Pretoria
,
2016
)
CRISPR/Cas9 mediated deletion of genes encoding putative cell cycle regulators in Plasmodium falciparum
Unknown author
(
University of Pretoria
,
2017
)
Stratifying antimalarial compounds with similar mode of action using machine learning on chemo-transcriptomic profiles
Unknown author
(
University of Pretoria
,
2019
)
In silico and in vitro inhibition of α- glucosidase and α-amylase by compounds from culinary herbs and spices, for possible treatment of type 2 diabetes
Unknown author
(
University of Pretoria
,
2020
)
Mycobacterial mycolic acids as immunoregulatory lipid antigens in the resistance to tuberculosis
Unknown author
(
University of Pretoria
,
2006-07-05
)
High-throughput prioritization of putative drug targets in the malaria parasite, Plasmodium falciparum
Unknown author
(
University of Pretoria
,
2015
)
Mycolic acid as antigen or analyte in tuberculosis
Unknown author
(
University of Pretoria
,
2009-08-13
)
The effects of medicinal plant extracts on the microbial, biofilm and autolytic activity of several pathogenic bacteria.
Unknown author
(
University of Pretoria
,
2018
)
In vitro antiplasmodial activity of an optimised series of alkylated (bis)urea and (bis)thiourea polyamine analogs
Unknown author
(
University of Pretoria
,
2013
)
In silico discovery of novel cytotoxic T-lymphocyte epitopes in the HIV-1 Pol region in response to antiretroviral resistance mutations
Unknown author
(
University of Pretoria
,
2014
)
Biochemical characterisation of putrescine and spermidine uptake as a potential therapeutic target against the human malaria parasite, Plasmodium falciparum
Unknown author
(
University of Pretoria
,
2012-06-07
)
Bioactivity of a synthetic peptide derived from a defensin from the tick Ornithodoros savignyi Audouin (1827)
Unknown author
(
University of Pretoria
,
2014
)
The design and efficacy of an antisense oligodeoxynucleotide (ODN) targeted against alpha-I-tubulin of Plasmodium falciparum
Unknown author
(
University of Pretoria
,
2007-05-02
)
Biochemical and structural characterization of novel drug targets regulating polyamine biosynthesis in the human malaria parasite, Plasmodium falciparum
Unknown author
(
University of Pretoria
,
2011
)
The effect of mycobacterial mycolic acids on the cytokine profile of the immune response in murine tuberculosis
Unknown author
(
University of Pretoria
,
2005-09-07
)
Functional characterization of a peptide fragment, Os(3-12), derived from the carboxy-terminal region of a defensin from the tick Ornithodoros savignyi
Unknown author
(
University of Pretoria
,
2016
)
Detection of acetone using nanostructured WO3 for diabetes mellitus monitoring applications
Unknown author
(
University of Pretoria
,
2020
)
Comparing biochemical and biophysical methodologies for the characterization of induced cell death
Unknown author
(
University of Pretoria
,
2015
)
Comparison of free and immobilized polyphenol oxidase enzymes for the biocatalytic conversion of catechins into theaflavins
Unknown author
(
University of Pretoria
,
2013-06-28
)
Transcriptome- and proteome-wide responses to putrescine depletion in the human malaria parasite, Plasmodium falciparum
Unknown author
(
University of Pretoria
,
2013
)
Inhibiting amylolytic enzymes by both acarbose and cellobiose as a prelude to treating type II diabetes mellitus
Unknown author
(
University of Pretoria
,
2024-02-14
)
In silico structural characterisation of Plasmodium falciparum dihydro-6-hydroxymethylpterin pyrophosphokinase dihydropteroate synthase (PPPK-DHPS)
Unknown author
(
University of Pretoria
,
2005
)
Inhibition of the histone deacetylase family as a drug target in the human malaria parasite, plasmodium falciparum
Unknown author
(
University of Pretoria
,
2014
)
The effect of herbicides as novel antimalarial drugs on the transcriptome and proteome of Plasmodium falciparum
Unknown author
(
University of Pretoria
,
2011
)
A case study for the de novo genome assembly of plant genomes from Illumina short reads
Unknown author
(
University of Pretoria
,
2018
)
Development of a candidate VP2-based subunit vaccine for African horsesickness virus serotype 5
Unknown author
(
University of Pretoria
,
2005-09-05
)
Two-hybrid analysis and attempted expression of elongation factor 1α from the cattle tick, Rhipicephalus microplus.
