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Showing 100 out of a total of 161 results for collection: Theses and Dissertations (Biochemistry).
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Antifungal mode of action studies of an antimicrobial peptide, Os, in planktonic Candida albicans (ATCC 90028)
Unknown author
(
University of Pretoria
,
2020-07
)
Lipid ligand - protein receptor interactions characterised by a resonant mirror biosensor
Unknown author
(
University of Pretoria
,
2007-05-02
)
Discovery and characterization of polyamine analogues as inhibitors of the Plasmodium falciparum polyamine pathway using cheminformatics
Unknown author
(
University of Pretoria
,
2009-09-04
)
Development of a MIAME-compliant microarray data management system for functional genomics data integration
Unknown author
(
University of Pretoria
,
2007-08-22
)
Reverse vaccinology based identification of anti- Rhipicephalus microplus vaccine candidates
Unknown author
(
University of Pretoria
,
2013
)
Inhibition of lysine-specific demethylase 1 as an antimalarial target by polyamine analogues
Unknown author
(
University of Pretoria
,
2015
)
Investigating the anti-inflammatory properties of epigallocatechin gallate from green tea Camellia sinensis (L) O.Kuntze in mammalian innate immunity
Unknown author
(
University of Pretoria
,
2020
)
Identification and characterisation of nucleic acid manipulating enzymes from metaviromic DNA
Unknown author
(
University of Pretoria
,
2019
)
Structural and functional validation of S-adenosylmethionine decarboxylase as a novel drug target in the malaria parasite, Plasmodium falciparum
Unknown author
(
University of Pretoria
,
2014
)
Mathematical simulations and Verhulst modeling of compositional changes in DNA sequences of acquired genomic islands due to bacterial genome amelioration
Unknown author
(
University of Pretoria
,
2014
)
A phage display study of interacting peptide binding partners of malarial S-Adenosylmethionine decarboxylase/Ornithine decarboxylase
Unknown author
(
University of Pretoria
,
2008-07-07
)
Development and application of analysis modules in MADIBA, a Web-based toolkit for the interpretation of microarray data
Unknown author
(
University of Pretoria
,
2009-09-16
)
Molecular characterisation of the ornithine decarboxylase gene of the human malaria parasite, plasmidium falciparum
Unknown author
(
University of Pretoria
,
1998
)
Structure-based drug discovery against a novel antimalarial drug target, S-adenosylmethionine decarboxylase/ornithine decarboxylase
Unknown author
(
University of Pretoria
,
2012
)
Structural and functional characterization of peptides derived from the carboxy-terminal region of a defensin from the tick Ornithodoros savignyi
Unknown author
(
University of Pretoria
,
2013
)
Molecular characterisation of two Ornithodoros savignyi enzyme isoforms belonging to the 5'-nucleotidase family
Unknown author
(
University of Pretoria
,
2009-04-16
)
Transcriptional regulation underlying the quantitative genetic response of maize to grey leaf spot disease
Unknown author
(
University of Pretoria
,
2014
)
Comparative genomics study of completely sequenced Thermus sp. strains to enhance and facilitate their application in biotechnology
Unknown author
(
University of Pretoria
,
2013
)
Anti-tuberculosis drug design based on a possible mimicry between host and pathogen lipids
Unknown author
(
University of Pretoria
,
2006-05-19
)
Dynamic bioinformatics and isotopic evaluation of the permeome of intraerythrocytic Plasmodium falciparum parasites
Unknown author
(
University of Pretoria
,
2018
)
Isolation and cahracterization of antibacterial peptides from hemolymph of the soft tick, Ornithodoros savignyi
Unknown author
(
University of Pretoria
,
2005-10-07
)
High-content and super-resolution microscopy reveals the dynamic nuclear architecture and mobile epigenetic marks in Plasmodium falciparum
Unknown author
(
University of Pretoria
