Biochemistry

Biochemistry

Recent Submissions

  • Moyo, Phanankosi; Shamburger, William; Van der Watt, M.E. (Mariette); Reader, Janette; De Sousa, Ana Carolina C.; Egan, Timothy J.; Maharaj, Vinesh J.; Bringmann, Gerhard; Birkholtz, Lyn-Marie (Elsevier, 2020-08)
    The discovery and development of multistage antimalarial drugs targeting intra-erythrocytic asexual and sexual Plasmodium falciparum parasites is of utmost importance to achieve the ambitious goal of malaria elimination. Here, ...
  • Kanzi, Aquillah M.; Trollip, Conrad; Wingfield, Michael J.; Barnes, Irene; Van der Nest, Magrieta Aletta; Wingfield, Brenda D. (BioMed Central, 2020-05)
    BACKGROUND: The taxonomic history of Ceratocystis, a genus in the Ceratocystidaceae, has been beset with questions and debate. This is due to many of the commonly used species recognition concepts (e.g., morphological ...
  • Roelofs, Dick; Zwaenepoel, Arthur; Sistermans, Tom; Nap, Joey; Kampfraath, Andries A.; Van de Peer, Yves; Ellers, Jacintha; Kraaijeveld, Ken (BioMed Central, 2020-05)
    BACKGROUND: Gene duplication events play an important role in the evolution and adaptation of organisms. Duplicated genes can arise through different mechanisms, including whole-genome duplications (WGDs). Recently, WGD ...
  • Hoban, Sean; Bruford, Michael; Jackson, Josephine D'Urban; Lopes-Fernandes, Margarida; Heuertz, Myriam; Hohenlohe, Paul A.; Paz-Vinas, Ivan; Sjögren-Gulve, Per; Segelbacher, Gernot; Vernesih, Cristiano; Aitkeni, Sally; Bertola, Laura D.; Bloomer, Paulette; Breed, Martin; Rodríguez-Correa, Hernando; Funk, W. Chris; Grueber, Catherine E.; Hunterp, Margaret E.; Jaffe, Rodolfo; Liggins, Libby; Mergeay, Joachim; Moharrek, Farideh; O'Brien, David; Ogden, Rob; Palma-Silva, Clarisse; Piersona, Jennifer; Ramakrishnan, Uma; Simo-Droissarta, Murielle; Tani, Naoki; Waits, Lisette; Laikre, Linda (Elsevier, 2020-08)
    The 196 parties to the Convention on Biological Diversity (CBD) will soon agree to a post-2020 global framework for conserving the three elements of biodiversity (genetic, species, and ecosystem diversity) while ensuring ...
  • Barnard, Sebastian; Van Goethem, Marc W.; De Scally, S.Z. (Storme); Cowan, Don A.; Jansen van Rensburg, Peet; Claassens, Sarina; Makhalanyane, Thulani P. (Oxford University Press, 2020-04)
    The effects of temperature on microorganisms in high latitude regions, and their possible feedbacks in response to change, are unclear. Here, we assess microbial functionality and composition in response to a substantial ...
  • Makhoba, Xolani Henry; Viegas Junior, Claudio; Mosa, Rebamang A.; Viegas, F.P.D.; Pooe, O.J. (Dove Medical Press, 2020-08)
    It is essential to acknowledge the efforts made thus far to manage or eliminate various disease burden faced by humankind. However, the rising global trends of the socalled incurable diseases continue to put pressure on ...
  • Chang, Runlei; Duong, Tuan A.; Taerum, Stephen J.; Wingfield, Michael J.; Zhou, Xudong; De Beer, Z. Wilhelm (International Mycological Association, 2020-07-30)
    Bark beetle galleries are complex ecosystems where many microbes and other arthropods co-exist with the beetles. Fungi isolated from these galleries are often referred to as ‘beetle associates’, but the nature of these ...
  • Drenkhan, Rein; Ganley, Beccy; Martin-Garcia, Jorge; Vahalík, Petr; Adamson, Kalev; Adamcikova, Katarina; Ahumada, Rodrigo; Blank, Lior; Braganca, Helena; Capretti, Paolo; Cleary, Michelle; Cornejo, Carolina; Davydenko, Kateryna; Diez, Julio J.; Dogmus Lehtijarvi, Hatice Tugba; Dvorak, Milon; Enderle, Rasmus; Fourie, Gerda; Georgieva, Margarita; Ghelardini, Luisa; Hantula, Jarkko; Ioos, Renaud; Iturritxa, Eugenia; Kanetis, Loukas; Karpun, Natalia N.; Koltay, Andras; Landeras, Elena; Markovskaja, Svetlana; Mesanza, Nebai; Milenkovic, Ivan; Musolin, Dmitry L.; Nikolaou, Konstantinos; Nowakowska, Justyna A.; Ogris, Nikica; Oskay, Funda; Oszako, Tomasz; Papazova-Anakieva, Irena; Paraschiv, Marius; Pasquali, Matias; Pecori, Francesco; Rafoss, Trond; Raitelaityte, Kristina; Raposo, Rosa; Robin, Cecile; Rodas, Carlos A.; Santini, Alberto; Sanz-Ros, Antonio V.; Selikhovkin, Andrey V.; Solla, Alejandro; Soukainen, Mirkka; Soulioti, Nikoleta; Steenkamp, Emma Theodora; Tsopelas, Panaghiotis; Vemic, Aleksandar; Vettraino, Anna Maria; Wingfield, Michael J.; Woodward, Stephen; Zamora-Ballesteros, Cristina; Mullett, Martin S. (MDPI Publishing, 2020-07-01)
    Fusarium circinatum, the causal agent of pine pitch canker (PPC), is currently one of the most important threats of Pinus spp. globally. This pathogen is known in many pine-growing regions, including natural and planted ...
