The united airway - allergy and beyond

Show simple item record Pentz, Adele Moodley, Teshni Green, Robin J. 2013-10-11T07:50:50Z 2013-10-11T07:50:50Z 2013-06
dc.description.abstract The concept of a 'united airway' became popular to link allergic rhinitis and asthma in many individuals who had symptoms of both upper and lower airway disease. Because of the common epithelium that runs all the way down the airway it is not surprising that in many individuals allergens trigger inflammation in both sites. However, the mere fact that some individuals have both symptoms of rhinitis and lower airway pathology does not mean the condition has an atopic basis. Since the airway has a limited number of ways of expressing symptoms, namely runny, sneezy, itchy and blocked nose, as well as cough or wheeze, these symptoms may also be produced in individuals who have quite a long list of other disease states. Although these are less common, healthcare workers will have to consider at some time that symptoms may be from primary ciliary dyskinesia, immune deficiency (primary or secondary), cystic fibrosis, Samter's triad or even recurrent viral airway infections. This article explores these conditions, suggesting their pathophysiology and symptom base. A clear message, to think of one of these conditions if symptoms do not have an allergy base and do not respond to first-line therapy, is expressed. en_US
dc.description.librarian am2013 en_US
dc.description.librarian ay2013
dc.description.uri en_US
dc.identifier.citation Pentz, A, Moodley, T & Green, RJ 2013, 'The united airway - allergy and beyond', Current Allergy & Clinical Immunology, vol. 26, no. 2, pp. 71-74. en_US
dc.identifier.issn 1609-3607
dc.language.iso en en_US
dc.publisher Allergy Society of South Africa en_US
dc.rights Allergy Society of South Africa en_US
dc.subject United airway en_US
dc.subject Allergic rhinitis and asthma en_US
dc.subject.lcsh Immunological deficiency syndromes en
dc.title The united airway - allergy and beyond en_US
dc.type Article en_US

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