,
2012
)
Sexual differentiation of malaria parasites is controlled by unique epigenomic and proteomic cascades as revealed by comparative functional genome analyses
Unknown author
(
University of Pretoria
,
2017
)
In-silico gene mining, characterisation and the phylogenetic relationships of bacteriocins from selected phyla
Unknown author
(
University of Pretoria
,
2018
)
Structure-based inhibitor design and validation : application to Plasmodium falciparum glutathione S-transferase
Unknown author
(
University of Pretoria
,
2008-08-07
)
Development of novel computational tools to infer the distribution patterns of bacterial accessory genomic elements and the implications of microevolution towards pathogenicity
Unknown author
(
University of Pretoria
,
2013
)
A Combined functional genomics and in silico approach for the identification of anti-Rhipicephalus vaccine candidates
Unknown author
(
University of Pretoria
,
2013
)
Development of a generic, structural bioinformatics information management system and its application to variation in foot-and-mouth disease virus proteins
Unknown author
(
University of Pretoria
,
2009-06-02
)
Mutation status and homology modelling of acaricide-binding proteins in Rhipicephalus ticks
Unknown author
(
University of Pretoria
,
2015
)
Development of a candidate VP2-based subunit vaccine for African horsesickness virus serotype 5
Unknown author
(
University of Pretoria
,
2005-09-05
)
Targeted inhibition of the Plasmodium falciparum Vitamin B6 producing enzyme Pdx1 and the biochemical and functional consequences thereof
Unknown author
(
University of Pretoria
,
2013
)
Generation and analysis of mutated clonal scFv antibody fragments against R7V epitope of HIV-1
Unknown author
(
University of Pretoria
,
2012-11-09
)
Characterizing the immune response to HIV-1 using host derived epitope R7V
Unknown author
(
University of Pretoria
,
2010-11-05
)
Functional perspectives on the evolution of argasid tick salivary gland protein superfamilies
Unknown author
(
University of Pretoria
,
2002
)
In silico structural characterisation of Plasmodium falciparum dihydro-6-hydroxymethylpterin pyrophosphokinase dihydropteroate synthase (PPPK-DHPS)
Unknown author
(
University of Pretoria
,
2005
)
Biochemical and structural characterization of novel drug targets regulating polyamine biosynthesis in the human malaria parasite, Plasmodium falciparum
Unknown author
(
University of Pretoria
,
2011
)
The effect of mycobacterial mycolic acids on the cytokine profile of the immune response in murine tuberculosis
Unknown author
(
University of Pretoria
,
2005-09-07
)
Comparing biochemical and biophysical methodologies for the characterization of induced cell death
Unknown author
(
University of Pretoria
,
2015
)
Transcriptional and post-transcriptional gene regulatory mechanisms in the malaria parasite, Plasmodium falciparum
Unknown author
(
University of Pretoria
,
2010-10-22
)
Mycolic acid as antigen or analyte in tuberculosis
Unknown author
(
University of Pretoria
,
2009-08-13
)
High-throughput prioritization of putative drug targets in the malaria parasite, Plasmodium falciparum
Unknown author
(
University of Pretoria
,
2015
)
Pre_GI : a dynamic Catalogue and set of computational tools for the ontology and stratigraphy of horizontally transferred genomic islands in bacterial genomes
Unknown author
(
University of Pretoria
,
2016
)
NMR Metabonomics in an in vitro Model of HIV-1 latency
Unknown author
(
University of Pretoria
,
2017
)
Structural and functional analysis of thiaminephosphate and homoserine kinases from Mycobacterium tuberculosis
Unknown author
(
University of Pretoria
,
2017
)
Kinetic analysis of a recombinantly expressed Plasmodium falciparum dihydrofolate synthase-folylpolyglutamate synthase
Unknown author
(
University of Pretoria
,
2007
)
Two-hybrid analysis and attempted expression of elongation factor 1α from the cattle tick, Rhipicephalus microplus.
