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Browsing Pharmacology by Subject "Tetrachloro-1,4-benzoquinone (TCBQ)"

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Comparative toxicity of pentachlorophenol with its metabolites tetrachloro-1,2-hydroquinone and tetrachloro-1,4-benzoquinone in HepG2 cells

Schroeder, Ilka Elizma; Van Tonder, Jacob John; Steenkamp, Vanessa (Bentham Science, 2012)

The organochlorine compound, pentachlorophenol (PCP), is classified as a hazardous substance. Its metabolite, tetrachloro-1,2-hydroquinone (TCHQ), has been detected in occupationally-exposed subjects and can readily be ...
Cytotoxic activity of pentachlorophenol and its active metabolites in SH-SY5Y neuroblastoma cells

Fraser, Desiree Linda; Stander, Barend Andre; Steenkamp, Vanessa (Elsevier, 2019-08)

As knowledge regarding mechanisms of pentachlorophenol (PCP) toxicity in neuronal cell lines is limited, the aim of the study was to evaluate the effects of PCP and its active metabolites, tetrachloro-1,4-benzoquinone ...

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