Van der Westhuizen, Carl Johan; Van Greunen, D.G. (Divan); Cordier, Werner; Nell, Margo Judith; Steenkamp, Vanessa; Stander, Andre; Panayides, Jenny-Lee; Riley, Darren L.
(ARKAT, 2020-04)
β-Secretase (BACE1) is recognised as a target for the treatment of Alzheimer’s disease, and transition-state
isosteres such as hydroxyethylamines have shown promise when incorporated into BACE1 inhibitors. A
computational ...