Browsing Pharmacology by Title

Browsing Pharmacology by Title

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  • Tackling antimicrobial resistance across sub-Saharan Africa : current challenges and implications for the future 
    Godman, Brian; Egwuenu, Abiodun; Wesangula, Evelyn; Schellack, Natalie; Kalungia, Aubrey Chichonyi; Tiroyakgosi, Celda; Kgatlwane, Joyce; Mwita, Julius; Patrick, Okwen; Niba, Loveline Lum; Amu, Adefolarin A.; Oguntade, Racheal Tomilola; Alabi, Mobolaji Eniola; Ncube, Nondumiso B.Q.; Sefah, Israel Abebrese; Acolatse, Joseph; Incoom, Robert; Guantai, Anastasia Nkatha; Oluka, Margaret; Opanga, Sylvia; Chikowe, Ibrahim; Khuluza, Felix; Chiumia, Francis K.; Jana, Collins Edward; Kalemeera, Francis; Hango, Ester; Fadare, Joseph; Ogunleye, Olayinka O.; Ebruke, Bernard E.; Meyer, Johanna C.; Massele, Amos; Malande, Oliver Ombeva; Kibuule, Dan; Kapona, Otridah; Zaranyika, Trust; Bwakura-Dangarembizi, Mutsa; Kujinga, Tapiwanashe; Saleem, Zikria; Kurdi, Amanj; Shahwan, Moyad; Jairoun, Ammar Abdulrahman; Wale, Janney; Brink, Adrian (Taylor and Francis, 2022)
    INTRODUCTION : Antimicrobial resistance (AMR) is a concern as this increases morbidity, mortality, and costs, with sub-Saharan Africa having the highest rates globally. Concerns with rising AMR have resulted in international, ...
  • Targeting specific checkpoints in the management of SARS-CoV-2 induced cytokine storm 
    Abubakar, Abdullahi Rabiu; Ahmad, Rahnuma; Rowaiye, Adekunle Babajide; Rahman, Sayeeda; Iskandar, Katia; Dutta, Siddhartha; Oli, Angus Nnamdi; Dhingra, Sameer; Tor, Maryam Abba; Etando, Ayukafangha; Kumar, Santosh; Irfan, Mohammed; Gowere, Marshall; Chowdhury, Kona; Jahan, Dilshad; Schellack, Natalie; Haque, Mainul (MDPI, 2022-03-25)
    COVID-19-infected patients require an intact immune system to suppress viral replication and prevent complications. However, the complications of SARS-CoV-2 infection that led to death were linked to the overproduction ...
  • Teaching pharmacology online : not just another narration 
    Cordier, Werner; Lubbe, J.C. (Irene) (Health and Medical Publishing Group, 2021-09)
    The COVID-19 pandemic placed educators in unique circumstances, not only due to their discipline- and student-specific considerations, but also their personal and professional milieu. Given a series of sudden ...
  • The combined effects or arsenic cadmium and mercury on hepatocarcinoma and neuroblastoma cells in vitro 
    Yousaf, Muhammad (University of Pretoria, 2018)
    Among several heavy metallic elements, arsenic, cadmium and mercury are most toxic in the environment. These metals are acquired by humans through food and water, which result in severe health related issues. One of the ...
  • The effect of three Ghanaian plants on fibroblast migration, inflammation and bacterial growth in vitro 
    Yahaya, Ewura Seidu (University of Pretoria, 2018)
    Medical conditions which cause morbidity and mortality, such as chronic wounds and infection, lead to significant medical costs. Much of the world's population is dependent on alternative medicine, of which herbal medicine ...
  • The prevalence of eight single nucleotide variations in overweight and obese participants 
    Sansom, Bianca (University of Pretoria, 2018)
    Introduction Obesity is a growing epidemic not just nationally but worldwide and is responsible for a substantial economic burden in both developed and developing countries. Obesity is a major risk factor for type 2 ...
  • This too shall pass : coronaphobia and other fears 
    Outhoff, Kim (Medpharm Publications, 2020-06)
    “The heart's memory eliminates the bad and magnifies the good, and thanks to this artifice, we manage to endure the burden of the past.” Gabriel García Márquez, 1985, Love in the Time of Cholera.
  • To clot, or not to clot –antithrombotic therapy is the question 
    Osuch, Elzbieta; Marais, Andre (AOSIS Open Journals, 2019)
    Haemostasis and thrombosis rely on three components namely the vascular endothelial wall, blood platelets and the coagulation cascade. Non-physiologic excessive thrombosis occurs when haemostatic processes are dysfunctional, ...
  • Topical management of acne vulgaris using carbohydrate-derived fulvic acid (CHD-FA) 
    Scott, Arthur John (University of Pretoria, 2010-10-05)
    Objectives: In this pilot study, our intention was to ascertain what formulation of a carbohydrate-derived fulvic acid (CHD-FA) topical applicator was optimal for patients to use during a larger study where the efficacy ...