Unknown author
(
University of Pretoria
,
2013
)
Identification of digallated and methylated catechins using UPLC/MS/MS and development of a rapid analysis method for theanine in tea (Camellia sinensis (L.) O. Kuntze) utilizing evaporative light scattering detection
Unknown author
(
University of Pretoria
,
2009
)
In silico and in vitro inhibition of α- glucosidase and α-amylase by compounds from culinary herbs and spices, for possible treatment of type 2 diabetes
Unknown author
(
University of Pretoria
,
2020
)
Mass spectrometry metabonomics of HIV-1 sera
Unknown author
(
University of Pretoria
,
2015
)
Molecular modeling elucidates parasite-specific features of polyamine pathway enzymes of Plasmodium falciparus
Unknown author
(
University of Pretoria
,
2010-11-11
)
New tools for comparative genomics based on oligonucleotide compositional constraints and single nucleotide polymorphisms
Unknown author
(
University of Pretoria
,
2010-06-07
)
Bioactivity of metallodrugs
Unknown author
(
University of Pretoria
,
2012
)
Immunochemistry of mycolic acid antigens in tuberculosis
Unknown author
(
University of Pretoria
,
2011-05-26
)
Development and applications of a novel, thermoresponsive scaffold for three-dimensional cell culture
Unknown author
(
University of Pretoria
,
2013-05-17
)
Biochemical and molecular characterization of putative immunoprotective molecules of the soft tick, Ornithodoros savignyi Audouin (1827)
Unknown author
(
University of Pretoria
,
2011-06-27
)
Mycobacterial mycolic acids as immunoregulatory lipid antigens in the resistance to tuberculosis
Unknown author
(
University of Pretoria
,
2006-07-05
)
CRISPR/Cas9 mediated deletion of genes encoding putative cell cycle regulators in Plasmodium falciparum
Unknown author
(
University of Pretoria
,
2017
)
Stratifying antimalarial compounds with similar mode of action using machine learning on chemo-transcriptomic profiles
Unknown author
(
University of Pretoria
,
2019
)
In vitro antiplasmodial activity of an optimised series of alkylated (bis)urea and (bis)thiourea polyamine analogs
Unknown author
(
University of Pretoria
,
2013
)
Metabonomics profile and corresponding immune parameters of HIV infected individuals
Unknown author
(
University of Pretoria
,
2012-06-07
)
The effects of medicinal plant extracts on the microbial, biofilm and autolytic activity of several pathogenic bacteria.
Unknown author
(
University of Pretoria
,
2018
)
Metabolomic markers for agronomic traits and their possible biochemical mechanisms in black tea Camellia sinensis (L.) O. Kuntze
Unknown author
(
University of Pretoria
,
2020-11-17
)
Characterization of genetic diversity in selected cultivars and identification of a possible molecular marker for drought tolerance in tea Camellia sinensis (L.) O. Kuntze
Unknown author
(
University of Pretoria
,
2009-11-03
)
Functional genomics analysis of the effects of co-inhibition of the malarial S-adenosylmethionine decarboxylase/ornithine decarboxylase
Unknown author
(
University of Pretoria
,
2008
)
Metabolic profiling for identification of potential biomarkers in potato tuber extracts associated with tolerance to Spongospora subterranea f. sp. subterranea infection
Unknown author
(
University of Pretoria
,
2019
)
Lamiaceae plant extracts and isolated compounds demonstrate activity against HIV/AIDS
Unknown author
(
University of Pretoria
,
2013
)
Anti-inflammatory properties of peptides derived from the carboxy-terminal region of a defensin from the tick Ornithodoros savignyi
Unknown author
(
University of Pretoria
,
2015
)
Using oligonucleotide signatures to build a system for effective detection of pathogenic bacteria in metagenomic samples
Unknown author
(
University of Pretoria
,
2009-09-16
)
Metabolomic analyses of the malaria parasite after inhibition of polyamine biosynthesis
Unknown author
(
University of Pretoria
,
2009-10-29
)
Bioinformatic and biotechnological study of biocontrol Bacillus suitable for crop protection and plant growth promotion
Unknown author
(
University of Pretoria
,
2017
)
SSHscreen and SSHdb : software for microarray-based screening and sequence management of cDNA libraries
Unknown author
(
University of Pretoria
,
2010-10-08
)
Metabolomic analysis of maize (Zea mays  L.) seedlings treated with selected plant growth promoting rhizobacteria
Unknown author
(
University of Pretoria
,
2019
)
Proteomic characterization and identification of murine liver and small intestine proteins modulated by tea (Camellia sinensis) consumption