Unknown author
(
University of Pretoria
,
2013
)
A reverse genetics approach to evaluate Metzincins as anti-Rhipicephalus microplus tick vaccine candidates
Unknown author
(
University of Pretoria
,
2013
)
Identification of digallated and methylated catechins using UPLC/MS/MS and development of a rapid analysis method for theanine in tea (Camellia sinensis (L.) O. Kuntze) utilizing evaporative light scattering detection
Unknown author
(
University of Pretoria
,
2009
)
Putative extrinsic blood coagulation pathway inhibitors from the tick Ornithodoros savignyi
Unknown author
(
University of Pretoria
,
2006-11-21
)
Development of a dynamic receptor-based pharmacophore model of Plasmodium falciparum spermidine synthase for selective inhibitor identification
Unknown author
(
University of Pretoria
,
2009-06-02
)
The mechanisms regulating exocytosis of the salivary glands of the soft tick,Ornithodoros savignyi
Unknown author
(
University of Pretoria
,
2007-02-15
)
Mathematical modeling of evolutionary changes of oligonucleotide frequency patterns of bacterial genomes for genome-scale phylogenetic inferences
Unknown author
(
University of Pretoria
,
2018
)
Triazolyl Ru(II), Os(II), and Ir(III) complexes as potential HIV-1 entry inhibitors
Unknown author
(
University of Pretoria
,
2021
)
Dynamics of interaction between MA and cholesterol in tuberculosis
Unknown author
(
University of Pretoria
,
2009-11-02
)
Structural and functional analysis of thiaminephosphate and homoserine kinases from Mycobacterium tuberculosis
Unknown author
(
University of Pretoria
,
2017
)
Synthesis structure-activity relationships and biological evaluation of optimised terminally alkylated (bis)urea and (bis)thiourea polyamine analogues as antiplasmodial agents
Unknown author
(
University of Pretoria
,
2017
)
Kinetic analysis of a recombinantly expressed Plasmodium falciparum dihydrofolate synthase-folylpolyglutamate synthase
Unknown author
(
University of Pretoria
,
2007
)
Exploring the evolution of drug resistance in mycobacterium using whole genome sequencing data
Unknown author
(
University of Pretoria
,
2019
)
Functional and structural charaterization of the unique bifunctional enzyme complex involved in regulation of polyamine metabolism in Plasmodium falciparum
Unknown author
(
University of Pretoria
,
2002
)
NMR Metabonomics in an in vitro Model of HIV-1 latency
Unknown author
(
University of Pretoria
,
2017
)
In silico synthesis of analogous lead libraries for drug design by molecular enumeration
Unknown author
(
University of Pretoria
,
2007
)
Structural characterization of EtpA an adhesin from enterotoxigenic Escherichia coli (ETEC)
Unknown author
(
University of Pretoria
,
2016
)
Plasmodium falciparum dihydrofolate synthase (DHFS-FPGS) : gene synthesis and recombinant expression
Unknown author
(
University of Pretoria
,
2006-05-19
)
Gold compounds with anti-HIV and immunomodulatory activity
Unknown author
(
University of Pretoria
,
2011
)
Drought-induced modulation of the Camellia sinensis metabolome
Unknown author
(
University of Pretoria
,
2016
)
Investigating phenotypic differences of Plasmodium falciparum parasites following exposure to classical antimalarial drugs
Unknown author
(
University of Pretoria
,
2018
)
Development and evaluation of a bi-enzymatic nitric oxide reduction system
Unknown author
(
University of Pretoria
,
2013
)
Understanding the contribution of malaria parasites to continued residual malaria in a pre-elimination setting in South Africa : implications for elimination strategies
Unknown author
(
University of Pretoria
,
2018
)
The contribution of Plasmodium falciparum genetic diversity to differentiate drug response in gametocytes
Unknown author
(
University of Pretoria
,
2020
)
Assembly, annotation and polymorphism analysis of a draft transcriptome sequence for a fast-growing Eucalyptus plantation tree
Unknown author
(
University of Pretoria
,
2011-10-24
)
Optimization of the heterologous expression of folate metabolic enzymes of Plasmodium falciparum
Unknown author
(
University of Pretoria
,
2010
)
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UCTD (164)
Malaria (22)
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