Browsing Pharmacology by Subject "Reactive oxygen species"

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Determination of the in vitro antidiabetic potential of a polyherbal commercial tea

Paddy, Veronica (University of Pretoria, 2014)

Type 2 diabetes mellitus (T2DM) is an increasing global health concern, currently affecting an estimated 382 million individuals. There is no cure for T2DM and the search for new and improved treatments is ongoing. Presently, ...
Effects of polyphenolic-rich bark extracts of Burkea africana and Syzygium cordatum on oxidative stress

Cordier, Werner (University of Pretoria, 2013-01-07)

Free radicals have been implicated in the progression of various diseases, such as cancers and cardiomyopathies. When the body is overburdened with free radicals and endogenous antioxidants become depleted, oxidative stress ...
Pyrrolizidine alkaloids enhance alcohol-induced hepatocytotoxicity in vitro in normal human hepatocytes

Neuman, M.G.; Cohen, L.B.; Steenkamp, Vanessa (Verduci Publishers, 2017-03)

OBJECTIVE : Herbal remedies containing pyrrilidozine alkaloids (PA)s can induce liver damage, including hepato-sinusoidal obstruction syndrome (HSOS) or veno-occlusive liver disease (VOD). Some individuals misusing ...

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