Unknown author
(
University of Pretoria
,
2007-03-15
)
In Silico analysis of malaria parasite databanks for specific genes and motifs associated with immune evasion
Unknown author
(
University of Pretoria
,
2001
)
Plasmodium falciparum dihydrofolate synthase (DHFS-FPGS) : gene synthesis and recombinant expression
Unknown author
(
University of Pretoria
,
2006-05-19
)
Gold compounds with anti-HIV and immunomodulatory activity
Unknown author
(
University of Pretoria
,
2011
)
Investigating the potentially expanded target repertoire of murinized Internalin of Listeria monocytogenes
Unknown author
(
University of Pretoria
,
2016-07-25
)
Basal promoter landscape in Eucalyptus grandis : annotation of distal transcription start sites and core promoter usage
Unknown author
(
University of Pretoria
,
2014
)
Assembly, annotation and polymorphism analysis of a draft transcriptome sequence for a fast-growing Eucalyptus plantation tree
Unknown author
(
University of Pretoria
,
2011-10-24
)
Optimization of the heterologous expression of folate metabolic enzymes of Plasmodium falciparum
Unknown author
(
University of Pretoria
,
2010
)
Proteomic analysis of the humoral antifungal immune response of the soft tick,Ornithodoros savignyi Audouin (1827)
Unknown author
(
University of Pretoria
,
2010-03-12
)
Development and evaluation of a bi-enzymatic nitric oxide reduction system
Unknown author
(
University of Pretoria
,
2013
)
In silico synthesis of analogous lead libraries for drug design by molecular enumeration
Unknown author
(
University of Pretoria
,
2007
)
Structure-function relationships of mycolic acids in tuberculosis
Unknown author
(
University of Pretoria
,
2008-09-22
)
Investigating phenotypic differences of Plasmodium falciparum parasites following exposure to classical antimalarial drugs
Unknown author
(
University of Pretoria
,
2018
)
Modulation of functional properties of bi-functional S-Adenosylmethionine decarboxylase / Ornithine decarboxylase of Plasmodium falciparum by structural motifs in parasite-specific inserts
Unknown author
(
University of Pretoria
,
2009-08-05
)
Inactivation of polyphenol oxidase in Camellia sinensis for the production of high quality instant green tea
Unknown author
(
University of Pretoria
,
2009-08-11
)
Biochemical characterization of the thrombin inhibitor of the tick, Ornithodoros savignyi, and investigation into the expression of its recombinant forms
Unknown author
(
University of Pretoria
,
2007-02-08
)
Structure-function studies of peptide fragments derived from a defensin of the tick Ornithodoros savignyi Audouin (1827)
Unknown author
(
University of Pretoria
,
2013
)
Novel recombinant anti-mycolic acid immunoglobulin tools for improved understanding and management of tuberculosis
Unknown author
(
University of Pretoria
,
2018
)
Structural characterization of EtpA an adhesin from enterotoxigenic Escherichia coli (ETEC)
Unknown author
(
University of Pretoria
,
2016
)
Drought-induced modulation of the Camellia sinensis metabolome
Unknown author
(
University of Pretoria
,
2016
)
The effects of microbacterial mycolic acids on rodent tuberculosis and adjuvant arthritis
Unknown author
(
University of Pretoria
,
2010-06-30
)
Functional and structural charaterization of the unique bifunctional enzyme complex involved in regulation of polyamine metabolism in Plasmodium falciparum
Unknown author
(
University of Pretoria
,
2002
)
Development of a dynamic receptor-based pharmacophore model of Plasmodium falciparum spermidine synthase for selective inhibitor identification
Unknown author
(
University of Pretoria
,
2009-06-02
)
The mechanisms regulating exocytosis of the salivary glands of the soft tick,Ornithodoros savignyi
Unknown author
(
University of Pretoria
,
2007-02-15
)
Inhibition of Xanthine oxidase by catechins for tea (Camellia sinensis)
Unknown author
(
University of Pretoria
,
2007-04-07
)
A case study for the de novo genome assembly of plant genomes from Illumina short reads
Unknown author
(
University of Pretoria
,
2018
)
A reverse genetics approach to evaluate Metzincins as anti-Rhipicephalus microplus tick vaccine candidates
Unknown author
(
University of Pretoria
,
2013
)
Putative extrinsic blood coagulation pathway inhibitors from the tick Ornithodoros savignyi
Unknown author
(
University of Pretoria
,
2006-11-21
)
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UCTD (161)
Malaria (21)
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