  • Chitray, Melanie; Opperman, Pamela A.; Rotherham, Lia; Fehrsen, Jeanni; Van Wyngaardt, Wouter; Frischmuth, Janine; Rieder, Elizabeth; Maree, Francois Frederick (Frontiers Media, 2020-08-11)
    Foot-and-mouth disease (FMD) affects cloven-hoofed domestic and wildlife animals and an outbreak can cause severe losses in milk production, reduction in meat production and death amongst young animals. Several parts of ...
  • Wilson, A.M. (Andi); Wilken, P.M ( Markus); Van der Nest, Magrieta Aletta; Wingfield, Michael J.; Wingfield, Brenda D. (Elsevier, 2020-04)
    Sexual reproduction is a highly conserved feature of the eukaryotes, yet sexual compatibility is determined by a wide variety of mechanisms. In ascomycete fungi, sexual development is controlled by genes at the mating type ...
  • Qu, Evan B.; Omelon, Chris R.; Oren, Aharon; Meslier, Victoria; Cowan, Don A.; Maggs-Kolling, Gillian; DiRuggiero, Jocelyne (Frontiers Media, 2020-01-08)
    Studies of microbial biogeography are often convoluted by extremely high diversity and differences in microenvironmental factors such as pH and nutrient availability. Desert endolithic (inside rock) communities are ...
  • Welgemoed, Tanya; Pierneef, Rian; Sterck, Lieven; Van de Peer, Yves; Swart, Velushka; Scheepers, Kevin Daniel; Berger, David Kenneth (Frontiers Media, 2020-03-13)
    Gray leaf spot (GLS) disease in maize, caused by the fungus Cercospora zeina, is a threat to maize production globally. Understanding the molecular basis for quantitative resistance to GLS is therefore important for food ...
  • Redelinghuys, Mathys J.; Geldenhuys, Janri; Jung, Hyun-Sul; Kock, Marleen M. (Frontiers Media, 2020-08-11)
    A healthy female genital tract harbors a microbiome dominated by lactic acid and hydrogen peroxide producing bacteria, which provide protection against infections by maintaining a low pH. Changes in the bacterial ...
  • Wong, Ho Ning; Padín-Irizarry, Vivian; Van der Watt, M.E. (Mariette); Reader, Janette; Liebenberg, Wilna; Wiesner, Lubbe; Smith, Peter; Eribez, Korina; Winzeler, Elizabeth A.; Kyle, Dennis E.; Birkholtz, Lyn-Marie; Coertzen, Dina; Haynes, Richard K. (Frontiers Media, 2020-01-10)
    We have demonstrated previously that amino-artemisinins including artemiside and artemisone in which an amino group replaces the oxygen-bearing substituents attached to C-10 of the current clinical artemisinin derivatives ...
  • Du Toit, Yves; Coles, Donovin William; Mewalal, Ritesh; Christie, Nanette; Naidoo, Sanushka (Frontiers Media, 2020-02-17)
    Many pests and pathogens threaten Eucalyptus plantations. The study of defense responses in this economically important wood and fiber crop enables the discovery of novel pathways and genes, which may be adopted to improve ...
  • Karolak, Justyna A.; Gambin, Tomasz; Honey, E.M. (Engela); Slavik, Tomas; Popek, Edwina; Stankiewicz, Paweł (BioMed Central, 2020-03-06)
    BACKGROUND : Application of whole genome sequencing (WGS) enables identification of non-coding variants that play a phenotype-modifying role and are undetectable by exome sequencing. Recently, non-coding regulatory single ...
  • Kabwe, Mubanga Helen; Vikram, Surendra; Mulaudzi, Khodani; Jansson, Janet K.; Makhalanyane, Thulani P. (BioMed Central, 2020-08-17)
    BACKGROUND : Understanding the structure and drivers of gut microbiota remains a major ecological endeavour. Recent studies have shown that several factors including diet, lifestyle and geography may substantially shape ...
  • Schalk, Felix; Um, Soohyun; Guo, Huijuan; Kreuzenbeck, Nina B.; Gorls, Helmar; De Beer, Z. Wilhelm; Beemelmanns, Christine (Wiley, 2020-05)
    Herein, we report the targeted isolation and characterization of four linear nonribosomally synthesized tetrapeptides (pseudoxylaramide A–D) and two cyclic nonribosomal peptide synthetase- polyketide synthase-derived ...
  • Compton, Stephen G.; Greeff, Jaco M. (Jacobus Maree) (Wiley, 2020-08)
    Most plants flower and fruit at times of year when probabilities of pollination and seedling establishment are high. Fig trees (Ficus spp.) are often considered as keystone resources for vertebrate frugivores, in part ...
  • Wondafrash, Mesfin; Slippers, Bernard; Nambazimana, Alphonsine; Kayumba, Isaac; Nibouche, Samuel; Van der Lingen, Simon; Asfaw, Birhane A.; Jenya, Herbert; Mutitu, Eston K.; Makowe, Idea A.; Chungu, Donald; Kiwuso, Peter; Kiwuso, Peter; Kulimushi, Emmanuel; Razafindrakotomamonjy, Andrianantenaina; Bosu, Paul P.; Sookar, Preeaduth; Hurley, Brett Phillip (Springer, 2020-07)
    Eucalyptus is one of the most planted tree genera across the world, but is heavily challenged by invasive insect pests originating from the native range of these trees. The rate of introduction of non-native Eucalyptus-feeding ...

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