  • The toxicity and therapeutic index of a methotrexate polymeric compound, D-85 
    Visser, Suzaan (University of Pretoria, 2008-09-23)
    Methotrexate (MTX) has been used for many years in the treatment of patients with cancer as a cytotoxic agent and as an anti-inflammatory drug for the treatment of inflammatory diseases, such as rheumatoid arthritis (RA). ...
  • Toxicity profile of pyrrolizidine alkaloid-containing medicinal plants : Emphasis on Senecio species 
    Neuman, Manuela G.; Steenkamp, Vanessa (Global Science Books, 2009-12)
    Please read abstract in article.
  • Toxicity testing of two medicinal plants, Bridelia micrantha and Antidesma venosum 
    Steenkamp, Vanessa; Mokoele, T.L.; Jansen van Rensburg, Connie E. (Bentham Science, 2009)
    A. venosum and B. micrantha are widely used ethnomedically and B. micrantha has furthermore indicated the potential to be developed into a drug due to the various biological activities previously reported. However, the ...
  • The toxicity, pharmacokinetics, anti-inflammatory and anti-tumour properties of a methotrexate polymer 
    Sayed, Sharfuddin Sakil (University of Pretoria, 2010-05-12)
    A major effort to develop anticancer drugs through both empiric screening and rational design of new compounds has been under way for over 30 years (Katzung, 2004). In recent years, research and development in the field ...
  • Treatment of acute wounds and injuries : cuts, bites, bruises and sprains 
    Mlambo, Shamiso Shelter; Parkar, Hafiza; Naude, L.; Cromarty, Allan Duncan (Medpharm Publications, 2022)
    Acute wounds and injuries are a common daily occurrence, and their appropriate care is critical to healing. In South Africa, community pharmacists are often the first to encounter acute wounds and injuries such as cuts, ...
  • Treatment of the common cold with herbs used in Ayurveda and Jamu : monograph review and the science of ginger, liquorice, turmeric and peppermint 
    Wardani, Retno S.; Schellack, Natalie; Govender, Tamlyn; Dhulap, Abhay N.; Utami, Prapti; Malve, Vinod; Wong, Yong Chiat (Bioexcel Publishing, 2023-06)
    BACKGROUND : The common cold is typically managed with decongestants, antihistamines, antitussives and antipyretics. In addition to these established medications, herbal ingredients have been used over centuries to help ...
  • Trends in pharmacotherapy selection for the treatment of alcohol withdrawal in the Free State Province, South Africa 
    Van Zyl, P.M.; Gagiano, C.A.; Mollentze, W.F.; Snyman, J.S.; Joubert, G. (Psychological Society of South Africa, 2013-11)
    BACKGROUND. The selection of pharmacotherapy for the treatment of alcohol withdrawal remains a clinical challenge. Research continues into the underlying pathophysiology of dependence and withdrawal. A spectrum of clinical ...
  • Tricarbonyl(ŋ 6-flavone)chromium(0) 
    Van Tonder, Johannes H.; Bezuidenhoudt, Barend C.B.; Janse van Rensburg, J. Marthinus (International Union of Crystallography, 2009-11)
    In the title compound, [Cr(C15H10O2)(CO)3], the Cr(CO)3 unit exhibits a three-legged piano-stool conformation. The chromium metal centre is coordinated by the phenyl ring of the flavone ligand [Cr-(phenyl centroid) distance ...
  • Tricarbonyl(ŋ6-4′,7-dimethoxyiso-flavone) chromium(0) 
    Van Tonder, Johannes H.; Bezuidenhoudt, Barend C.B.; Janse van Rensburg, J. Marthinus (International Union of Crystallography, 2009)
    The metal atom of the Cr(CO)3 unit of the title compound, [Cr(C17H14O4)(CO)3], is coordinated to the methoxyphenyl ring of the isoflavone ligand; the Cr(CO)3 unit exhibits a three-legged piano-stool conformation. The ...
  • Undergraduate antibiotic stewardship training : are we leaving our future prescribers ‘flapping in the wind’? 
    Adriaan, Brink; Schoeman, Johan P.; Muntingh, George L. (Health and Medical Publishing Group, 2017-05)
    A multisite survey of South African (SA) medical students’ perceptions and knowledge of antibiotic resistance (ABR) and appropriate prescribing by Wasserman et al., published in this edition of the SAMJ, demonstrates ...
  • Underlying causes of chronic bladder dysfunction 
    Marais, Andre; Osuch, Elzbieta (Medpharm Publications, NISC (Pty) Ltd and Cogent, Taylor and Francis Group, 2018)
    General practitioners and family physicians frequently encounter patients suffering from voiding disorders. Various underlying causes such as spinal cord injury, cerebrovascular accidents, traumatic brain injury and several ...