The united airway - allergy and beyond

dc.contributor.authorPentz, Adele
dc.contributor.authorMoodley, Teshni
dc.contributor.authorGreen, Robin J.
dc.date.accessioned2013-10-11T07:50:50Z
dc.date.available2013-10-11T07:50:50Z
dc.date.issued2013-06
dc.description.abstractThe concept of a 'united airway' became popular to link allergic rhinitis and asthma in many individuals who had symptoms of both upper and lower airway disease. Because of the common epithelium that runs all the way down the airway it is not surprising that in many individuals allergens trigger inflammation in both sites. However, the mere fact that some individuals have both symptoms of rhinitis and lower airway pathology does not mean the condition has an atopic basis. Since the airway has a limited number of ways of expressing symptoms, namely runny, sneezy, itchy and blocked nose, as well as cough or wheeze, these symptoms may also be produced in individuals who have quite a long list of other disease states. Although these are less common, healthcare workers will have to consider at some time that symptoms may be from primary ciliary dyskinesia, immune deficiency (primary or secondary), cystic fibrosis, Samter's triad or even recurrent viral airway infections. This article explores these conditions, suggesting their pathophysiology and symptom base. A clear message, to think of one of these conditions if symptoms do not have an allergy base and do not respond to first-line therapy, is expressed.en_US
dc.description.librarianam2013en_US
dc.description.librarianay2013
dc.description.urihttp://www.allergysa.org/journal.htmen_US
dc.identifier.citationPentz, A, Moodley, T & Green, RJ 2013, 'The united airway - allergy and beyond', Current Allergy & Clinical Immunology, vol. 26, no. 2, pp. 71-74.en_US
dc.identifier.issn1609-3607
dc.identifier.urihttp://hdl.handle.net/2263/32038
dc.language.isoenen_US
dc.publisherAllergy Society of South Africaen_US
dc.rightsAllergy Society of South Africaen_US
dc.subjectUnited airwayen_US
dc.subjectAllergic rhinitis and asthmaen_US
dc.subject.lcshImmunological deficiency syndromesen
dc.titleThe united airway - allergy and beyonden_US
dc.typeArticleen_US

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